Results 91 to 100 of about 80,546 (217)

Diagnostic Impact of Two‐Dimensional Shear Wave Elastography for Liver Fibrosis: A Multicenter Retrospective Study

Hepatology Research, EarlyView.
Two‐dimensional shear wave elastography demonstrated strong correlation with magnetic resonance elastography and high diagnostic accuracy for liver fibrosis across stages in 744 patients with chronic liver disease, supporting its role as a reliable non‐invasive tool for fibrosis assessment.
Takashi Nishimura, Toshifumi Tada, Yasuaki Suzuki, Kento Imajo, Katsutoshi Sugimoto, Sadanobu Ogawa, Hidenori Toyoda, Tamami Abe, Hidekatsu Kuroda, Masashi Hirooka, Asako Nogami, Satoshi Oeda, Hirokazu Takahashi, Tomoyuki Akita, Reiichiro Kondo, Takuma Nakatsuka, Ryosuke Tateishi, Yoichi Hiasa, Yuichiro Eguchi, Atsushi Nakajima, Hirohisa Yano, Shigehiro Kokubu, Junko Tanaka, Fuminori Moriyasu, Masayoshi Kage, Takashi Kumada, Hiroko Iijima   +26 more
wiley   +1 more source

A Novel Diagnostic Approach for Hepatocellular Carcinoma Using Glycosylated Ferritin

Hepatology Research, EarlyView.
The percentage of glycosylated ferritin relative to total ferritin (%GF) is a novel biomarker for hepatocellular carcinoma (HCC), showing diagnostic performance comparable to that of AFP and DCP. We developed the GFAD index by integrating age, sex, %GF, AFP, and DCP, achieving improved diagnostic accuracy with high sensitivity and specificity. ABSTRACT
Akiyo Ishiguro, Yutaka Suehiro, Issei Saeki, Maho Egusa, Norikazu Tanabe, Toshihiko Matsumoto, Tsuyoshi Ishikawa, Yuki Kunimune, Toshihiko Kobayashi, Mitsuaki Nishioka, Taro Takami, Takahiro Yamasaki   +11 more
wiley   +1 more source

Studies on a Sulfoxide-Bridged Tn Antigen Mimetic: Interaction with Macrophage Galactose Lectin and Inhibition of Sialyltransferase ST6GALNAC1. [PDF]

ACS Omega
Sodini A, Casali E, Travecedo MA, Marcelo F, Chiodo F, Rambaldi F, van Vliet SJ, Dall'Olio F, Nativi C.   +8 more
europepmc   +1 more source

TROP2 immunoreactivity in pulmonary large cell neuroendocrine carcinoma

Histopathology, EarlyView.
Frequently positive TROP2 IHC suggests that TROP2 antibody‐drug conjugates may be potential treatments for LCNEC. Introduction TROP2 antibody‐drug conjugates have shown promising anti‐tumour activity, but neither the activity of these agents nor TROP2 expression has been well studied in pulmonary large cell neuroendocrine carcinoma (LCNEC), a rare and ...
Michael Minkley, Kashif Ravasia, Thi Nghiem, Dongxia Gao, Jamie Feng, Andrew Churg, Julia R Naso   +6 more
wiley   +1 more source

Overexpression of Tn antigen induces chronic pancreatitis in mice. [PDF]

Sci Rep
Mercanoglu B, Schraps N, Giannou AD, Neuburg E, Kempski J, Wagener C, Melling N, Bockhorn M, Hackert T, Wolters-Eisfeld G.   +9 more
europepmc   +1 more source

Mass Spectrometric Mapping of Glycoproteins Modified by Tn-Antigen Using Solid-Phase Capture and Enzymatic Release. [PDF]

Anal Chem, 2020
Yang W, Ao M, Song A, Xu Y, Sokoll L, Zhang H.   +5 more
europepmc   +1 more source

Serotypic and Genomic Diversity of Vibrio anguillarum in Rainbow Trout Farms in Turkey: Implications for Vibriosis Control and Vaccine Candidate Selection

Journal of Fish Diseases, EarlyView.
ABSTRACT Outbreaks of vibriosis caused by Vibrio anguillarum are a persistent constraint on rainbow trout (Oncorhynchus mykiss) aquaculture. However, information on the population structure of field strains in Turkey has been lacking. Here, we report the first systematic serotypic, proteomic, and genomic characterization of 23 V.
Soner Altun, Muhammed Duman, Jesús L. Romalde, Nihed Ajmi, Gorkem Tasci, Cuneyt Ozakin, Nazmiye Ulku Tuzemen, Bekir Akça, Sebahattin Ergün, Sevdan Yılmaz, Izzet Burcin Saticioglu   +10 more
wiley   +1 more source

Targeting Tn Antigen Suppresses Aberrant O-Glycosylation-Elicited Metastasis in Breast Cancer. [PDF]

J Cell Mol Med
Du T, Dong X, Tan J, Chen X, Liu J, Wen T, Ru X.   +6 more
europepmc   +1 more source

Elucidating the Staphylococcus aureus TSST‐1 Regulatory Network as a Response to Vaginal pH

Molecular Microbiology, EarlyView.
Toxic shock syndrome toxin‐1 (TSST‐1) is a potent Staphylococcus aureus superantigen responsible for menstrual toxic shock syndrome (mTSS). Regulation of TSST‐1 is controlled by multiple systems including the stand‐alone transcriptional regulators CcpA and SarA and two‐component systems including the redox sensor SrrAB, the membrane stress sensor SaeRS,
Carla S. Maduta, Nicholas R. Walton, Emily P. Barbosa, Erica N. DeJong, Karine Dufresne, John K. McCormick   +5 more
wiley   +1 more source

Stereoselective Multigram-Scale Tn Antigen Synthesis via the Iron-Catalyzed Glycal 1,2-<i>cis</i>-Aminoglycosylation. [PDF]

Org Lett
Yin L, Zhang D, Jiang Z, Xu H.
europepmc   +1 more source