In patients with lenalidomide‐refractory multiple myeloma from the BOSTON trial subgroup analysis,1 selinexor (SEL) dose reduction versus full dosing substantially improved efficacy outcomes, including higher overall response rate (74.3% vs. 55.6%), deeper responses (≥ very good partial response: 48.6% vs.
Muhamed Baljevic
wiley +1 more source
Studies on a Sulfoxide-Bridged Tn Antigen Mimetic: Interaction with Macrophage Galactose Lectin and Inhibition of Sialyltransferase ST6GALNAC1. [PDF]
Sodini A +8 more
europepmc +1 more source
AI‐based anatomical recognition for bladder neck dissection in robot‐assisted radical prostatectomy
Objective To develop an artificial intelligence (AI) system for anatomical recognition that can automatically identify key anatomical structures during bladder neck dissection in robot‐assisted radical prostatectomy (RARP), a critical yet technically demanding step.
Shinnosuke Fujiwara +12 more
wiley +1 more source
Mass Spectrometric Mapping of Glycoproteins Modified by Tn-Antigen Using Solid-Phase Capture and Enzymatic Release. [PDF]
Yang W +5 more
europepmc +1 more source
Long‐term oncological outcomes from a prospective cohort of patients with localised prostate cancer
Objectives To report long‐term oncological outcomes for men with clinically localised prostate cancer (PCa) treated with contemporary modalities in a population‐based United States cohort. Patients and Methods The Comparative Effectiveness Analysis of Surgery and Radiation (CEASAR) study prospectively enrolled men with clinically localised PCa from ...
Avi S. Baskin +17 more
wiley +1 more source
Targeting Tn Antigen Suppresses Aberrant O-Glycosylation-Elicited Metastasis in Breast Cancer. [PDF]
Du T +6 more
europepmc +1 more source
Polymeric α‐Hairpinin Allergens Induce a Functional Response via a Single Antibody
Allergy, EarlyView.
Gage O. Leighton +16 more
wiley +1 more source
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen +8 more
wiley +1 more source
Stereoselective Multigram-Scale Tn Antigen Synthesis via the Iron-Catalyzed Glycal 1,2-<i>cis</i>-Aminoglycosylation. [PDF]
Yin L, Zhang D, Jiang Z, Xu H.
europepmc +1 more source
SYNTHETIC VACCINES .1. SYNTHESIS OF MULTIVALENT TN ANTIGEN CLUSTER-LYSYLLYSINE CONJUGATES
SYNTHETIC VACCINES .1.
T TOYOKUNI (21031199) +2 more
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