Results 121 to 130 of about 253,142 (331)

INVESTIGATION OF CYTOKINE PROFILE IN PATIENTS WITH REACTIVE ARTHRITIS

Медицинская иммунология, 2014
. Pathogenesis of reactive arthritis (ReA) is not clear yet. Several trials suggest that increased production of proinflammatory cytokines is responsible for development of arthritis in ReA, while other studies report that Th1 cytokine response in ReA is
T. V. Gaponova, A. M. Lila, T. G. Shemerovskaya, G. A. Zakharova, T. N. Maslyaeva   +4 more
doaj   +1 more source

The effect of equine hyperimmune sera on TNF alpha activity in a L929 cell bioassay [PDF]

, 2006
In this pilot study we examined the effect of sera from a proprietary hyperimmune plasma product (Equiplas) on the activity of TNF: in an in vitro L929 cell bioassay. In brief, we report observations from 2 accessions of sera.
Johnson, M., Kotiw, M., Raghaven, C., Shiels, I. A., Wilson, R. P.   +4 more
core  

Real‐Time Evolutionary Landscape of the Bronchial Epithelium and Corresponding Dynamic Immune Cell Alterations in Lung Squamous Cell Carcinogenesis

Advanced Science, EarlyView.
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo, Yuting Luo, Sicheng Chen, Tiantian Yang, Bixia Liu, Xiting Liao, Xiaoke Zheng, Tian Tian, Jinxu Liu, Qinru Zhan, Xiaohua Situ, Zhongpeng Xie, Yanxia Wang, Zhe‐Sheng Chen, Honglei Chen, Zheng Yang, Zunfu Ke   +16 more
wiley   +1 more source

Plasma levels of IL-6, IL-10, IL-18, TNFα under the conditions of tobacco intoxication and after treatment with aminophthalhydrazide

Медицинская иммунология
In response to damaging factors, a cascade of cytokines is released, triggering the processes of inflammation and fibrogenesis. The purpose of our study was to evaluate the levels of cytokines (IL-6, IL-10, IL-18, TNFα) in blood plasma under conditions ...
O. V. Alpidovskaya
doaj   +1 more source

ASSOCIATION OF LETHAL OUTCOMES IN SURGICAL SEPSIS WITH ALLELIC VARIANTS OF TNF Α AND HEAT SHOCK PROTEIN (HSP70-2) GENES

Медицинская иммунология, 2014
. Taking into account close localization of genes encoding HSP70-2 and TNFα and mutual influence of their products upon development of septic process, we investigated allelic polymorphism in the coding region of HSP70-2 gene at position 1267, and a ...
A. V. Shevchenko, O. V. Golovanova, V. I. Konenkov, E. I. Streltsova   +3 more
doaj   +1 more source

BAG2 Inhibits Cervical Cancer Progression by Modulating Type I Interferon Signaling through Stabilizing STING

Advanced Science, EarlyView.
Based on IP‐MS analysis, BAG2 is confirmed to be essential for ubiquitination and protein homeostasis regulation of STING in cervical cancer. BAG2 inhibits the ubiquitination and degradation of STING by forming a complex with STUB1, thereby activating the type I IFN signaling pathway and inhibiting the development of cervical cancer.
Shijie Yao, Siming Chen, Anjin Wang, Ziyan Liang, Xuelian Liu, Yang Gao, Hongbing Cai   +6 more
wiley   +1 more source

Pro-inflammatory activation of monocytes in patients with immunoinflammatory rheumatic diseases

Медицинская иммунология
The development of subclinical atherosclerosis in patients with rheumatoid arthritis (RA) is associated with chronic inflammation, one of the key mechanisms of which may be abnormal activation of macrophages.Objective: To assess the characteristics of ...
E. V. Gerasimova, I. G. Kirillova, M. V. Shalygina, T. V. Popkova   +3 more
doaj   +1 more source

EFFECTS OF BACTERIAL LIGANDS OF PATTERN-RECOGNIZING RECEPTORS (PRR) ON MONOCYTE-LIKE THP-1 CELLS UPON THEIR TRANSENDOTHELIAL MIGRATION

Медицинская иммунология, 2014
. The aim of study was to compare the influence of lipopolysaccharide (LPS) component from Gram-negative bacteria (E. coli 055:B5), and a lysate of Gram-positive bacterium (Streptococcus pyogenes, type M1, strain 40/58) upon transendothelial migration ...
E. P. Starikova, D. I. Sokolov, L. A. Burova, S. A. Sel’kov, I. S. Freidlin   +4 more
doaj   +1 more source

DELAYED PRODUCTION OF INTERFERON-GAMMA (IFNγ) AND TUMOR NECROSIS FACTOR (TNFα) BY MONONUCLEAR CELLS (MC) OF HERPES SIMPLEX VIRUS (HSV) INFECTED NEONATES (NB) [PDF]

, 1987
Sandra Burchett, Kathev Mohan, Lawrence Corey, Christopher Wilson   +3 more
openalex   +1 more source

Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA

Advanced Science, EarlyView.
Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin, Runyu Cao, Xuemei Bai, Jiahua Yuan, Wanwei Sun, Yi Zheng, Xiaopeng Qi, Wei Zhao, Bingyu Liu, Chengjiang Gao   +9 more
wiley   +1 more source