Results 81 to 90 of about 151,737 (271)

Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

open access: yesAdvanced Science, EarlyView.
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang   +16 more
wiley   +1 more source

Dendritic cells generated from induced pluripotent stem cells and by direct reprogramming of somatic cells

open access: yesEuropean Journal of Immunology, Volume 52, Issue 12, Page 1880-1888, December 2022., 2022
Somatic cells (fibroblasts, dendritic cells, T cells) are reprogrammed into induced pluripotent stem cells (iPS cells) with specific transcription factors. iPS cells are then differentiated into iPS cell‐derived DC (ipDC) with DC inducing cytokines. Fibroblasts are directly reprogrammed into induced DC (iDC) by DC specific transcription factors (direct
Niclas Flosdorf, Martin Zenke
wiley   +1 more source

CONTENTS OF CYTOKINES IN BLOOD OF THE PATIENTS WITH LOCAL FROSTBITES

open access: yesМедицинская иммунология, 2014
. Cytokines provide important connecting links between immunity, blood clotting, and nonspecific resistance that become altered in local frostbites. The aim of study was to determine the contents of cytokines in blood of patients with local frostbites at
K. G. Shapovalov   +4 more
doaj   +1 more source

Label‐Free Dual‐Modal Photoacoustic/Ultrasound Localization Imaging for Studying Acute Kidney Injury

open access: yesAdvanced Science, EarlyView.
This work develops a 3D label‐free photoacoustic/super‐resolution ultrasound imaging system as a comprehensive non‐invasive tool for acute kidney injury (AKI) study. This technique visualizes the intricate structure of renal microvessels and provides critical physiological insights, including renal hemodynamics and oxygenation.
Shensheng Zhao   +5 more
wiley   +1 more source

Flt3L, LIF, and IL‐10 combination promotes the selective in vitro development of ESAMlow cDC2B from murine bone marrow

open access: yesEuropean Journal of Immunology, Volume 52, Issue 12, Page 1946-1960, December 2022., 2022
In vitro culture of murine bone marrow cells in Flt3L + LIF + IL‐10 promotes CD11b+ ESAMlow cDC2B subset generation from CDP but blocks cDC1 and pDC development. Flt3L alone or combined does not induce cDC2A generation in vitro. Abstract The development of two conventional dendritic cells (DC) subsets (cDC1 and cDC2) and the plasmacytoid DC (pDC) in ...
Laura Cyran   +8 more
wiley   +1 more source

CONTENTS OF CYTOKINES AND LACTOFERRIN IN ONCOLOGICAL PATIENTS

open access: yesМедицинская иммунология, 2014
. The purpose of present work was to study the peculiarities of cytokine production in patients with malignant tumors, as exemplified by lymphoma and malignant melanoma.
T. I. Dolgikh   +2 more
doaj   +1 more source

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

open access: yesAdvanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang   +12 more
wiley   +1 more source

Effects of altered salt intake and diet on cytokines in humans: A 20‐week randomized cross‐over intervention study

open access: yesEuropean Journal of Immunology, Volume 53, Issue 1, January 2023., 2023
The effect of habitual Western diet and salt‐reduced diet on the levels of systemic blood cytokines was analyzed in a placebo‐controlled nutritional intervention study. The results showed that reduced salt intake did not alter the concentrations of any of the analyzed 34 cytokines in blood.
Teemu Niiranen   +4 more
wiley   +1 more source

PROMOTER REGION rs1800629 TNFα POLYMORPHISM AND ITS INFLUENCE ON TUMOR NECROSIS FACTOR ALPHA CONCENTRATION IN BLOOD OF HEALTHY INDIVIDUALS AND PATIENTS WITH ERYSIPELAS

open access: yesМедицинская иммунология, 2018
Erysipelas is an actual problem of health care. It is characterized by consistently high morbidity, excepted tendency to recur, reduced the life quality and took important place in the structure of temporary disability.
A. S. Emelyanov   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy