Results 91 to 100 of about 45,960 (145)

Neuromuscular activity of bothrops fonsecai snake venom in vertebrate preparations [PDF]

, 2015
CAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORCNPQ – CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOThe neuromuscular activity of venom from Bothrops fonsecai, a lancehead endemic to southeastern Brazil, was ...
Hyslop, Stephen, Collaço, Rita C. O., Barbosa, Ana M., Cogo, José C., Fernandes, Carla T., Toledo, Edvana O., Giaretta, Vânia M.A., Silva, Igor R. F. da, Prudêncio, Luiz S., Rodrigues-Simioni, Léa   +9 more
core  

Comprehensive Analysis of Bufadienolide and Protein Profiles of Gland Secretions from Medicinal Bufo Species

Toxins
Toad Venom (TV) is the dried product of toxic secretions from Bufo bufo gargarizans Cantor (BgC) or B. melanostictus Schneider (BmS). Given the increasing medical demand and the severe depletion of wild toads, a number of counterfeit TVs appeared on the ...
Yunge Fang, Liangmian Chen, Pengfei Wang, Yating Liu, Yuxiu Wang, Zhimin Wang, Yue Ma, Huimin Gao   +7 more
doaj   +1 more source

Rapid structural identification of cytotoxic bufadienolide sulfates in toad venom from Bufo melanosticus by LC-DAD-MS(n) and LC-SPE-NMR.

, 2010
Toad venom, namely, "Chansu" in China, has been widely used for the treatment of heart failure, sores, pains, and various cancers. Upon LC-MS analysis of the venom from Bufo melanosticus collected in Indonesia, new bufadienolide sulfates were identified.
Stuppner, Hermann, Kiss, Robert, Moreno Y Banuls, Laetitia, Gao, Huimin, Schneider, Peter, Kopp, Brigitte, Kaehlig, Hanspeter, Zehl, Martin   +7 more
core   +1 more source

Rapid Structural Identification of Cytotoxic Bufadienolide Sulfates in Toad Venom from Bufo melanosticus by LC-DAD-MSⁿ and LC-SPE-NMR

, 2016
Toad venom, namely, “Chansu” in China, has been widely used for the treatment of heart failure, sores, pains, and various cancers. Upon LC-MS analysis of the venom from Bufo melanosticus collected in Indonesia, new bufadienolide sulfates were identified.
Hermann Stuppner (388594), Peter Schneider (2265), Hanspeter Kaehlig (420581), Huimin Gao (1713544), Brigitte Kopp (1278417), Martin Zehl (420582), Laetitia Moreno Y. Banuls (1912279), Robert Kiss (1426378)   +7 more
core   +1 more source

Bufalin targets E2F2 to transcriptionally inhibit LINC01410 and suppress Wnt/β-catenin signaling in esophageal squamous cell carcinoma

npj Precision Oncology
Bufalin, a main active monomer component extracted from the Traditional Chinese Medicine toad venom, exhibits potent anti-tumour activity across diverse malignancies.
Xiaohong Kang, Yufei Ma, Hongke Zhao, Haoling Zhang, Mridul Roy, Mingjuan Liao, Ying Wei, Xingqiao Li, Yueyang Zhou, Huange Xue, Xiaoxia Yan, Wangzheqi Zhang, Yadong Guo, Fei Cao, Tingmin Chang   +14 more
doaj   +1 more source

Biotransformation of maximakinin, a bradykinin-related nonadecapeptide from toad venom, by mammalian kallikrein and salivary proteases

, 2006
Maximakinin is an N-terminally extended bradykinin (DLPKINRKGPRPPGFSPFR) from the venom of a Chinese toad (Bombina maxima) that displays highly selective activity at mammalian arterial smooth muscle receptors.
O'Rourke, M., Chen, Tianbao, Shaw, Christopher, McKenna, J., Hirst, David   +4 more
core   +1 more source

The smooth muscle pharmacology of maximakinin, a receptor-selective, bradykinin-related nonadecapeptide from the venom of the Chinese toad, Bombina maxima.

, 2004
Structural homologues of vertebrate regulatory peptides found in defensive skin secretions of anuran amphibians often display enhanced bioactivity and receptor binding when compared with endogenous mammalian peptide ligands.
Rao, P.F., Chen, Tianbao, Shaw, Christopher, Hirst, David, O’Rourke, M.   +4 more
core   +1 more source

Biodistribution and Lymphatic Tracking of the Main Neurotoxin of Micrurus fulvius Venom by Molecular Imaging

, 2016
The venom of the Eastern coral snake Micrurus fulvius can cause respiratory paralysis in the bitten patient, which is attributable to β-neurotoxins (β-NTx). The aim of this work was to study the biodistribution and lymphatic tracking by molecular imaging
Castillo, Erick, Luis Medina, Dayanira Paniagua, Alejandro Alagón, Romero-Piña, Mario, Luis Alberto Medina, Vergara, Irene, Erick Castillo, Erick Y. Castillo, Itzel Torres-Viquez, Irene Vergara, Leslie Boyer, Medina, Luis, Boyer, Leslie, V, Paniagua, Dayanira, Leslie V. Boyer, Alagón, Alejandro, Mario Romero-Piña, Torres-Viquez, Itzel, Mario E. Romero-Piña   +19 more
core   +1 more source

Conservation genetics of an island toad: Bufo bufo in Jersey [PDF]

, 2007
On Jersey (British Channel Islands), common toads often reproduce in small, urban ponds. This atypical breeding strategy has implications for their persistence and they have declined on the island in recent times.
John W Wilkinson (16063541), Beebee, Trevor J.C., Wilkinson, John W., Richard A Griffiths (16063544), Trevor J C Beebee (16060847), Griffiths, Richard A.   +5 more
core  

Identification of anti-tumor components from toad venom. [PDF]

Oncol Lett, 2017
Gao F, Wang X, Li Z, Zhou A, Tiffany-Castiglioni E, Xie L, Qian Y.   +6 more
europepmc   +1 more source