Results 221 to 230 of about 254,881 (331)

Apoptosis in Cardiac Conditions Including Cirrhotic Cardiomyopathy. [PDF]

Int J Mol Sci
Yu F, Ryu DG, Yoon KT, Liu H, Lee SS.
europepmc   +1 more source

DEVELOPMENT OF A SELECTIVE INHIBITOR OF CYTOKINE-INDUCIBLE L-ARGININE TRANSPORT (CNI-1493) THAT BLOCKS MACROPHAGE PRODUCTION OF NO AND TNFα, AND PROTECTS AGAINST LPS LETHALITY.

, 1995
Marco E. Bianchi, Ona Bloom, Malcolm E. Meistrell, Peter Ulrich, Anthony Cerami, Kevin J. Tracey   +5 more
openalex   +1 more source

New Horizons for Multiple Sclerosis Therapy: 2025 and Beyond

Annals of Neurology, EarlyView.
The advances achieved against multiple sclerosis (MS) represent one of the great success stories of modern molecular medicine. The development of therapies with increasing selectivity and safety, guided by gains in understanding the fundamental immunology, neurobiology, genetics, and triggers of this disease, have broadened the traditional focus on ...
Joseph J. Sabatino Jr., Bruce A. C. Cree, Stephen L. Hauser   +2 more
wiley   +1 more source

TNFα Receptor 1 and Not Receptor 2 Affect Annulus Fibrosus and Nucleus Pulposus Response to Cytokine Challenge in a Rat Model. [PDF]

JOR Spine
Jacobsen TD, Yiantsos SO, Gansau J, Meyers J, Laudier D, Iatridis JC.   +5 more
europepmc   +1 more source

S phase dependence and involvement of NF-kappaB activating kinase to NF-kappaB activation by camptothecin22Abbreviations: ALLN, N-acetyl-leu-leu-norleucinal; AT, ataxia telangiectasia; CHX, cycloheximide; CPT, camptothecin; IκB, inhibitor kappa B; IKK, IκB kinase; MEKK1, mitogen-activated protein/ERK kinase kinase 1; NF-κB, nuclear factor kappa B; NIK, NF-κB-inducing kinase; P-IκBα, phosphorylated IκBα, and TNFα, tumor necrosis factor-α. [PDF]

, 2001
Yvette Habraken, Bernard Piret, Jacques Piette   +2 more
openalex   +1 more source

Cationic Nanoparticles Mitigate Chemotherapy‐Induced Peripheral Neuropathy

Advanced NanoBiomed Research, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN), caused by chemodrugs like paclitaxel (PTX), leads to severe neuropathic pain. This study evaluates PTX‐loaded PAMAM‐Chol nanoparticles (PTX‐NPs) to alleviate CIPN. PTX‐NPs achieve 99% drug‐loading efficiency, reduce neurotoxicity, and in murine models, decrease cold allodynia by 85% while restoring ...
Divya Bhansali, Rocco Latorre, Raquel Tonello, David Poolman, Suwan Ding, Brian L. Schmidt, Nigel W. Bunnett, Kam W. Leong   +7 more
wiley   +1 more source

Gene expression profiles identify key factors in inflammatory odontoblastic dental pulp stem cell differentiation via TNFα/C5L2. [PDF]

Front Genet
Irfan M, Kim JH, Sreekumar S, Chung S.
europepmc   +1 more source

Role of TNFα in regulation of myeloperoxidase expression in irradiated HL60 promyelocytic cells

, 2000
Misao Hachiya, Yoshiaki Osawa, Makoto Akashi   +2 more
openalex   +1 more source

Peripheral Biomarker Signatures in Rheumatoid Arthritis–Associated Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) is a significant cause of morbidity and mortality among patients with RA, yet effective risk stratification for RA‐ILD is lacking. We sought to characterize unique peripheral blood biomarker signatures in RA that could improve RA‐ILD discrimination beyond clinical and genetic ...
Austin M. Wheeler, Joshua F. Baker, Thomas R. Riley IV, Tate M. Johnson, Yangyuna Yang, Punyasha Roul, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Gail Kerr, Dana P. Ascherman, Paul Monach, Andreas Reimold, Scott Matson, Jill A. Poole, Michael J. Duryee, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +18 more
wiley   +1 more source

Protective Effects of Extracts from Green Leaves and Rhizomes of <i>Posidonia oceanica</i> (L.) Delile on an In Vitro Model of the Human Blood-Brain Barrier. [PDF]

Biology (Basel)
Abruscato G, Mauro M, Boucau MC, Arizza V, Vazzana M, Dehouck L, Gosselet F, Luparello C, Candela P.   +8 more
europepmc   +1 more source