Results 321 to 330 of about 254,881 (331)

Early and long-lasting protection from arthritis in tumour necrosis factor α (TNFα) transgenic mice vaccinated against TNFα

Annals of the Rheumatic Diseases, 2008
To evaluate the effect in mice with arthritis of active anti-tumour necrosis factor (TNF)alpha immunotherapy based on a keyhole limpet haemocyanin-human TNFalpha heterocomplex (hTNFalpha kinoid or TNFK) adjuvanted in incomplete Freund adjuvant. Immunotherapy was evaluated also with methotrexate.Human TNFalpha-transgenic mice received TNFK with or ...
Delavallée, Laure, Le Buanec, Hélène, Bessis, Natacha, Assier, Éric, Denys, Anne, Bizzini, Bernard, Zagury, Daniel, Boissier, Marie Christophe   +7 more
openaire   +3 more sources

Therapeutic pathomorphism of non-small cell lung cancer (NSCLC) as a result of neoadjuvant chemoimmunotherapy (nCIT) with tumor necrosis factor (TNFα1).

Journal of Clinical Oncology, 2018
e24323Background: The purpose of the study was to reveal morphological changes in tissues of NSCLC after various nPCT regimens.
Tamara G. Ayrapetova, Igor A. Leyman, A. S. Shogenov, Yuri Lazutin, Liubov Yu Vladimirova, Oleg N. Stateshny, Rukiyat Isaeva, S. G. Beleckiy, Sergey P. Pyltsin, M. Afaunov, Igor N. Turkin, Anna V. Chubaryan, M. A. Gappoeva, Pavel A. Anistratov   +13 more
openaire   +2 more sources

The alternate effects of anti-TNFα therapeutics and their role in mycobacterial granulomatous infection in Crohn’s disease

Expert Review of Anti-infective Therapy, 2017
Crohn's disease is an inflammatory bowel disease that has been debated to be associated with bacterial triggers such as Mycobacterium avium subspecies paratuberculosis (MAP). Standard treatment of Crohn's disease (CD) patients includes a family of immunomodulators and biologics such as Anti-Tumor Necrosis Factor alpha (Anti-TNFα).
Qasem, Ahmad, Naser, Abed Elrahman, Naser, Saleh A.   +2 more
openaire   +4 more sources

Post-resistance exercise ingestion of milk protein attenuates plasma TNFα and TNFr1 expression on monocyte subpopulations

Amino Acids, 2017
Attenuating TNFα/TNFr1 signaling in monocytes has been proposed as a means of mitigating inflammation. The purpose of this study was to examine the effects of a milk protein supplement on TNFα and monocyte TNFr1 expression. Ten resistance-trained men (24.7 ± 3.4 years; 90.1 ± 11.3 kg; 176.0 ± 4.9 cm) ingested supplement (SUPP) or placebo (PL ...
Adam J. Wells, Adam R. Jajtner, Alyssa N. Varanoske, David D. Church, Adam M. Gonzalez, Jeremy R. Townsend, Carleigh H. Boone, Kayla M. Baker, Kyle S. Beyer, Gerald T. Mangine, Leonardo P. Oliveira, David H. Fukuda, Jeffrey R. Stout, Jay R. Hoffman   +13 more
openaire   +4 more sources

Disseminated tuberculosis after anti-TNFα therapy for Crohn\'s disease

2015
Clinical History: Patient with long-standing history of Crohn’s disease (CD) including partial colectomy, treated with adalimumab for four months due to steroid-refractory disease. Currently hospitalized with malaise, weight loss, mucohaemorrhagic diarrhoea, persistent h...
openaire   +1 more source

Lysyl Oxidase is a Novel Fibrostenotic Indicator in Eosinophilic Esophagitis Induced VIA the TNFΑ-TGFÎ' Axis in the Epithelial-Fibroblast Crosstalk

Gastroenterology, 2017
Kelly A. Whelan, Prasanna M. Chandramouleeswaran, Maureen DeMarshall, Amanda B. Muir, Alain Benitez, Jonathan M. Spergel, Antonella Cianferoni, Gary W. Falk, Yuta Kasagi, Jonathan Kluger, Fiona Gambanga, Hiroshi Nakagawa, Jonathan Gross   +12 more
openaire   +2 more sources

The Fecal Microbiome as a Tool for Monitoring and Predicting Response Outcomes in Ustekinumab-Treated, Anti-TNFî‘ Refractory Crohn’s Disease Patients: Results from the Certifi Study

Gastroenterology, 2017
Calixte S. Monast, Patrick D. Schloss, Matthew K. Doherty, Charles C. Koumpouras, Shannon Telesco, Carrie Brodmerkel   +5 more
openaire   +2 more sources

Production of nitric oxide is not necessary for the mycobacteriostatis induced in murine macrophages by IFNγ and TNFα

Immunology Letters, 1997
openaire   +1 more source

Activation of protein kinase C (PKC) is critical for production of proinflammatory cytokines (TNFα, IL-1β, IL-6)

Immunology Letters, 1997
openaire   +1 more source

Interleukin-6 production by human liver (myo)fibroblasts in culture. Evidence for a regulatory role of LPS, IL-1β and TNFα

Journal of Hepatology, 1995
openaire   +1 more source