Results 111 to 120 of about 84,630 (297)

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

Levels of toxins in oral tobacco products in the UK

, 2006
Objective: This study examined the constituents of smokeless tobacco products available in the UK and compared them with products available in India, Sweden, and the USA Methods: Seven UK brands of smokeless tobacco, including a tooth cleaning powder ...
Bedi, R, Islam, S, Alkhatib, MN, McNeill, A, West, R   +4 more
core  

Harm reduction and tobacco smoking [PDF]

, 2014
The main goal of this work was to investigate behavior and attitude of Czech smokers towards e-cigarettes, smokeless tobacco and reduction of number of cigarettes by means of questionnaire inquiry.
Remešová, Renáta
core  

A Virus‐Inducible E3–RLCK–MADS Module Coordinates Suppression of Plant Immunity and Fertility in Rice

Advanced Science, EarlyView.
ABSTRACT Viruses often hijack host developmental programs to promote infection, but the mechanistic links between reproductive regulation and antiviral immunity remain incompletely understood. Here, we identify a virus‐triggered hierarchical degradation cascade that links antiviral immunity and fertility regulation in rice. We show that the rice grassy
Yuansheng Wu, Fengling Wu, Shiting Huang, Denglu Yang, Xin Lei, Xue Zhang, Na Liu, Peng Gan, Chuan Li, Jie Zhang, Ming Wu, Qingxiao Jia, Shanshan Zhao, Jianguo Wu   +13 more
wiley   +1 more source

Emerging challenges in tobacco control – Heated tobacco products, Harm reduction and the Foundation for a Smoke-Free world

Tobacco Prevention and Cessation, 2018
In order to warrant tobacco industry’s profits and overcome a declining cigarette market, tobacco companies have recently launched the novel heated tobacco products (HTPs), claiming a 90-95% reduction in harmfulness.
Sofia Ravara
doaj   +1 more source

Assessment of Swedish snus for tobacco harm reduction: technical appendix [PDF]

, 2007
This technical appendix details the methods used in an assessment of the potential of snus for tobacco harm reduction using simulation ...
Vos, Theo, Bertram,Melanie Y., Gartner, Coral E., Lim, Stephen S., Hall, Wayne D., Wallace, Angela L.   +5 more
core  

DISPARITIES IN GLOBAL TOBACCO HARM REDUCTION

American Journal of Public Health, 2005
In “Origins of the WHO Framework Convention on Tobacco Control,” Roemer et al. present a compelling argument for a unified global approach to tobacco control.1 However, the Framework Convention on Tobacco Control will not benefit nonsignatory countries, which tend to have few or no existing tobacco control measures in place. Indonesia is the only Asian
Jonathan Nadel, Vaughan Rees, Gregory N. Connolly   +2 more
openaire   +2 more sources

NLSS3 Impairs SHM1 Autophagic Degradation to Regulate Leaf Morphology and Salt Tolerance in Rice

Advanced Science, EarlyView.
In rice, NLSS3 binds and shields SHM1 from autophagic degradation to maintain serine homeostasis. The A132P mutation in nlss3 disrupts this, triggering SHM1 loss, metabolic dysfunction, K+ imbalance, and impaired ROS scavenging, which collectively drive narrow leaves and salt sensitivity.
Xiong Liu, Yulu Yang, Zhiqi Hao, Jing Xu, Huibo Zhao, Qiang Zhang, Deyong Ren, Xia Li, Guojun Dong, Lan Shen, Li Zhu, Jiang Hu, Zhenyu Gao, Qing Li, Qian Qian, Guangheng Zhang   +15 more
wiley   +1 more source

Harm reduction associated with heated tobacco products: A systematic review and meta-analysis

Pakistan Journal of Medical Sciences
Objective: We conducted a systematic review and meta-analysis of randomised studies in humans comparing the outcomes of switching to heated tobacco products (HTPs) versus continuing conventional tobacco smoking by burning.
Javed Akram, S. Akram, Nadia Naseem, Sheeraz Shehzad, A. Rana, Verda Ashraf, A. Akram, Usman E. Sheikh, Miland Joshi, Khalid S. Khan   +9 more
semanticscholar   +1 more source

Histone Modification Complex JMJ704‐HDA709 Negatively Regulates Salinity Tolerance in Rice

Advanced Science, EarlyView.
This study reveals that the rice histone demethylase JMJ704 interacts with HDA709―a H3K9ac deacetylase characterized herein―to form a chromatin‐modifying complex. Under salt stress, OsWRKY72 recruits this complex through interaction with JMJ704 to target loci, repressing the expression of oxidative stress and salt‐responsive genes via removal of ...
Jing Wang, Zhengting Chen, Pengxiang Bai, Biao Liu, Lingling Meng, Jian Zhang, Xu Li, Dao‐Xiu Zhou, Xuan Ma, Yu Zhao   +9 more
wiley   +1 more source