Results 131 to 140 of about 117,362 (295)

Sustainable Microwave‐Enhanced Synthesis of 2‐Substituted Benzofurans From o‐Alkynylanisoles in Acidic Deep Eutectic Solvents

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A microwave‐enhanced sustainable and versatile approach to substituted benzofurans from 2‐alkynylanisoles enabled by an active Brønsted acidic deep eutectic solvent. The research on alternative media for organic transformations remains a highly demanding topic.
Alessandra Gritti   +9 more
wiley   +1 more source

Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley   +1 more source

Stereo‐EEG mapping of visual working memory with task‐related high‐gamma modulations

open access: yesEpilepsia, EarlyView.
Abstract Objective We describe a safe, informative, and easy‐to‐implement approach for presurgical mapping of visual working memory (VWM) with stereo‐electroencephalography (SEEG). Methods Twenty‐four patients with drug‐resistant epilepsy, 11–23 years of age, performed a single‐probe change detection VWM task, during SEEG monitoring.
Brian Ervin   +13 more
wiley   +1 more source

Deprotonative C(sp<sup>3</sup>)/C(sp<sup>2</sup>)-H (Multi)Silylation of (Hetero)Arenes Mediated by NaTMP. [PDF]

open access: yesAngew Chem Int Ed Engl
An operationally simple protocol using a strongly basic sodium amide in combination with sterically emcumbered silicon electrophiles enables the deprotonative C–H (multi)silylation of a myriad of (hetero)arenes. Mechanistic investigations highlight the pivotal role of steric and coordination effects in controlling the regioselectivity and efficiency of
Sánchez-Roa D   +6 more
europepmc   +2 more sources

Creativity and its link to epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Constructing better electrode–electrolyte interphases in sodium‐ion battery cathodes

open access: yesInfoMat, EarlyView.
Recent work on the engineering of electrode–electrolyte interphases (EEIs) in sodium‐ion batteries (SIBs) cathode materials has been summarized. The classifications and corresponding problems are presented, followed by electrolyte, auxiliary, and electrode engineering methods.
Junpeng Xie   +4 more
wiley   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Regiodivergent Metalation of Pyridines Using Mixed TMP-Titanate and TMP-Fe-Titanate Bases

open access: yes
Abstract Functionalization of pyridine rings via direct metalation remains challenging because of issues pertaining to functional group compatibility under mild conditions, regiodivergence and coupling reactions of 2-pyridyl organometallics. Here we report two novel, practical and readily available TMP-based metallic reagents: Ti-1⋅2(TMPMgCl ...
Xinfang Duan   +3 more
openaire   +1 more source

UGT1A1 Fragment Analysis: Genotyping the (TA)n Variable Repeat Polymorphism for Clinical Applications

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study developed a PCR‐based fragment analysis assay for UGT1A1 rs3064744 targeting TA5 (*36), TA6 (*1), TA7 (*28), and TA8 (*37). The assay was CLIA validated with data showing 100% concordance and a sensitivity of 0.5 ng/uL. The assay was then implemented in a patient cohort of n = 940 and the results compared with PharmacoScan.
Ryan N. Baugher   +6 more
wiley   +1 more source

How I Do It: A Stepwise Surgical Technique for Fisch Class B Glomus Tympanicum

open access: yesThe Laryngoscope, EarlyView.
We describe a stepwise retroauricular microsurgical workflow for bulky tympanic paragangliomas, combining circumferential canaloplasty with temporary removal and replacement of the tympanomeatal flap and malleus to optimize exposure and bleeding control.
Stéphane Gargula   +8 more
wiley   +1 more source

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