Results 51 to 60 of about 114,749 (312)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Magnetic characterisation of Tm/Y and Tm/Lu superlattices

open access: yesJournal of Magnetism and Magnetic Materials, 1999
Single-crystal Tm/Y and Tm/Lu superlattices have been grown using molecular beam epitaxy and their chemical structures have been determined using X-ray diffraction. Magnetisation measurements have revealed a more complicated phase diagram than that of pure Tm.
Wilkins, C   +6 more
openaire   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Cognitive Control, Not Time, Determines the Status of Items in Working Memory

open access: yesJournal of Cognition, 2020
Despite the fact that multiple items can be held in working memory (WM), it is often the case that only one of these is relevant for guiding in-the-moment behavior. Therefore, understanding how priority is established and controlled in WM is an important
Jacqueline M. Fulvio, Bradley R. Postle
doaj   +1 more source

Battlespace Next(TM).

open access: yesInt. J. Serious Games, 2020
Changes in the geopolitical landscape and increasing technological complexity have prompted the U.S. Military to coin the terms Multi-Domain Operations (MDO) and Joint All-Domain Command and Control (JADC2) as over-arching strategy to frame the complexity of warfare across both traditional and emerging warfighting domains.
Nathaniel Flack   +3 more
openaire   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

On the Mechanisms of Transcranial Magnetic Stimulation (TMS): How Brain State and Baseline Performance Level Determine Behavioral Effects of TMS [PDF]

open access: yes, 2018
The behavioral effects of Transcranial Magnetic Stimulation (TMS) can change qualitatively when stimulation is preceded by initial state manipulations such as priming or adaptation.
Marelli, M.   +7 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Teleworking, Team Work and Transactive Memory during the COVID-19 Outbreak

open access: yesManagement Dynamics in the Knowledge Economy, 2021
The paper discusses the work from home (WFH) phenomenon during the Covid-19 pandemic and aspects related to teamwork performance for the case of companies operating in Romania in knowledge-intensive business services (KIBS).
Andrei Ana-Maria
doaj   +1 more source

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