Results 121 to 130 of about 948,306 (261)

TNF-α levels in all acutely admitted patients.

open access: yes, 2019
Serum TNF-α levels were significantly higher in agitated patients compared to non-agitated patients (21.87 ± 17.96 vs 14.94 ± 18.86 pg/mL). Data are expressed as median ± 95% confidence interval. **p = 0.004.
Arne Vaaler (525065)   +3 more
core   +1 more source

Protein‐Nanoarchitectures for Low‐Field Intracellular Electro‐Immunomodulation

open access: yesAdvanced Functional Materials, EarlyView.
DHQ‐SDH‐mediated binding of AuNPs drives the formation of interconnected, chain‐like nanoarchitectures with enhanced electrical conductivity. These conductive assemblies undergo macrophage uptake and enable low‐field electrical stimulation, promoting M1‐to‐M2 phenotypic switching with decreased iNOS and increased CD206 expression. Such protein‐mediated
Viktoriya Pakharenko   +7 more
wiley   +1 more source

TNF-α-dependent loss of monolayer resistance in HDMEC does not depend on SFK activity.

open access: yes, 2016
A, Three days after cells were seeded at confluence on 8W10E ECIS electrodes, complete growth media was replaced by EBM-2 containing 0.3% FBS and incubated for another 16 hours. Then, cells were treated with different amounts of TNF-α (as shown). TEER at
Nina Martino (3108468)   +4 more
core   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

open access: yesAdvanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma   +13 more
wiley   +1 more source

No Significant Effect of Daikenchuto (TJ-100) on Peritoneal IL-9 and IFN-γ Levels After Pancreaticoduodenectomy

open access: yesClinical and Experimental Gastroenterology, 2020
Hiromichi Maeda,1,* Ken-ichi Okada,2,* Tsutomu Fujii,3 Mari S Oba,4 Manabu Kawai,2 Seiko Hirono,2 Yasuhiro Kodera,5 Masayuki Sho,6 Takahiro Akahori,6 Yasuhiro Shimizu,7 Yoshiyasu Ambo,8 Naru Kondo,9 Yoshiaki Murakami,9 Jiro Ohuchida,10 Hidetoshi Eguchi ...
Maeda H   +17 more
doaj  

TNF-α and its receptors modulate complex behaviours and neurotrophins in transgenic mice

open access: yes, 2013
Tumour necrosis factor-α (TNF-α) plays an important role not only in immunity but also in the normal functioning of the central nervous system (CNS). At physiological levels, studies have shown TNF-α is essential to maintain synaptic scaling and thus ...
Jaehne, EJ (15579986)   +6 more
core  

TNF-α KO mice do not show microglial deramification or tinnitus after noise exposure.

open access: yes, 2019
A. Example images of microglia stained with IBA1 antibody in TNF-α KO mice with (Noise_5d, 5 days after noise exposure) or without noise exposure (Control). Inserts show enlarged images of microglial morphology. B.
Hao Luo (454719)   +12 more
core   +1 more source

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu   +10 more
wiley   +1 more source

TNF-α activates autophagy in A7r5 cells through an-IKKα dependent pathway.

open access: yes, 2018
(A) Western blot analysis of Beclin1, p62, LC3-II and GAPDH in A7r5 cells stimulated with 0, 1, 10 and 100 ng/mL of TNF-α (n = 4; *pB) Western blot analysis of Beclin1, p62, LC3-II and GAPDH in A7r5 cells incubated with TNF-α (100 ng/mL) at 0, 3, 16, 24 ...
Nicole Cancino-Arenas (5210993)   +9 more
core   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren   +5 more
wiley   +1 more source

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