Results 351 to 360 of about 308,094 (362)

Early and long-lasting protection from arthritis in tumour necrosis factor α (TNFα) transgenic mice vaccinated against TNFα

Annals of the Rheumatic Diseases, 2008
Objective: To evaluate the effect in mice with arthritis of active anti-TNFα immunotherapy based on a keyhole limpet hemocyanin-human TNFα heterocomplex (hTNFα kinoid or TNFK) adjuvanted in incomplete Freund adjuvant. Immunotherapy was evaluated also with methotrexate.
Delavallée, Laure, Le Buanec, Hélène, Bessis, Natacha, Assier, Éric, Denys, Anne, Bizzini, Bernard, Zagury, Daniel, Boissier, Marie Christophe   +7 more
openaire   +1 more source

Therapeutic pathomorphism of non-small cell lung cancer (NSCLC) as a result of neoadjuvant chemoimmunotherapy (nCIT) with tumor necrosis factor (TNFα1).

Journal of Clinical Oncology, 2018
e24323Background: The purpose of the study was to reveal morphological changes in tissues of NSCLC after various nPCT regimens.
Yuri Lazutin, Sergey P. Pyltsin, Tamara G. Ayrapetova, Pavel A. Anistratov, Igor A. Leyman, Anna V. Chubaryan, Igor N. Turkin, Oleg N. Stateshny, A. S. Shogenov, Liubov Yu Vladimirova, M. A. Gappoeva, S. G. Beleckiy, M. Afaunov, Rukiyat Isaeva   +13 more
openaire   +1 more source

Protective role of nitric oxide in the TNFα-mediated hepatic microvascular inflammatory response following acute ethanol ingestion

Hepatology Research, 2000
Abstract Gut-drived endotoxin is thought to be involved in the pathogenesis of alcoholic liver disease. Nitric oxide (NO) has a protective function in attenuating hepatic injury elicited by endotoxin and is suspected to play a role in the hepatic microvascular responses induced following alcohol ingestion. As a result, the role of NO and the possible
openaire   +1 more source

Incidence and Clinical Impact of Anti-TNFα Treatment of Severe Immune Checkpoint Inhibitor-induced Colitis in Advanced Melanoma: The Mecolit Survey.

Journal of immunotherapy, 2019
Immune checkpoint inhibitors (ICI) significantly improve overall survival (OS) in patients with advanced melanoma, but immune-related colitis may occur and warrant anti-tumor necrosis factor α (TNFα) treatment in severe forms.
C. Lesage, C. Longvert, S. Prey, S. Maanaoui, B. Dréno, L. Machet, O. Zehou, N. Kramkimel, G. Jeudy, F. Skowron, F. Aubin, L. Visseaux, S. Mansard, O. Dereure, F. Lesage, B. Guillot   +15 more
semanticscholar   +1 more source

Disseminated tuberculosis after anti-TNFα therapy for Crohn\'s disease

2015
Clinical History: Patient with long-standing history of Crohn’s disease (CD) including partial colectomy, treated with adalimumab for four months due to steroid-refractory disease. Currently hospitalized with malaise, weight loss, mucohaemorrhagic diarrhoea, persistent h...
openaire   +1 more source

Lysyl Oxidase is a Novel Fibrostenotic Indicator in Eosinophilic Esophagitis Induced VIA the TNFΑ-TGFÎ' Axis in the Epithelial-Fibroblast Crosstalk

Gastroenterology, 2017
Yuta Kasagi, Fiona Gambanga, Alain Benitez, Kelly A. Whelan, Jonathan Kluger, Jonathan Gross, Prasanna Chandramouleeswaran, Jonathan Spergel, Antonella Cianferoni, Maureen DeMarshall, Gary W. Falk, Hiroshi Nakagawa, Amanda B. Muir   +12 more
openaire   +1 more source

The Fecal Microbiome as a Tool for Monitoring and Predicting Response Outcomes in Ustekinumab-Treated, Anti-TNFî‘ Refractory Crohn’s Disease Patients: Results from the Certifi Study

Gastroenterology, 2017
Matthew K. Doherty, Charles Koumpouras, Shannon Telesco, Calixte S. Monast, Carrie Brodmerkel, Patrick D. Schloss   +5 more
openaire   +1 more source

Production of nitric oxide is not necessary for the mycobacteriostatis induced in murine macrophages by IFNγ and TNFα

Immunology Letters, 1997
openaire   +1 more source

Activation of protein kinase C (PKC) is critical for production of proinflammatory cytokines (TNFα, IL-1β, IL-6)

Immunology Letters, 1997
openaire   +1 more source

Interleukin-6 production by human liver (myo)fibroblasts in culture. Evidence for a regulatory role of LPS, IL-1β and TNFα

Journal of Hepatology, 1995
openaire   +1 more source