Results 251 to 260 of about 308,094 (362)

Molecular determinants of TNFR1:TNFα binding and dynamics in a physiological membrane environment. [PDF]

Curr Res Struct Biol
Álvarez Sánchez E, Huet S, Téletchéa S.   +2 more
europepmc   +1 more source

Intratumoral Fusobacterium nucleatum Drives Cancer‐Associated Fibroblasts Enrichment and Immune Exclusion in Esophageal Squamous Cell Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
Fusobacterium nucleatum contributes to the progression of ESCC by inducing NF‐κB–mediated inflammatory signaling in tumor cells and promoting CAFs activation. Its presence may facilitate immune exclusion and tumor invasion through stromal remodeling. Furthermore, F.
Takashi Ofuchi, Qingjiang Hu, Kazuki Omachi, Kosuke Kanemitsu, Hajime Otsu, Yusuke Yonemura, Taro Tobo, Yoshifumi Baba, Masaaki Iwatsuki, Koshi Mimori   +9 more
wiley   +1 more source

The molecular mechanism of the adverse effects of the biological and small molecular drugs in the therapy of inflammatory skin diseases - psoriasis and atopic dermatitis. [PDF]

Ann Med
Lemiesz P, Nowowiejska-Purpurowicz J, Flisiak I.   +2 more
europepmc   +1 more source

Inadequate response to anti-TNFα therapy is associated with a gain-of-function TNFR2-R polymorphic variant in patients with psoriatic arthritis [PDF]

James Sullivan, Vandana Rai, Jennifer Harvey, Vincent Del Signore, Shashank Cheemalavagu, Jean Z. Lin, Sujay Subbayya Ithychanda, Jun Qin, Unnikrishnan M. Chandrasekharan, M. Elaine Husni   +9 more
openalex   +1 more source

Use of a Validated Online Calculator to Determine TB Progression Risk in Patients with Latent Tuberculosis Infection on TNFα Therapy [PDF]

, 2017
Ken Dekitani, Michael Scolarici, Soumya Chatterjee   +2 more
openalex   +1 more source

Real‐Time, Label‐Free Classification of Cell Death Pathways via Holotomography‐Based Deep Learning Framework

Advanced Intelligent Systems, EarlyView.
A 3D holotomography system coupled with a deep learning model distinguishes how cells die—apoptosis, necroptosis or necrosis—without any fluorescent labels. Training on refractive index maps of HeLa cells yields 97% accuracy and flags necroptosis hours before chemical dyes.
Minwook Kim, Wei Sun Park, Geon Kim, Sanggeun Oh, Jaephil Do, Juyeon Park, Jihwan Yu, Won Do Heo, YongKeun Park   +8 more
wiley   +1 more source

HuB serves as the central hub for connecting HuR-related mRNAs with translation machinery in inflammation. [PDF]

Commun Biol
Zhang J, Huang X, Tang Y, Zhong X, Wang J, Wei M, Han X, Ke Y, Ba X.   +8 more
europepmc   +1 more source

TNFα gene expression is induced in neurones after a hippocampal lesion

, 1994
Jean‐Léon Tchélingérian, Lionel Vignais, C. Jacque   +2 more
openalex   +2 more sources

Supplementary Figure 2 from ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth

, 2023
George A. Ward, Edward J. Lewis, Jong Sook Ahn, Christopher N. Johnson, John F. Lyons, Vanessa Martins, Joanne M. Munck, Sharna J. Rich, Tomoko Smyth, Neil T. Thompson, Pamela A. Williams, Nicola E. Wilsher, Nicola G. Wallis, Gianni Chessari   +13 more
openalex   +1 more source

Adropin modulates pancreatic cell proliferation and glutathione levels in an animal model of type 1 diabetes mellitus

Animal Models and Experimental Medicine, EarlyView.
Adropin is related to the energy homeostasis‐associated gene. It significantly increased glutathione reductase enzyme levels in the pancreas of experimental diabetic rats. Adropin may reduce the severity of diabetes and its complications. Cell proliferation in the exocrine is reduced after the administration of adropin.
Ifrah I. Ali, Crystal D'Souza, Abderrahim Nemmar, Shreesh Ojha, Ernest A. Adeghate   +4 more
wiley   +1 more source