Results 41 to 50 of about 308,094 (362)

DIAGNOSTIC AND PREDICTIVE VALUE OF TNF Α, IL-8 AND IL-6 ASSAYS IN THE PATIENTS WITH MYCOPLASMA-ASSOCIATED PNEUMONIAS

Медицинская иммунология, 2014
. We have observed 128 patients with non-nosocomial pneumonias. Bacterial microflora was isolated in 22.6 per cent of entire group. 17 per cent of the samples were seropositive for Mycoplasma pneumoniae, along with detectable DNA specific for this causal
T. I. Dolgikh, V. I. Sovalkin, I. V. Menshchikova   +2 more
doaj   +1 more source

Anthocyanins inhibit tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity [PDF]

, 2017
An increased permeability of the intestinal barrier is proposed as a major event in the pathophysiology of conditions characterized by chronic gut inflammation.
Anderson, Maureen, Cremonini, Eleonora, Fraga, César Guillermo, Hester, Shelly N., Mastaloudis, Angela, Oteiza, Patricia Isabel, Verstraeten, Sandra Viviana, Waterhouse, Andrew L., Wood, Steven M.   +8 more
core   +1 more source

Pivotal Role of Both TNF-α 238G/A and TCF7L2 C/T Gene Polymorphisms in Type 2 Diabetes

Open Access Macedonian Journal of Medical Sciences, 2020
Single nucleotide polymorphism (SNP) studies in the promoter region of tumor necrosis factor-alpha (TNF-α (238)) have suggested its role in increased insulin resistance and also in the progression from prediabetes to type 2 diabetes (T2DM). It has been reported that genetic variations in the promoter region regulate TNF-α production and transcription ...
El Hini, Sahar H., Ahmed, Amira Taha Zaki, Hamed, Eglal MS., Mahmoud, Yehia Z., Eldin, Amel Mahmoud Kamal, Abdelghany, Hend M.   +5 more
openaire   +3 more sources

Differential roles of TNFα-TNFR1 and TNFα-TNFR2 in the differentiation and function of CD4+Foxp3+ induced Treg cells in vitro and in vivo periphery in autoimmune diseases

Cell Death and Disease, 2019
Tumor Necrosis Factor (TNF) α is a multifunctional cytokine with pro-inflammatory and anti-inflammatory characteristics. Increasing evidence suggests that thymus-derived, natural regulatory T cells (nTreg) express a remarkably high level of TNF Receptor ...
Sujuan Yang, Chichu Xie, Ye Chen, Julie Wang, Xiaoqing Chen, Zhengqi Lu, Rayford R. June, S. Zheng   +7 more
semanticscholar   +1 more source

Association of TNF-α-308G/A and IL-18 Polymorphisms with risk of HPV infection among sexually active women in Burkina Faso

Biomolecular Concepts, 2020
Human papillomavirus (HPV) infection is the most common sexually transmitted infection worldwide. Persistence infection can lead to the development of cervical cancer potentially due to some genetic factors such as polymorphisms in regulatory and coding ...
Traore Ina M. A., Zohoncon Théodora M., Djigma Florencia W., Compaore T. Rebeca, Traore Yves, Simpore Jacques   +5 more
doaj   +1 more source

Immunological aspects of the use of melatonin in experimental thermal trauma

Медицинская иммунология, 2023
The prevalence of thermal trauma, the high risk of infectious and non-infectious short- and long- term complications, and the limited effectiveness of the therapeutic approaches used are prerequisites for the search and pathogenetic justification of new ...
M. V. Osikov, A. A. Ageeva, M. S. Boyko, Yu. I. Ageev   +3 more
doaj   +1 more source

Concurrent therapy with immune checkpoint inhibitors and TNFα blockade in patients with gastrointestinal immune-related adverse events

Journal of Immunotherapy for Cancer, 2019
BackgroundImmune checkpoint inhibitors (ICI) have demonstrated remarkable efficacy as cancer therapeutics, however, their use remains limited due to the development of immune related adverse events (irAEs).
Y. Badran, J. Cohen, P. Brastianos, A. Parikh, T. Hong, M. Dougan   +5 more
semanticscholar   +1 more source

TNFα and Reactive Oxygen Signaling in Vascular Smooth Muscle Cells in Hypertension and Atherosclerosis.

American Journal of Hypertension, 2020
Hypertension and atherosclerosis, the predecessors of stroke and myocardial infarction, are chronic vascular inflammatory reactions. Tumor necrosis factor alpha (TNFα), the "master" pro-inflammatory cytokine, contributes to both the initiation and ...
F. Lamb, Hyehun Choi, Michael R Miller, Ryan J. Stark   +3 more
semanticscholar   +1 more source

ACSL1 Regulates TNFα-Induced GM-CSF Production by Breast Cancer MDA-MB-231 Cells

Biomolecules, 2019
Overexpression of granulocyte-macrophage colony-stimulating factor (GM-CSF) in different types of cancer is associated with tumor growth and progression.
Reeby Thomas, Fatema Al-Rashed, Nadeem Akhter, Fahd Al-Mulla, Rasheed Ahmad   +4 more
doaj   +1 more source

Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes. [PDF]

, 2018
Glaucoma is characterized by a progressive loss of retinal ganglion cells and their axons, but the underlying biological basis for the accompanying neurodegeneration is not known.
Bu, Jung Hyun, Ellisman, Mark H, Jeong, Seung Won, Ju, Won-Kyu, Kim, Keun-Young, Nam, Hye Seung, Park, Tae Lim, Shim, Myoung Sup, Weinreb, Robert N   +8 more
core   +2 more sources