Results 51 to 60 of about 53,250,665 (341)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Associations between childbirth, gang exposure and substance use among young women in Cape Town, South Africa

Substance Abuse Treatment, Prevention, and Policy
The prevalence and influence of gangs on adolescents and young adults remain a concern in Western Cape, South Africa—particularly as they have one of the largest gang presence.
Felicia A. Browne, Tara Carney, Bronwyn Myers, Courtney Peasant Bonner, Wendee M. Wechsberg   +4 more
doaj   +1 more source

Prevalence of tobacco use among 15-20 years old college students in Bengaluru city

Journal of Indian Association of Public Health Dentistry, 2015
Introduction: Tobacco use in children and adolescents is reaching pandemic levels. The World Health Organization predicts that India will have the fastest rate of rise in deaths attributable to tobacco in the productive years of adult life, as a ...
Vasudha Sharma, S S Hiremath, Manjunath Puranik, Shweta Somasundara   +3 more
doaj   +1 more source

Tobacco Product Use Among Middle and High School Students — National Youth Tobacco Survey, United States, 2024

MMWR. Morbidity and mortality weekly report
Use of tobacco products in any form is unsafe, and nearly all tobacco product use begins during adolescence. CDC and the Food and Drug Administration (FDA) analyzed data from the 2024 National Youth Tobacco Survey to determine tobacco product use among U.
Ahmed Jamal, E. Park-Lee, Jan Birdsey, Andrenita West, Monica E. Cornelius, Maria R. Cooper, Hannah Cowan, Jia Wang, Michael D. Sawdey, Karen A. Cullen, Livia Navon   +10 more
semanticscholar   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Disparities in Tobacco Smoking by Sex and Employment Status: Results from South Africa’s First Global Adult Tobacco Survey

Social Sciences
Background/Objectives: Tobacco smoking is a cause of premature death and illness globally. This study examined the prevalence and factors associated with tobacco smoking among South African adults according to sex, education, and employment status among ...
Catherine O. Egbe, Portia Nevhungoni, Mukhethwa Londani   +2 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

KNOWLEDGE AND PRACTICES OF TOBACCO USE AND ITS CONTROL AMONG TOBACCO CONSUMERS IN SELECTED AREAS

Indian Journal of Psychiatric Nursing, 2014
Tobacco use is the leading preventable cause of death and more than five million people die globally from the effects of tobacco use every year. Every eight seconds someone, somewhere in the world dies as a result of tobacco use related complications. It
Pramod V Kademani, Sateesh Sindhe, Shireesh S Shindhe, V. Savitha, Nagarajaiah   +4 more
doaj   +1 more source

Global Status of Knowledge, Attitude and Practice on Tobacco Cessation Interventions Among Dental Professionals: A Systematic Review

Tobacco Use Insights, 2022
BACKGROUND With the emergence of the WHO Framework Convention on Tobacco Control, globally the use of tobacco has decreased notably, although, it still requires efforts at individual, organizational, community level to decrease the rate further.
Harsh Priya, Manali Deb Barma, Bharathi M Purohit, Deepali Agarwal, Upendra Singh Bhadauria, Nitesh Tewari, Shalini Gupta, Deepika Mishra, Rahul Morankar, Vijay Prakash Mathur, Ritu Duggal   +10 more
doaj   +1 more source

The GATS Atlas: Global Adult Tobacco Survey [PDF]

, 2015
The Global Adult Tobacco Survey (GATS) Atlas highlights findings from 22 GATS countries in a user-friendly, visual format and incorporates data covering nearly 60 percent of the world's population.

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