Results 151 to 160 of about 621,266 (288)

Piper nigrum Has an Antitumor Effect Through Regulation of the Phosphatidylinositol 3‐Kinase Signaling Pathway in a Murine Model of Acute Myeloid Leukemia

Phytotherapy Research, EarlyView.
Overview of the antileukemic effects of Piper nigrum extract in AML. P. nigrum reduced leukemic cell proliferation and glycolytic metabolism through modulation of the PI3K/AKT/mTOR pathway. In vivo, treatment reduced leukemic burden, improved hematological parameters, prolonged survival, and modulated antitumor immune responses.
Natalia Murillo, Paola Lasso, Claudia Urueña, Susana Fiorentino   +3 more
wiley   +1 more source

Electrocatalytically Amplified Immunosensing Enabled by Titanium Oxynitride‐Supported Ru Nanodots on Graphene Oxide Hybrid Architecture

Small, EarlyView.
A synergistic effect among the electrocatalytic Ru/TiON‐GO nanocomposite, biorecognition elements, and the [Fe(CN)6]3−/4− redox probe for highly sensitive and selective impedimetric detection of PSA protein in human serum was demonstrated. The immunosensor exhibited a limit of detection of only 0.06 ng mL−1 PSA protein, underscoring the importance and ...
Mitja Koderman, Milutin Smiljanić, Filip Cernatič, Marjan Bele, Francisco Ruiz‐Zepeda, Nejc Hodnik, Mitja Kolar, Samo B. Hočevar, Nikola Tasić   +8 more
wiley   +1 more source

Sialyl Tn Antigen [PDF]

, 2020
openaire   +1 more source

Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow

VIEW, EarlyView.
Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow. Abstract Metagenomic next‐generation sequencing (mNGS) enables unbiased identification of pathogens directly from clinical specimens. Despite its growing application in
Wen Shu, Qiaomei Guo, Han Yang, Huiqin Jiang, Chunyan He, Xueqing Wang, Yuting Fang, Yue Yin, Liwen Zhong, Zhijing Zhao, Jiatao Lou, Lin Wang   +11 more
wiley   +1 more source

The Synthesis of Natural Tn Antigen Carbohydrate Vaccines

The Synthesis of Natural Tn Antigen Carbohydrate Vaccines Aiyireti (Dina) Dilinaer, Michael R. Reynolds, S. Iraj Sadraei, John F. Trant The immune system plays an important role in defending the human body against diseases and invasion of pathogens. When
Reynolds, Michael R., Dilinaer, Aiyireti, Trant, John F., Sadraei, Seyed Iraj   +3 more
core   +1 more source

Design, synthesis, and initial immunological evaluation of glycoconjugates based on saponin adjuvants and the Tn antigen.

Chem Commun (Camb), 2021
Fuentes R, Aguinagalde L, Sacristán N, Fernández-Tejada A.   +3 more
europepmc   +1 more source

Transposons as Tools for Future Genome Engineering in Yeasts and Filamentous Fungi

Yeast, EarlyView.
Applications of transposon‐based tools for genome engineering in fungi include transposon‐mediated mutagenesis and targeted genomic integration. ABSTRACT Transposons are fundamental genetic elements that have profoundly shaped the architecture of eukaryotic genomes.
Bingyin Peng, Masahiro Tominaga, Chengqiang Wang, Robert E. Speight, Jun Ishii   +4 more
wiley   +1 more source

Targeting the cancer glycocalyx in salivary duct carcinoma: tumor‐associated mucin 1 (Tn‐MUC1) as a novel cell surface marker

The Journal of Pathology: Clinical Research
Despite the use of targeted drugs for human epidermal growth factor receptor type 2 (HER2)‐positive salivary duct carcinoma (SDC) treatment, the overall prognosis for SDC remains poor.
Masashi Kuroki, Ryo Kawaura, Hiroyuki Tomita, Hirofumi Shibata, Toshimitsu Ohashi, Tomohiko Ishikawa, Hideshi Okada, Akira Hara, Takenori Ogawa   +8 more
doaj   +1 more source

Tn Antigen Antibody [PDF]

, 2020
openaire   +1 more source

Microarrayed Allergen Molecules Distinguish IgE Sensitisation to Blomia tropicalis and Dermatophagoides pteronyssinus

Allergy, EarlyView.
This study established a microarray containing a representative panel of purified Blo t and Der p allergens for the identification of patients sensitised to Blo t and/or Der p. Results indicate that the microarray based on Blo t and Der p allergens is a useful tool for the identification of Blo t‐ and/or Der p‐sensitised patients. The microarray may be
Nishelle Dsouza, Siratcha Phanthong, Huey‐Jy Huang, Milena Weber, Eszter Sarzsinszky, Petra Zieglmayer, Gabrielle Pauli, Margarete Focke‐Tejkl, Mikhail Tulaev, Nikolina Todorovic, Walter Keller, Thomas Schlederer, Luis Caraballo, Anchalee Tungtrongchitr, Rudolf Valenta, Pongsakorn Tantilipikorn, Susanne Vrtala   +16 more
wiley   +1 more source