Results 31 to 40 of about 253,142 (331)

Candida albicans Yeast, Pseudohyphal, and Hyphal Morphogenesis Differentially Affects Immune Recognition [PDF]

, 2017
The authors thank Amy Whittington for preliminary experiments on in vitro induction of pseudohyphae and Mihai Netea for discussions. The authors also thank Michael Weig for the pga29 strains. Funding NG and AW were supported by the Wellcome Trust (086827,
Bailey, Bates, Bates, Beaussart, Berman, Birse, Blasi, Brown, Bulawa, Calera, Cambi, Chen, Chen, Cheng, Cheng, Chiani, Courjol, Dalle, De Boer, Dennehy, d’Ostiani, Endres, Erwig, Fidel, Gantner, Gantner, Ghannoum, Gow, Gow, Gow, Gow, Gow, Gudlaugsson, Harris, Heinsbroek, Hobson, Hoebe, Hornby, Hornby, Hosseinzadeh, Jackson, Jouault, Kohatsu, Kullberg, Kullberg, Lee, Linden, Lo, Lu, Matuschak, McKenzie, Medzhitov, Merson-Davies, Mora-Montes, Mora-Montes, Moyes, Moyes, Moyes, Moyes, Munro, Murad, Netea, Netea, Netea, Pappas, Plaine, Rubin-Bejerano, Saville, Sellam, Sudbery, Sudbery, Sundstrom, Torosantucci, Van De Veerdonk, Van Der Graaf, Vavala, Wagener, Wheeler, Zhao, Zheng   +79 more
core   +2 more sources

Ultraviolet Radiation Effects on Human Keratinocyte ICAM-1 Expression: UV-Induced Inhibition of Cytokine-Induced ICAM-1 mRNA Expression Is Transient, Differentially Restored for IFNγ Versus TNFα, and Followed by ICAM-1 Induction Via a TNFα-Like Pathway

Journal of Investigative Dermatology, 1992
Human keratinocytes (KC) during the course of inflammatory dermatoses strongly express the surface molecule ICAM-1, which plays an important role in the generation of the epidermal inflammatory infiltrate by mediating leukocyte-keratinocyte interactions.
Erwin Schöpf, Thomas A. Luger, Wolfgang Czech, Uwe Trefzer, Alexander Kapp, Frauke Parlow, Jean Krutmann   +6 more
openaire   +3 more sources

Brain Protection from Stroke with Intravenous TNFα Decoy Receptor-Trojan Horse Fusion Protein [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2012
Tumor necrosis factor (TNF)- α is produced in brain in response to acute cerebral ischemia, and promotes neuronal apoptosis. Biologic TNF inhibitors (TNFIs), such as the etanercept, cannot be developed as new stroke treatments because these large molecule drugs do not cross the blood–brain barrier (BBB).
Sumbria, Rachita K., Boado, Ruben J., Pardridge, William M.   +2 more
openaire   +4 more sources

A Unique Case of Acute Respiratory Distress Syndrome Secondary to Rheumatoid Lung Disease With Administration of Anti-Tumor Necrosis Factor Alpha (TNFα) Agent

Cureus, 2023
Patients with rheumatoid arthritis (RA) may experience complications directly from the disease process or from immune-modulating agents used to treat RA. Adalimumab is a recombinant human monoclonal antibody directed against tumor necrosis factor alpha (TNFα) which has been increasingly used in the management of inflammatory and autoimmune diseases ...
Sherlock, Daniel, Ahdi, Hardeep S, Mehta, Raju   +2 more
openaire   +3 more sources

EFFECTS OF SYNTETIC CANNABINOID RECEPTOR LIGANDS WIN 55.212-2 AND ANANDAMID UPON IN VITRO ACTIVITY OF IMMUNOCOMPETENT CELLS

Медицинская иммунология, 2014
. Ability of cannabinoid receptor ligands WIN 55.212-2 and anandamid to inhibit synthesis of TNFα and IL-8 was studied in healthy donors and men with allergic disorders.
E. G. Lobanova
doaj   +1 more source

Correlation of Lipopolysaccharide Endotoxin Level in Cotton Dust with the Increase of TNFα Level and the Decline of Lung Function in Cotton Spinning Factory Workers [PDF]

, 2014
Lipopolysaccharide (LPS) endotoxin contained in cotton dust may cause airway inflammation and decline of lung function when inhaled, which eventually leads to respiratory symptoms.
Indahwati, L. (Leli), Keman, S. (Soedjajadi), Noviarmi, F. S. (Fadilatus)   +2 more
core   +2 more sources

PRODUCTION OF PROINFLAMMATORY CYTOKINES AND ALPHA-2-MACROGLOBULIN BY PERIPHERAL BLOOD CELLS IN THE PATIENTS WITH COLORECTAL CANCER

Медицинская иммунология, 2016
Colorectal cancer (CRC) is the third most common cancer worldwide, being quite complicated, with respect to diagnostics and postoperative prognosis. Proinflammatory cytokines are shown to be involved into CRC pathogenesis. However, the changes in alpha-2-
V. N. Zorina, N. V. Promzeleva, N. A. Zorin, T. G. Ryabicheva, R. M. Zorina   +4 more
doaj   +1 more source

Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation. [PDF]

, 2017
Atherosclerosis impacts arteries where disturbed blood flow renders the endothelium susceptible to inflammation. Cytokine activation of endothelial cells (EC) upregulates VCAM-1 receptors that target monocyte recruitment to atherosusceptible regions ...
Bailey, Keith A, Haj, Fawaz G, Passerini, Anthony G, Simon, Scott I   +3 more
core   +1 more source

Crystal structure of TNFα complexed with a poxvirus MHC-related TNF binding protein [PDF]

Nature Structural & Molecular Biology, 2009
The poxvirus 2L protein binds tumor necrosis factor-alpha (TNFalpha) to inhibit host antiviral and immune responses. The 2.8-A 2L-TNFalpha structure reveals three symmetrically arranged 2L molecules per TNFalpha trimer. 2L resembles class I major histocompatibility complex (MHC) molecules but lacks a peptide-binding groove and beta2-microglobulin light
Yang, Zhiru, West, Anthony P., Jr., Bjorkman, Pamela J.   +2 more
openaire   +5 more sources

Genetic predisposition of TNFα gene polymorphism in South-Indian Migraineurs and meta-analysis

Frontiers in Bioscience-Elite, 2021
Migraine (Mg) is a multifaceted neurovascular disorder caused by genetic and several environmental etiologies. We have implemented a case-control study of TNFα gene polymorphism in 212 Mg patients and 218 healthy controls utilizing the ARMS-PCR technique,
Pallavi Kesavan, Aiswarya Padmaja Satheesh, Rehman Syed Rasheed Akram Husain, Umamaheshwari Veerappan, Subramaniyan Kannaian, Shiek SSJ Ahmed, Ramakrishnan Veerabathiran   +6 more
doaj   +1 more source