Results 191 to 200 of about 308,094 (362)

Plasma levels of IL-6, IL-10, IL-18, TNFα under the conditions of tobacco intoxication and after treatment with aminophthalhydrazide

Медицинская иммунология
In response to damaging factors, a cascade of cytokines is released, triggering the processes of inflammation and fibrogenesis. The purpose of our study was to evaluate the levels of cytokines (IL-6, IL-10, IL-18, TNFα) in blood plasma under conditions ...
O. V. Alpidovskaya
doaj   +1 more source

Effect of JAK inhibitors on release of CXCL9, CXCL10 and CXCL11 from human airway epithelial cells [PDF]

, 2015
Barnes, PJ, Donnelly, LE, Fenwick, PS, Macedo, P   +3 more
core   +1 more source

Macrophage-Secreted TNFα and TGFβ1 Influence Migration Speed and Persistence of Cancer Cells in 3D Tissue Culture via Independent Pathways [PDF]

, 2016
Ran Li, Jess D. Hebert, Tara A. Lee, Hao Xing, Alexandra Boussommier-Calleja, Richard O. Hynes, Douglas A. Lauffenburger, Roger D. Kamm   +7 more
openalex   +1 more source

Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases

Cell, 2005
H. Kamata, Shino Honda, S. Maeda, Lufen Chang, H. Hirata, M. Karin   +5 more
semanticscholar   +1 more source

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

Advanced Science, EarlyView.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li, Xiaochen Zhang, Jiangwei Xia, Shuang Liu, Yushan Du, Sihan Li, Shukui Zhang, Yong Zhang, Fen Ji, Jianwei Jiao, Jingjing Zhang   +10 more
wiley   +1 more source

Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils [PDF]

, 2016
Simone Wicki, Ursina Gurzeler, W. Wei‐Lynn Wong, Philipp J. Jost, Daniel Bachmann, Thomas Kaufmann   +5 more
openalex   +1 more source

Dehydrocorydaline Accelerates Cell Proliferation and Extracellular Matrix Synthesis of TNFα-Treated Human Chondrocytes by Targeting Cox2 through JAK1-STAT3 Signaling Pathway [PDF]

, 2022
Yongqiang Sha, Beibei Zhang, Liping Chen, Chunli Wang, Tao Sun   +4 more
openalex   +1 more source

IL‐4/STAT6‐signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis

Advanced Science, EarlyView.
IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H, Salvers A, Piesker J, Buchholz S, Lange R, Ameling S, Steil L, Hammer E, Homuth G, Völker U, Bröker BM, Weiss FU, Sendler M, Glaubitz J   +13 more
wiley   +1 more source

Identification of a responsible promoter region and a key transcription factor, CCAAT/enhancer-binding protein ϵ, for up-regulation of PHGPx in HL60 cells stimulated with TNFα [PDF]

, 2007
Hiroyuki Hattori, Hirotaka Imai, Nozomu Kirai, Kazuhisa Furuhama, Osamu Satō, Kumiko Konishi, Yasuhito Nakagawa   +6 more
openalex   +1 more source

P911 The changes in the faecal microbiome and metabolome in Crohn’s disease after treatment with anti-TNFα antibodies are of secondary origin [PDF]

, 2023
Jakub Hurych, Anna Mascellani, Tereza Lerchová, Lucie Hlinakova, Michal Kubát, Hana Malcová, Dita Cebecauerová, Jan Schwarz, Eva Karásková, T Hecht, R Vyhnánek, L Ťoukálková, Vojtěch Dotlačil, K Kobrová, Anabela Cizkova, Rudolf Horváth, Jiří Bronský, Jaroslav Havlík, Ondřej Hradský, Ondřej Cinek   +19 more
openalex   +1 more source