Culture of Dendritic Cells from a Nonlymphoid Organ, the Thyroid Gland: Evidence for TNFα-Dependent Phenotypic Changes of Thyroid-Derived Dendritic Cells [PDF]
Karine Croizet+4 more
openalex +1 more source
Peripheral Biomarker Signatures in Rheumatoid Arthritis–Associated Interstitial Lung Disease
Objective Rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) is a significant cause of morbidity and mortality among patients with RA, yet effective risk stratification for RA‐ILD is lacking. We sought to characterize unique peripheral blood biomarker signatures in RA that could improve RA‐ILD discrimination beyond clinical and genetic ...
Austin M. Wheeler+18 more
wiley +1 more source
TNFα Receptor 1 and Not Receptor 2 Affect Annulus Fibrosus and Nucleus Pulposus Response to Cytokine Challenge in a Rat Model. [PDF]
Jacobsen TD+5 more
europepmc +1 more source
Objective JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but Tyk2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn disease, which highlights the complex role for JAK/STAT signaling in different inflammatory processes.
Sami Giryes+14 more
wiley +1 more source
Protective Effects of Extracts from Green Leaves and Rhizomes of <i>Posidonia oceanica</i> (L.) Delile on an In Vitro Model of the Human Blood-Brain Barrier. [PDF]
Abruscato G+8 more
europepmc +1 more source
SUBLETHAL HEMORRHAGIC SHOCK REDUCES TNFα PRODUCING CAPACITY IN DIFFERENT COMPARTMENTS
M. Ackermann+3 more
openalex +1 more source
Relationship between TNFα and IL10 release during cardiac operations and the development of apoptosis [PDF]
Ma Qing+7 more
openalex +1 more source
Gout and NLRP3 Inflammasome Biology
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilization, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal–induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley +1 more source
Gene expression profiles identify key factors in inflammatory odontoblastic dental pulp stem cell differentiation via TNFα/C5L2. [PDF]
Irfan M, Kim JH, Sreekumar S, Chung S.
europepmc +1 more source