Results 211 to 220 of about 551,022 (291)
ABSTRACT Background Clinical T 2‐weighted (T2W) MRI of prostate cancer (PCa) usually implements a 2D fast‐spin‐echo (FSE) sequence, but understanding the echo‐time‐dependent contrast behavior is not straightforward due to the complicated FSE signal evolution.
Dahan Kim +10 more
wiley +1 more source
Systematic Review of AI‐Driven Applications for Screening Nasopharyngeal Carcinoma Using MRI
ABSTRACT Background Nasopharyngeal carcinoma (NPC) can be detected early on MRI, but adoption for screening is limited by a shortage of experienced specialists. MRI artificial intelligence (AI) algorithms for diagnosing NPC in the literature may address this, but most studies focus on routine clinical care, and their applicability in screening requires
Lun M. Wong +7 more
wiley +1 more source
Control of naive T cell reactivity and peripheral tolerance by ascorbate and TET activity. [PDF]
Hao X +19 more
europepmc +1 more source
This prospective study evaluated envafolimab plus chemotherapy in 29 SCLC patients with liver metastases, integrating multi‐omics analyses (WES, RNA‐seq, DNA methylation, ctDNA, and cfDNA methylation). The research framework encompassed granulocyte turnover dynamics, prognostic risk modeling, molecular mechanism exploration across risk strata, and ...
Ning Tang +11 more
wiley +1 more source
Oxysterols in Cancer: From Biosynthesis and Pathophysiology to Targeted Therapeutics
Mechanisms by which oxysterol targeting may enhance immunotherapy efficacy. This figure illustrates potential metabolic interventions that may improve antitumor immunity by modulating oxysterol related pathways. CH25H modulation may reduce 25‐HC accumulation, promote the conversion of cold tumors into hot tumors, and increase T cell infiltration and PD‐
Haili Shang, Yongsheng Li
wiley +1 more source
A 70‐year‐old man with interstitial lung disease developed a fever and facial rash, with new bilateral ground‐glass opacities on high‐resolution computed tomography. Parvovirus B19 infection was confirmed, suggesting viral infection as a trigger of acute exacerbation through direct and immune‐mediated mechanisms.
Tomoki Kishaba +11 more
wiley +1 more source
Intermediate clinical endpoints as surrogates for overall survival after salvage prostatectomy
Objectives To evaluate biochemical recurrence‐free survival (BRFS) and metastasis‐free survival (MFS) as potential intermediate clinical endpoints (ICEs) for overall survival (OS) in patients undergoing salvage radical prostatectomy (sRP). Patients and Methods Evaluable patients were selected from a retrospective dataset, resulting in a cohort of 879 ...
Navid Roessler +22 more
wiley +1 more source
Single-cell RNA sequencing reveals immune microenvironment heterogeneity in BRCA1-mutated and sporadic triple-negative breast cancer. [PDF]
Sun Q, Zhong Y, Sun C.
europepmc +1 more source

