Results 81 to 90 of about 308,094 (362)

APOPTOSIS OF BLOOD LYMPHOCYTES IN THE PATIENTS WITH AUTOIMMUNE THYROID DISORDERS

Медицинская иммунология, 2014
. This article presents results of apoptosis detection among blood lymphocytes from the patients with autoimmune thyroid disorders, i.e., autoimmune thyroiditis (AIT) at euthyroid and hypothyroid stages, and in diffuse toxic goiter (DTG).
O. I. Urazova, E. B. Kravets, V. V. Novitsky, A. V. Rogaleva, T. E. Budkina, O. A. Sinyukova, Yu. V. Nedossekova, V. N. Kuznetsova   +7 more
doaj   +1 more source

EFFECT OF DATE FRUIT (PHOENIX DACTYLIFERA L.) EXTRACT ON TNFα LEVELS AND BRAIN WEIGHT OF ALZHEIMER’S MODEL RATS

Malang Neurology Journal, 2021
Background: Alzheimer's disease (AD) is a  neurodegenerative disorder marked by brain inflammation resulted in structural damage and brain dysfunction. Tumor necrosis factor α (TNFα) is a cytokine that plays an important role in inflammation.
Elita Marintan, Brian Wasita, Adi Magna
doaj   +1 more source

IL-1β and TNFα Differentially Influence NF-κB Activity and FasL-Induced Apoptosis in Primary Murine Hepatocytes During LPS-Induced Inflammation

Frontiers in Physiology, 2019
Macrophage-derived cytokines largely influence the behavior of hepatocytes during an inflammatory response. We previously reported that both TNFα and IL-1β, which are released by macrophages upon LPS stimulation, affect Fas ligand (FasL)-induced ...
Julia Rex, Anna Lutz, Laura Faletti, U. Albrecht, Mariam Thomas, J. Bode, C. Borner, O. Sawodny, I. Merfort   +8 more
semanticscholar   +1 more source

Effectiveness and safety of baricitinib for juvenile idiopathic arthritis associated uveitis or chronic anterior antinuclear antibody positive uveitis

Arthritis Care &Research, Accepted Article.
Objectives Evaluate the efficacy and safety of baricitinib in paediatric patients with active JIA‐U or chronic anterior ANA‐positive uveitis, who had an inadequate response to MTX or bDMARDs. Methods JUVE‐BRIGHT was an open‐label, active‐controlled, Phase‐3 multicentre trial which utilized a novel design, including 1:1 randomization to an active ...
Athimalaipet V. Ramanan, Catherine M. Guly, Gabriele Simonini, Stuart Keller, Priyanka Sen, Thorsten Holzkaemper, Joana Araújo, Pierre Quartier   +7 more
wiley   +1 more source

Risk Factors for Prostate Volume Progression After Prostate-Transurethral Resection

Research and Reports in Urology, 2020
Gede Wirya Kusuma Duarsa,1 Daniel Oktavianus Dau,1 Ida Bagus Putra Pramana,1 Pande Made Wisnu Tirtayasa,1 I Wayan Yudiana,1 Kadek Budi Santosa,1 Anak Agung Gde Oka,1 Tjokorda Gde Bagus Mahadewa,1 Christopher Ryalino2 1Department of Surgery, Faculty of ...
Duarsa GWK, Dau DO, Pramana IBP, Tirtayasa PMW, Yudiana IW, Santosa KB, Oka AAG, Mahadewa TGB, Ryalino C   +8 more
doaj  

CD4+ Th1 to the rescue in HER-2+ breast cancer

OncoImmunology, 2019
HER2 overexpression leads to downregulation of MHC class-I. CD4+ Th1 cytokines, IFNγ and TNFα, and monoclonal antibodies, trastuzumab and pertuzumab, restore MHC class-I expression, and enable CD8+ recognition and cytolysis.
Lea Lowenfeld, Shuwen Xu, Brian J. Czerniecki   +2 more
doaj   +1 more source

CLINICO-IMMUNOLOGIC AND CYTOGENETIC ASPECTS OF PATHOGENESIS IN SPASTIC INFANTILE CEREBRAL PARALYSIS

Медицинская иммунология, 2014
. Over recent years of studies in infantile cerebral paralysis (ICP), the changes in periventricular area are given great importance, especially, periventricular leukomalacia. An immunopathological process may define the prenatal brain damage.
D. D. Gaynetdinova, L. Z. Gaysina, R. F. Khakimova   +2 more
doaj   +1 more source

Kinase-independent function of RIP1, critical for mature T-cell survival and proliferation. [PDF]

, 2016
The death receptor, Fas, triggers apoptotic death and is essential for maintaining homeostasis in the peripheral lymphoid organs. RIP1 was originally cloned when searching for Fas-binding proteins and was later shown to associate also with the signaling ...
Bertin, John, Cai, Yubo, Dowling, John P., Gough, Peter J., Zhang, Jianke   +4 more
core   +2 more sources

Evaluation of a novel EHR sidecar application to display RA clinical outcomes during clinic visits: results of a stepped‐wedge cluster randomized pragmatic trial

Arthritis Care &Research, Accepted Article.
Objective We developed a novel EHR sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk, Jing Li, Cathy Nasrallah, Cherish Wilson, Alicia Hamblin, Christine Hariz, Cammie Young, Stephen Shiboski, Emma Kersey, Mary Nakamura, Judith F. Ashouri, Mehrdad Matloubian, Andrew J. Gross, Jennifer Barton, Beth Berrean, Jonathan Prugh, Jinoos Yazdany   +16 more
wiley   +1 more source

ROLE OF CYTOKINE-MEDIATED MECHANISMS IN DEVELOPMENT OF POST-TRAUMATIC MANDIBULAR OSTEOMYELITIS

Медицинская иммунология, 2019
Osteomyelitis of the lower jaw is one of the urgent problems of modern medicine. There are many reasons for the evolvement of purulent necrotic processes of the jaw bones, including the role of disorders in the systems of innate and adaptive immunity ...
E. V. Paskova, E. V. Markelova, K. I. Shakhgeldyan, B. I. Geltser, A. B. Kriger   +4 more
doaj   +1 more source