Results 291 to 300 of about 308,094 (362)

iRhom2 regulates HMGB1 secretion to modulate inflammation and hepatocyte senescence in an in vitro model of ischemia-reperfusion injury. [PDF]

Cell Death Dis
Calligaris M, Perriera R, Carcione C, Miceli V, Pinto ML, Busà R, Amico G, Bulati M, Amato C, Pagano D, Conaldi PG, Scilabra SD, Pinzani M, Zito G.   +13 more
europepmc   +1 more source

The Citrullinated and MMP-degraded Vimentin Biomarker (VICM) Predicts Early Response to Anti-TNFα Treatment in Crohn’s Disease

, 2020
Joachim Høg Mortensen, Wouter T. van Haaften, M.A. Karsdal, Anne‐Christine Bay‐Jensen, Peter Olinga, Henning Grønbæk, Christian Lodberg Hvas, Tina Manon‐Jensen, Gerard Dijkstra, Anders Dige   +9 more
openalex   +2 more sources

Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα

Science immunology, 2017
Bo Sun, N. Dwivedi, Tyler J. Bechtel, J. Paulsen, A. Muth, M. Bawadekar, Gang Li, P. Thompson, M. Shelef, C. Schiffer, E. Weerapana, I. Ho   +11 more
semanticscholar   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Secreted mitochondrial aspartyl-tRNA synthetase (DARS2) regulates TNFα signaling. [PDF]

Physiol Rep
Johnson BS, Cornwell A, Farkas D, Yurtsever I, Joseph JA, Pradhan A, Farkas L, Londino JD, Bednash JS, Mallampalli RK.   +9 more
europepmc   +1 more source

Tumor necrosis factor alpha (TNFα) binding to A 75 kD receptor enhances proliferation of CACO-2 cells and is associated with increased sphingomyelinase activity

, 1995
T.L. O'Connor, Gary W. Varilek, Sudha Murthy, F. Jeffrey Field, Warren P. Bishop   +4 more
openalex   +1 more source

Statins Attenuate Activation of the NLRP3 Inflammasome by Oxidized LDL or TNFα in Vascular Endothelial Cells through a PXR-Dependent Mechanism

Molecular Pharmacology, 2017
Shaolan Wang, Xinya Xie, Ting Lei, Kang Zhang, Baochang Lai, Zihui Zhang, Y. Guan, Guangmei Mao, L. Xiao, Nanping Wang   +9 more
semanticscholar   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Off-Label Ustekinumab and Vedolizumab in Pediatric Anti-TNFα Refractory IBD: Therapeutic Drug Monitoring Insights from a Case Series. [PDF]

Pharmaceuticals (Basel)
Cheli S, Mosini G, Battini V, Carnovale C, Radice S, Lebiu M, Cattoni A, Zuin G, Clementi E.   +8 more
europepmc   +1 more source

Cytokines and chemokines in Mycobacterium tuberculosis infection [PDF]

, 2016
Cooper, Andrea, Domingo-Gonzalez, Racquel, Khader, Shabaana A, Prince, Oliver   +3 more
core   +2 more sources