MCP‐induced protein 1 suppresses TNFα‐induced VCAM‐1 expression in human endothelial cells [PDF]
Endothelial inflammation plays a critical role in the development and progression of cardiovascular disease, albeit the mechanisms need to be fully elucidated. We here report that treatment of human umbilical vein endothelial cells (HUVECs) with tumor necrosis factor (TNF) α substantially increased the expression of MCP‐induced protein 1 (MCPIP1 ...
Yan Cai+8 more
openaire +4 more sources
Inflammation plays a role in the pathogenesis of COPD by interfering with the protease/antiprotease and oxidant/antioxidant balance. There is no adequate data about the relationship between oxidative stress biomarkers and FEV1 values in stable COPD ...
Sumeyye Alparslan Bekir
doaj +1 more source
PRAS40 suppresses atherogenesis through inhibition of mTORC1-dependent pro-inflammatory signaling in endothelial cells [PDF]
Endothelial pro-inflammatory activation plays a pivotal role in atherosclerosis, and many pro-inflammatory and atherogenic signals converge upon mechanistic target of rapamycin (mTOR).
Althoff, Till F.+14 more
core +1 more source
Background: Recurrent diabetic maculopathy (DMP) and diabetic macular edema (DME) may develop in the early or late period even after an advanced vitreoretinal procedure.
Iu. O. Panchenko+5 more
doaj +1 more source
Visceral adipose tissue activated macrophage content and inflammatory adipokine secretion is higher in pre-eclampsia than in healthy pregnancy [PDF]
Obesity increases preeclampsia risk. Adipose tissue inflammation may contribute to the clinical syndrome of pre-eclampsia. We compared adipose tissue macrophage infiltration and release of pro-inflammatory adipokines in pre-eclampsia and healthy ...
Bray, Jack+6 more
core +1 more source
Evaluation of Anti-Inflammatory Effect of Chicory Extract on Inflammatory Factors of Interleukin 8 and TNFα in Rats with Polycystic Ovary Syndrome [PDF]
Background & Objective: Polycystic ovary disease is an indicator of inflammatory factors caused by ovarian inflammation and an increase in the number of ovarian cysts.
amene Shahverdi Shahraki+2 more
doaj
T-type Ca2+ channels are required for enhanced sympathetic axon growth by TNFα reverse signalling [PDF]
Tumour necrosis factor receptor 1 (TNFR1)-activated TNFα reverse signalling, in which membrane-integrated TNFα functions as a receptor for TNFR1, enhances axon growth from developing sympathetic neurons and plays a crucial role in establishing ...
Lilian Kisiswa+6 more
doaj +1 more source
Changes in myoblast responsiveness to TNFα and IL-6 contribute to decreased skeletal muscle mass in intrauterine growth restricted fetal sheep1 [PDF]
National Institute of General Medical Sciences [1P20GM104320]; Nebraska Agricultural Experiment Station; Hatch Act [NEB-26-224]; Hatch Multistate Research capacity funding program through the USDA National Institute of Food and Agriculture [NEB-26-226, NEB-26-225]
Posont, Robert J.+3 more
openaire +3 more sources
LDL receptor-related protein-1 regulates NFκB and microRNA-155 in macrophages to control the inflammatory response [PDF]
LDL receptor-related protein-1 (LRP1) is an endocytic and cell-signaling receptor. In mice in which LRP1 is deleted in myeloid cells, the response to lipopolysaccharide (LPS) was greatly exacerbated.
Azmoon, Pardis+5 more
core +1 more source
Ekstrak daun sirsak (Annona muricata) mengandung antioksidan seperti flavanoid, acetogenins yang memiliki peran sebagai antiplasmodium secara in vitro. Penelitian ini bertujuan menguji pengaruh ekstrak etanol daun sirsak terhadap penurunan kadar Tumor Necrosis Fakctor-alpha (TNFα) dan peningkatan kadar Nitric Oxide (NO) pada limpa mencit Swiss betina ...
Fransisca Prameshinta H+3 more
openaire +2 more sources