Results 111 to 120 of about 8,086 (190)
Comprehensive Analysis of Genomic Variations in Pancreatic Adenocarcinoma by Race
Cancer Medicine, Volume 14, Issue 21, November 2025.ABSTRACT Purpose
Racial disparities in pancreatic ductal adenocarcinoma (PDAC) incidence and outcomes persist even after adjusting for access to care and treatment received, suggesting a role for tumor‐specific molecular factors. This study aimed to compare the mutational landscape of PDAC tumor samples across racial groups using a large, diverse ...Mohamad El Moheb, Kaelyn C. Cummins, Chengli Shen, Elio R. Bitar, Susan J. Kim, Mackenzie M. Mayhew, Hongji Zhang, Russell G. Witt, Samantha M. Ruff, Allan Tsung +9 morewiley +1 more sourceThe molecular and cellular origin of human prostate cancer [PDF]
, 2016 Prostate cancer is the most commonly diagnosed male malignancy. Despite compelling epidemiology, there are no definitive aetiological clues linking development to frequency.Abate-Shen, Abrahamsson, Adler, Al-Hajj, Albini, Ammirante, An, An, Anderson, Anderson, Antonarakis, Ao, Armitage, Baca, Baker, Bapat, Barbieri, Barker, Barsky, Beck, Beltran, Ben-Neriah, Bergh, Bernstein, Berry, Bethel, Birkeland, Birnie, Blackwood, Bonnet, Borel, Bostwick, Bostwick, Boysen, Briganti, Bubendorf, Burkhardt, Caini, Cairns, Calabrese, Cancer Research UK, Carreira, Cesare, Chakkalakal, Chapman-Rothe, Chen, Cheshier, Choi, Chua, Clevers, Cloos, Cohen, Cohen, Collins, Collins, Conboy, Cooper, Culig, Culig, Cunha, Cunha, Dan Robinson, Das, Dawson, De Marzo, De Marzo, Dehm, Deng, Dermer, Ding, Don-Doncow, Donaldson, Dong, Ebelt, Eggener, Eminaga, Epstein, Eramo, Essers, Fang, Fassi Fehri, Fearon, Feinberg, Feng, Fialkow, Figueiredo, Foudi, Frame, Frame, Frame, Franco, Franks, Gan, Gannon, Gao, Gendrel, Gerlinger, Germann, Ghajar, Gibbs, Gimelbrant, Gleason, Gleave, Goardon, Goldstein, Gong, Goodwin, Gotay, Grasso, Grasso, Greaves, Grisanzio, Gundem, Guo, Gupta, Gurel, Guryanova, Gutierrez-Arcelus, Haapala, Haas, Haffner, Haffner, Haffner, Haffner, Hahn, Hall, Hall, Han, Hanahan, Hansel, He, Heaphy, Hecht, Heer, Herawi, Hermann, Hernandez, Heydt, Hjelmeland, Hong, Hong, Hovelson, Hrbacek, Hu, Huels, Huggins, Hurt, Hurt, Hägglöf, IACR, Iliopoulos, Iliou, Inaguma, Isaacs, Jafari, Jiao, Jin, John R. Packer, Johnston, Jones, Jones, Joseph, Karanika, Karantanos, Karthaus, Ke, Ke, Keller, Kelly, Kiel, Kim, Kooistra, Korpal, Kouzarides, Kovtun, Kreso, Krieger, Krieger, Kroon, Kulac, Kunderfranco, Lang, Lang, Lanie, Lapointe, Lark, Lavery, Lee, Lee, Leong, Leongamornlert, Li, Li, Li, Li, Lilja, Lin, Lin, Ling, Liu, Lo, Loeb, Luedeke, Lukacs, Ma, Mahmud, Maini, Maitland, Maitland, Maitland, Maitland, Mani, Marinov, Martin, Matsui, Meeker, Mehrotra, Menon, Merok, Metsalu, Metzger, Meyer, Michaud, Miyamoto, Mohan, Mounir, Munger, Nag, Nag, Nakai, Nakashima, Navarro, Nelson, Network, Nonn, Nonomura, Norman J. Maitland, Norrish, Nowell, O'Callaghan, O'Sullivan, Ohm, Olumi, Osman, Ousset, Park, Pascale, Patel, Patel, Patra, Patrawala, Patrawala, Pellacani, Penney, Perner, Perner, Perry, Peto, Pierce, Platz, Polson, Potten, Potter, Prince, Pritchard, Putzi, Qin, Rajan, Rando, Rane, Rane, Raval, Reik, Ricci-Vitiani, Ricci-Vitiani, Rich, Richardson, Riley, Risbridger, Robinson, Rodriguez, Rosa Mendoza, Ross-Adams, Roth, Ruska, Rutella, Sack, Sakr, Schiewer, Schober, Schroeder, Sfanos, Sfanos, Sfanos, Sfanos, Sharma, Sharma, Shen, Shibata, Shinohara, Shiozawa, Singh, Singh, Slaughter, Smith, Sneddon, Sommerfeld, Song, Song, Steinhauser, Stewart, Strand, Strasner, Stratton, Strickler, Sugimura, Suzuki, Tan, Tan, Tang, Taplin, Taylor, Tepper, Thompson, Ting, Ting, Toh, Tollervey, Tomasetti, Tomasetti, Tomasetti, Tomlins, Tomlins, Tomlinson, Tomlinson, Trock, True, Trumpp, Tuxhorn, Twillie, Urquidi, Ushijima, Valastyan, Van, Van Asperen, Vincent, Vindrieux, Visakorpi, Visvader, Vogelstein, Vral, Wang, Wang, Wang, Wang, Wang, Wang, Watt, Weinberger, Whitaker, Wild, Williams, Wilson, Woo, Wymenga, Xiang, Xiang, Xu, Yachida, Yamamoto, Yatabe, Yoshimoto, Yu, Zambrano, Zhang, Zhang, Zhang +376 morecore +1 more sourceEmerging aspects of microRNA interaction with TMPRSS2-ERG and endocrine therapy
Molecular and Cellular Endocrinology, 2018 Prostate cancer (PCa) is the most common malignancy detected in males and the second most common cause of cancer death in western countries. The development of the prostate gland, is finely regulated by androgens which modulate also its growth and function.Zoni, Eugenio, Karkampouna, Sofia, Thalmann, George N., Kruithof-de Julio, Marianna, Spahn, Martin +4 moreopenaire +3 more sourcesImpact of the SPOP Mutant Subtype on the Interpretation of Clinical Parameters in Prostate Cancer. [PDF]
, 2018 Purpose: Molecular characterization of prostate cancer, including The Cancer Genome Atlas, has revealed distinct subtypes with underlying genomic alterations.Alshalalfa, Mohammed, Barbieri, Christopher E., Davicioni, Elai, Den, Robert B., Erho, Nicholas, Jenkins, Robert B., Karnes, R. Jeffrey, Klein, Eric A., Liu, Deli, Ross, Ashley E., Rubin, Mark A., Sboner, Andrea, Schaeffer, Edward M., Shoag, Jonathan, Spratt, Daniel E., Takhar, Mandeep, Tomlins, Scott A., Trock, Bruce +17 morecore +1 more sourceEpigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy. [PDF]
, 2017 Androgen receptor (AR) signaling remains the major oncogenic pathway in prostate cancer (PCa). Androgen-deprivation therapy (ADT) is the principle treatment for locally advanced and metastatic disease.Cucchiara, Vito, Evans, Christopher P, Gao, Allen C, Mirone, Vincenzo, Rosenfeld, Michael G, Yang, Joy C +5 morecore +2 more sourcesCCL11 (eotaxin‐1): A new diagnostic serum marker for prostate cancer [PDF]
, 2012 BACKGROUND The recent recommendation of the U.S. Preventive Services Task Force against PSA‐based screening for prostate cancer was based, in part, on the lack of demonstrated diagnostic utility of serum PSA values in the low, but detectable range to ...Agarwal, Manisha, He, Chang, Macoska, Jill A., Siddiqui, Javed, Wei, John T. +4 morecore +1 more sourceLrf suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion [PDF]
, 2014 Lrf has been previously described as a powerful proto-oncogene. Here we surprisingly demonstrate that Lrf plays a critical oncosuppressive role in the prostate.Ala, Ugo, Carver, Brett, Chen, Zhenbang, Cordon-Cardo, Carlos, Egia, Ainara, Gerald, William L., Gonzalez-Billalabeitia, Enrique, Kuo, Winston Patrick, Liu, Xue-Song, Lunardi, Andrea, Nardella, Caterina, Pandolfi, Pier Paolo, Shaffer, David R., Signoretti, Sabina, Taulli, Riccardo, Tay, Yvonne, Wang, Guocan, Webster, Kaitlyn A., Zhang, Jiangwen +18 morecore +1 more source