Results 171 to 180 of about 12,194 (224)
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Anti-trinitrophenyl (TNP) antibody detection by neutralization of TNP-coliphage T4
Immunochemistry, 1969Abstract Anti-trinitrophenyl antibodies are detected by the specific neutralization of bacteriophage T4 haptenated with the picryl radical (TNP). TNP-phage neutralization by anti-TNP is compared to neutralization by anti-phage. Anti-TNP neutralized haptenated phage by two separable first order processes.
P, Barber, M B, Rittenberg
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TNP-LPS induces an IgG anti-TNP immune response in mice
Cellular Immunology, 1979Abstract The trinitrophenylated derivatives of lipopolysaccharide (TNP-LPS) elicit a specific anti-TNP, thymus-independent immune response in mice. After a single injection of antigen, anti-TNP antibodies of IgM and IgG isotypes are detected at the cellular and at the humoral levels, in athymic nude mice as well as in conventional (C57B1/6 × DBA/2)F ...
Humbert, J, Motta, I, Truffa, bachi P
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Journal of Immunological Methods, 1976
Peroxidase (PO), alkaline phosphatase, and glucose oxidase, as well as Fab anti-PO, were coupled with varying molar ratios of trinitrophenyl (TNP) hapten. These reagents were evaluated for their ability to detect anti-TNP antibodies in the lymph node cells of Balb/c mice immunized with heavily-substituted TNP45 alkaline phosphate, which gave rise only ...
D E, Stage, S, Avrameas
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Peroxidase (PO), alkaline phosphatase, and glucose oxidase, as well as Fab anti-PO, were coupled with varying molar ratios of trinitrophenyl (TNP) hapten. These reagents were evaluated for their ability to detect anti-TNP antibodies in the lymph node cells of Balb/c mice immunized with heavily-substituted TNP45 alkaline phosphate, which gave rise only ...
D E, Stage, S, Avrameas
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Analytica Chimica Acta, 2017 Schiff base organic compound (SOC) has been prepared as a tritopic chemosensor for selective sensing by fluorescence signalling towards ions like Al3+, F− and explosive molecule like TNP. In general, fluorescence like photophysical property has been used
Pritam Ghosh, Priyabrata Banerjee
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The Journal of Immunology, 1975
Abstract The trinitrophenyl hapten (TNP) has been covalently conjugated to bacterial lipopolysaccharides (LPS) to give TNP-LPS. The site of attachment has been suggested to be in the core polysaccharide and lipid A region of the molecule and approximately 2.4 hapten molecules are bound per monomer LPS molecule.
Jacobs, D M, Morrison, D C
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Abstract The trinitrophenyl hapten (TNP) has been covalently conjugated to bacterial lipopolysaccharides (LPS) to give TNP-LPS. The site of attachment has been suggested to be in the core polysaccharide and lipid A region of the molecule and approximately 2.4 hapten molecules are bound per monomer LPS molecule.
Jacobs, D M, Morrison, D C
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2,4,6‐Trinitrophenyl (TNP) responsiveness of anti‐TNP (Sp6) transgenic mice
European Journal of Immunology, 1991AbstractTransgenic mouse models have demonstrated clonal deletion as well as clonal anergy of monospecific, high‐avidity autoreactive B cell. The function and fate of naturally activated B cells, many of them displaying degenerate specificity including autoreactivity, are still a matter of debate. The question was pursued in Sp6‐transgenic mice. Sp6, a
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The Journal of Immunology, 1983
Abstract Injection of trinitrophenyl (TNP)-modified splenocytes (TNP-Sp) into the anterior chamber of the eye results in systemic tolerance to TNP, a phenomenon termed anterior chamber associated immune deviation (TNP-ACAID). Two distinct suppressor pathways develop after the induction of TNP-ACAID.
J C, Waldrep, H J, Kaplan
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Abstract Injection of trinitrophenyl (TNP)-modified splenocytes (TNP-Sp) into the anterior chamber of the eye results in systemic tolerance to TNP, a phenomenon termed anterior chamber associated immune deviation (TNP-ACAID). Two distinct suppressor pathways develop after the induction of TNP-ACAID.
J C, Waldrep, H J, Kaplan
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Nature, 1981
Immunological enhancement—the prolonged survival of tumour or organ allografts brought about by passive immunization of the host with alloantibody directed against the graft's antigens—has not yet been applied successfully to clinical organ transplantation.
I V, Hutchinson, L, Brent
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Immunological enhancement—the prolonged survival of tumour or organ allografts brought about by passive immunization of the host with alloantibody directed against the graft's antigens—has not yet been applied successfully to clinical organ transplantation.
I V, Hutchinson, L, Brent
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TNP-470 inhibits intraabdominal adhesion formation
Journal of Pediatric Surgery, 2000Angiogenesis plays an integral role in wound healing and tissue remodeling. The authors hypothesized that inhibition of angiogenesis would reduce intraabdominal adhesion formation.In 98 C57BL6/J mice, a 2-cm midline laparotomy was performed and a 5 mm2 SILASTIC (Dow Corning, Midland, MI) patch fixed to the right side of the peritoneum.
S C, Chiang +4 more
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The Pharmacokinetics of TNP‐470, a New Angiogenesis Inhibitor
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1997Study Objective . To characterize the pharmacokinetic profile of TNP‐470, a synthetic analog of fumagillin that is a potent inhibitor of angiogenesis and inhibits neovascularization in several solid tumor models. Design .
W D, Figg +6 more
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