Results 11 to 20 of about 308,094 (362)

TNFα induces matrix metalloproteinase-9 expression in monocytic cells through ACSL1/JNK/ERK/NF-kB signaling pathways

open access: yesScientific Reports, 2023
Studies have established the association between increased plasma levels of matrix metalloproteinase (MMP)-9 and adipose tissue inflammation. Tumor necrosis factor α (TNFα) was elevated in obesity and is involved in the induction of MMP-9 in monocytic ...
A. Al-Roub   +7 more
semanticscholar   +1 more source

At the Crossroads of TNFα Signaling and Cancer.

open access: yesCurrent Molecular Pharmacology, 2023
Tumor necrosis factor-alpha (TNFα) is a pleiotropic pro-inflammatory cytokine of the TNF superfamily. It regulates key cellular processes such as death, and proliferation besides its well-known role in immune response through activation of various ...
S. Manohar
semanticscholar   +1 more source

Inflammatory cytokines TNFα, IL-1β, and IL-6 are induced in endotoxin- stimulated microglia through different signaling cascades

open access: yesScience in progress, 2021
By using an animal model in which inflammatory cytokines are induced in lipopolysaccharide (LPS)-injected rat brain, we investigated the induction of tumor necrosis factor alpha (TNFα), interleukin-1beta (IL-1β), and IL-6.
Takashi Ishijima, K. Nakajima
semanticscholar   +1 more source

TNFα promotes oral cancer growth, pain, and Schwann cell activation

open access: yesScientific Reports, 2021
Oral cancer is very painful and impairs a patient’s ability to eat, talk, and drink. Mediators secreted from oral cancer can excite and sensitize sensory neurons inducing pain.
E. Salvo   +6 more
semanticscholar   +1 more source

TNFα secreted by glioma associated macrophages promotes endothelial activation and resistance against anti-angiogenic therapy

open access: yesActa Neuropathologica Communications, 2021
One of the most prominent features of glioblastoma (GBM) is hyper-vascularization. Bone marrow-derived macrophages are actively recruited to the tumor and referred to as glioma-associated macrophages (GAMs) which are thought to provide a critical role in
Qingxia Wei   +10 more
semanticscholar   +1 more source

Nigella sativa oil protects against cadmium-induced intestinal toxicity via promotion of anti-inflammatory mechanisms, mucin expression and microbiota integrity [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2022
Objective: This study examined the protective effects of Nigella sativa oil (NSO) on cadmium (Cd)-induced alterations affecting gut morphology and microbiota composition, as well as the involvement of mucus glycoprotein (MUC2) and immuno-inflammatory ...
Akinleye Akinrinde   +2 more
doaj   +1 more source

Regulation of NF-κB by PML and PML-RARα [PDF]

open access: yes, 2017
Promyelocytic Leukemia (PML) is a nuclear protein that forms sub-nuclear structures termed nuclear bodies associated with transcriptionally active genomic regions. PML is a tumour suppressor and regulator of cell differentiation.
Ahmed, Abrar   +8 more
core   +1 more source

Helicobacter pyloriinfection of human gastric epithelial cells induces IL-8 and TNFα, but not TGFβ1 mRNA [PDF]

open access: yesFEMS Immunology & Medical Microbiology, 2000
Helicobacter pylori (Hp) infection causes gastric ulcers and gastric carcinomas. The mechanisms of these diseases are not known but Hp induction of cytokines is believed to be involved. However, the profile as well as the involvement of cytokines induced by Hp infection is less clear.
N, Nakachi   +3 more
openaire   +2 more sources

Dynamics of Serum Cytokines During Resection Surgery for Malignant Neoplasms in the Lungs

open access: yesОбщая реаниматология, 2020
Purpose — to carry out a comparative assessment of inflammation based on evaluation of intraoperative and early postoperative dynamics of blood serum cytokines in pulmonary malignant neoplasm patients in different anesthesia and analgesia settings ...
A. O. Soloviev   +5 more
doaj   +1 more source

FGB, TNFα, IL-1β, LPL, ITGB3, and TGFB1 genes polymorphism in patients with recurrent myocardial infarction

open access: yesБюллетень сибирской медицины, 2021
The aim. To evaluate the association of fibrinogen (FGB), tumor necrosis factor α (TNFα), interleukin 1β (IL-1β), lipoprotein lipase (LPL), platelet glycoprotein (ITGB3), and transforming growth factor β (TGFB1) genes  with the incidence of recurrent ...
S. D. Mayanskaya   +6 more
doaj   +1 more source

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