Results 261 to 270 of about 683,828 (283)

Distribution of sialosyl Tn and Tn antigens within normal and malignant colorectal epithelium

The Journal of Pathology, 1995
Abstract Expression of the core blood group structures sialosyl Tn (STn) and Tn is regarded as a colorectal cancer‐specific change reflecting truncated synthesis of the oligosaccharide component of goblet cell mucin. The distribution of STn and Tn in normal and malignant epithelium has been studied in detail by a combination of mucin‐,
J R, Jass, L J, Allison, S G, Edgar
openaire   +2 more sources

TN, A General Carcinoma-Associated Antigen

1985
Abstract Tn antigen, the immediate precursor in the biosynthesis of T (Thomsen-Friedenreich) antigen does not occur in immunoreactive form in healthy tissues. However, we found it in about 90% of all primary carcinomas (CAs) and their metastases, as well as in the two T lymphomas studied. Thus, Tn is a CA-associated antigen.
G.F. SPRINGER, H. TEGTMEYER, P.R. DESAI, E.F. SCANLON, C.R. TAYLOR   +4 more
openaire   +1 more source

Critical Care Management of Chimeric Antigen Receptor T-Cell Therapy Recipients

Ca-A Cancer Journal for Clinicians, 2022
Sandrine Valadè, Peter Schellongowski, Alexander Shimabukuro-Vornhagen   +2 more
exaly  

Chimeric Antigen Receptor T-Cell Therapy in Multiple Myeloma: A Comprehensive Review of Current Data and Implications for Clinical Practice

Ca-A Cancer Journal for Clinicians, 2023
Sagar Lonial, Rujul Parikh
exaly  

Expression of Tn and sialyl Tn antigens in synovial tissues in rheumatoid arthritis.

Clinical and experimental rheumatology, 2010
The carbohydrate chains represented by mucins (MUCs) are expressed by a variety of normal and malignant secretory epithelial cells and induce a variety of immunoreactions. Tn and sialyl Tn antigens are tumour-associated carbohydrate antigens which are borne on the core proteins of mucins.
H, Ishino, Y, Kawahito, M, Hamaguchi, N, Takeuchi, D, Tokunaga, T, Hojo, M, Wada, A, Yamamoto, M, Kadoya, Y, Tsubouchi, M, Kohno, H, Nakada   +11 more
openaire   +1 more source

Expression of Tn, sialosyl-Tn, and T antigens in human colon cancer.

Cancer research, 1989
Mucin glycoproteins are major secretory products of the colon and contain O-linked oligosaccharides synthesized on a polypeptide backbone. The initial step in the synthesis of O-linked oligosaccharides is the addition of N-acetylgalactosamine to serine or threonine residues forming the Tn antigen. This substance can then receive additional carbohydrate
S H, Itzkowitz, M, Yuan, C K, Montgomery, T, Kjeldsen, H K, Takahashi, W L, Bigbee, Y S, Kim   +6 more
openaire   +1 more source

A Guide to Antigen Processing and Presentation

Nature Reviews Immunology, 2022
Hidde Ploegh, Thibault J Harmand, Novalia Pishesha   +2 more
exaly  

83D4; antigen: Tn

Hybridoma, 1997
openaire   +1 more source

A Review of Cancer Immunotherapy Toxicity

Ca-A Cancer Journal for Clinicians, 2020
Lucy Boyce Kennedy
exaly  

Prostate-Specific Antigen: Current Status

Ca-A Cancer Journal for Clinicians, 1999
Michael K Brawer, M K Brawer
exaly