Results 191 to 200 of about 100,944 (279)

Tocilizumab as an effective treatment option for idiopathic orbital inflammation: a case report and literature review. [PDF]

Int J Ophthalmol
Zhang HY, Zhang HJ, Zhou HF.
europepmc   +1 more source

Different Immune Cells Modified With Chimeric Antigen Receptors Are Being Applied to Ovarian Cancer: Which Is the Most Effective?

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Ovarian Cancer (OC), the deadliest gynecological malignancy, poses a major therapeutic challenge in advanced stages owing to its high recurrence rate and metastatic potential. In this regard, it is noteworthy that immunotherapy has recently gained significant attention in OC treatment, a phenomenon attributable to notable advances in over‐the ...
Liying Wang, Yisen Cao, Yuan Ren, Yuhang Zhang, Liang Wang   +4 more
wiley   +1 more source

Immunomodulators in Graves' ophthalmopathy: a systematic review. [PDF]

Front Endocrinol (Lausanne)
Yeung A, Siddiqui MS, Mirtorabi N, Ahmed UN, Watts E, Sharma N, Kumari R, Boelaert K, Muzaffar J, Nieto H.   +9 more
europepmc   +1 more source

DEC1 Deficiency Attenuates Breast Cancer‐Induced Osteolytic Destruction by Suppression of Cancer‐Associated Fibroblast Differentiation

Cancer Medicine, Volume 15, Issue 5, May 2026.
Schematic diagram of the mechanism by which DEC1 deficiency attenuates breast cancer‐induced osteolytic destruction through suppression of cancer‐associated fibroblast differentiation. ABSTRACT Background Cancer‐associated fibroblasts (CAFs) in the bone microenvironment play a key role in breast cancer (BC) osteolytic bone metastases.
Zhiyi Qiang, Ying Huo, Lan Lin, Kaiao Chen, Wei Liu, Jian Yang   +5 more
wiley   +1 more source

Giant cell arteritis initially presents as pulmonary embolism. [PDF]

Rheumatol Immunol Res
Xu X, Wang D, Zhu T, Li J.
europepmc   +1 more source

Severe Adult HLH/MAS With SPTCL‐Like Panniculitis: A Phenotype‐Guided, Resource‐Adapted Therapeutic Strategy Without Cytotoxic Therapy

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Graphical abstract illustrating the phenotype‐guided therapeutic approach in severe adult HLH/MAS with SPTCL‐like panniculitis, demonstrating clinical and biochemical response following sequential treatment with therapeutic plasma exchange, intravenous immunoglobulin, and cyclosporine.
Hatem Mousa Taha, Omar Marouf, Khaled Hatem Taha   +2 more
wiley   +1 more source

Tocilizumab combined with short-term high-dose glucocorticoids for rapid disease activity control and glucocorticoid reduction in adult-onset Still's disease: a single-center retrospective study. [PDF]

Front Immunol
Zhong SL, Lei YP, Zhou LX, Niu AX, Liu B, He YL, Yang QB.   +6 more
europepmc   +1 more source

Giant Cell Arteritis With Mesenteric Involvement and Superimposed Functional Gut Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
FDG PET‐CT images of giant cell arteritis with mesenteric involvement. ABSTRACT Giant cell arteritis‐associated mesenteric vasculitis is a rare manifestation and often carries significant mortality and morbidity. We present a case of GCA with mesenteric involvement that was at first diagnostically challenging, contributed to by a history of functional ...
Benjamin Rao, Ronan O'Connor
wiley   +1 more source

Effectiveness and safety of tocilizumab combined with different high-dose methylprednisolone regimens for acute necrotizing encephalopathy in children. [PDF]

Pediatr Investig
Li F, Li K, Fan C, Wang Q, Qian S.
europepmc   +1 more source

Etiopathogenesis of Immune‐Mediated Necrotizing Myopathy: A Comprehensive Review of Recent Advances

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
This review systematically clarifies that the core of IMNM begins with specific autoantibodies, which in turn trigger complement activation, immune cell infiltration, and a storm of inflammatory factors. Together, these processes induce regulatory cell death and mitochondrial dysfunction, ultimately leading to muscle fiber necrosis. Genetic factors and
Chang Gao, Wenli Li, Qingyan Liu, Guochun Wang, Qinglin Peng   +4 more
wiley   +1 more source