Neurobiological Considerations for Tobacco Use Disorder [PDF]
Neurobiological studies of tobacco/nicotine use examining genetic, molecular, functional, and behavioral correlates have improved our understanding of nicotine/tobacco dependence and have informed treatment. Recent work extending previously established findings and reporting novel methodologies and discoveries in preclinical and human studies are ...
Megha Chawla, K. Garrison
semanticscholar +4 more sources
Peripheral Biomarkers Of Tobacco-Use Disorder: A Systematic Review [PDF]
AbstractIntroductionTobacco use disorder (TUD) is a major worldwide healthcare burden resulting in 7 million deaths annually. TUD has few approved cessation aids, all of which are associated a high rate of relapse within one year. Biomarkers of TUD severity, treatment response, and risk of relapse have high potential clinical utility to identify ideal ...
Dwight F. Newton
openalex +3 more sources
Practice Change After Training Psychiatry Residents in Tobacco Use Disorder
The goal of this study was to evaluate treatment practices among psychiatry residents before and 3 months after a course on tobacco use disorder. After completing the course, residents (N=89) reported a significant increase in the frequency in nine of ...
Jill M. Williams+6 more
openalex +2 more sources
Functional Neurocircuits and Neuroimaging Biomarkers of Tobacco Use Disorder. [PDF]
Drug abuse and addiction remain major public health issues, exemplified by the opioid epidemic currently devastating the United States. Treatment outcomes across substance use disorders remain unacceptably poor, wherein drug discovery/development for this multifaceted neuropsychiatric disorder focuses on single molecular-level targets.
M. Sutherland, E. Stein
semanticscholar +4 more sources
Psychedelics as a potential treatment for tobacco use disorder: a systematic review. [PDF]
Despite considerable efforts, tobacco use disorder persists as a significant public health issue. The effectiveness of current smoking cessation therapies is limited, leading to a growing interest in alternative treatment approaches such as psychedelics.The aim of this review is to evaluate the scientific evidence regarding the role of psychedelics in ...
Spoelstra SK+3 more
europepmc +4 more sources
Executive Functions in Tobacco Use Disorder: New Challenges and Opportunities. [PDF]
There is increasing evidence that executive functions have significative effects on nicotine abuse. An unresolved challenge for smoking cessation interventions is the detection of factors associated with nicotine use. In order to understand how cognition is affected by nicotine abuse, this study was designed to determine the relationship between years ...
Martín Ríos R+2 more
europepmc +7 more sources
Persistent Tobacco Use During Pregnancy and the Likelihood of Psychiatric Disorders
Objectives. We examined the association between psychiatric disorders and tobacco use during pregnancy. Methods. Data were derived from a population-based cohort of 744 pregnant African American and White low-income women living in urban and rural areas. The Diagnostic Interview Schedule was used to assess women for 20 different psychiatric disorders.
Louise H. Flick+5 more
openalex +5 more sources
Tobacco use disorder and treatment: new challenges and opportunities
Tobacco use remains a global problem, and options for consumers have increased with the development and marketing of e-cigarettes and other new nicotine and tobacco products, such as “heat-not-burn” tobacco and dissolvable tobacco.
D. Ziedonis, Smita Das, C. Larkin
semanticscholar +6 more sources
SLC6A4 STin2 VNTR genetic polymorphism is associated with tobacco use disorder, but not with successful smoking cessation or smoking characteristics: a case control study. [PDF]
The aim of this study was to determine if variable number of tandem repeats (VNTR) in the second intron (STin2) of the serotonin transporter (SLC6A4) gene was associated with tobacco use disorder, successful smoking cessation, or smoking characteristics.
Ariza, Carolina Batista+11 more
core +3 more sources
Electronic Cigarettes: an Overlooked Tool to Alleviate Disparities in Tobacco Use Disorder Among People with Mental Health and Substance Use Disorders. [PDF]
Vuong JT+3 more
europepmc +3 more sources