Impaired hematopoiesis affects apheresis and CAR T‐cell product composition and treatment response
Abstract Background Chimeric antigen receptor (CAR) T‐cell therapy has transformed the treatment of hematologic malignancies, but its success depends on obtaining sufficient CD3+ T‐cell yields during leukapheresis. This can be difficult in heavily pretreated patients, who often show leukopenia and reduced T‐cell fitness.
Hanna Kuhn +14 more
wiley +1 more source
DC-CD4 bispecific tolerogenic nanovesicles induce antigen-specific regulatory T cells and ameliorate collagen-induced arthritis in mice. [PDF]
Zhao L +9 more
europepmc +1 more source
α-Galactosylceramide-expanded virtual memory CD8<sup>+</sup> T cells confer protection against a broad range of pathogens. [PDF]
Xie JX +6 more
europepmc +1 more source
Process Safety Assessment of the Iron-Catalyzed 1,2-<i>cis</i>-Selective Glycal Aminoglycosylation. [PDF]
Zhang D +5 more
europepmc +1 more source
Deletion of Core 1 β3GalT-specific molecular chaperone (Cosmc) in murine intestinal epithelia leads to major alterations in glycocalyx and tumorigenesis. [PDF]
Ju T +11 more
europepmc +1 more source
Retreatment with talquetamab and pomalidomide in triple‐class–BCMA–GPRC5D refractory myeloma
British Journal of Haematology, Volume 209, Issue 1, Page 320-323, July 2026.
Kian J. Rahbari +4 more
wiley +1 more source
Soluble IL-2 receptor and memory Treg profiles differentiate early rheumatoid arthritis from undifferentiated arthritis at initial presentation. [PDF]
Zi X, Shi Y, Zhao Y, Gao C, Wang C.
europepmc +1 more source
GALNT7-induced O-glycosylation of NUP50 activates fatty acid β-oxidation to promote lung adenocarcinoma metastasis. [PDF]
Sheng M, Yu B, Wang Q, Xiao Y, Wu X.
europepmc +1 more source

