Results 141 to 150 of about 62,912 (312)

Concurrent Psoriasis and Dermatomyositis: Retrospective Analysis and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Psoriasis (PsO) and dermatomyositis (DM) are both autoimmune‐mediated, inflammatory conditions. The concurrence of PsO and DM is rare, and literature on their relationship remains limited. Additionally, cutaneous DM can be challenging to clinically diagnosis, often presenting with psoriasiform clinical features.
Emily R. Gordon, Karishma S. Shah, Sidharth Chand, Bonnie Lee, Janellen Smith, Michelle S. Min   +5 more
wiley   +1 more source

Chronic Myeloid Leukemia in a Patient Receiving Tofacitinib: A Case Report and Literature Review

Case Reports in Rheumatology, 2019
Background. Tofacitinib is a new oral Janus kinase inhibitor that has shown promising clinical benefit in various rheumatologic diseases. However, many concerns related to the development of malignancies have been reported with its use. Case Presentation.
Georgio Medawar, Joseph Chahrouri, Rabih Said   +2 more
doaj   +1 more source

Tailored treatment options for patients with psoriatic arthritis and psoriasis: review of established and new biologic and small molecule therapies [PDF]

, 2016
The diverse clinical picture of PsA suggests the need to identify suitable therapies to address the different combinations of clinical manifestations. This review aimed to classify the available biologic agents and new small molecule inhibitors (licensed
Ciurtin, C, Elyoussfi, S, Thomas, BJ
core   +1 more source

Letter: Tofacitinib, vedolizumab and ustekinumab in patients with ulcerative colitis [PDF]

, 2023
Hui‐Chin Chang, Shuo‐Yan Gau
openalex   +1 more source

Assessing the Effect of Adalimumab in Granuloma Annulare: A Case Series and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Granuloma annulare (GA) is a benign granulomatous skin disorder for which standardized treatment guidelines are lacking due to limited evidence. Adalimumab, a TNF‐α inhibitor, shows promise as a therapeutic option due to its potential to disrupt GA granulomas.
Adriana Caixinha Valorenzos, Line Kibsgaard, Trine Bertelsen   +2 more
wiley   +1 more source

Tofacitinib in acute severe ulcerative colitis: review addressing seven key unmet needs

Therapeutic Advances in Gastroenterology
Tofacitinib, an oral Janus kinase (JAK) inhibitor, shows promise as a rescue therapy for acute severe ulcerative colitis (ASUC), a life-threatening condition marked by high colectomy rates.
Chuong Dinh Nguyen, Luan Minh Dang, Thong Duy Vo, Hoang Huu Bui, Eun Soo Kim, Joyce Wing Yan Mak, Choon Jin Ooi   +6 more
doaj   +1 more source

Effectiveness and safety of tofacitinib in rheumatoid arthritis: a cohort study

Arthritis Research & Therapy, 2018
Background Tofacitinib is the first oral Janus kinase inhibitor approved for the treatment of rheumatoid arthritis (RA). We compared the effectiveness and safety of tofacitinib, disease-modifying antirheumatic drugs (DMARDs), tumor necrosis factor ...
Marina Amaral de Ávila Machado, Cristiano Soares de Moura, Steve Ferreira Guerra, Jeffrey R. Curtis, Michal Abrahamowicz, Sasha Bernatsky   +5 more
doaj   +1 more source

Biallelic JAK1 mutations in immunodeficient patient with mycobacterial infection [PDF]

, 2016
Mutations in genes encoding components of the immune system cause primary immunodeficiencies. Here, we study a patient with recurrent atypical mycobacterial infection and early-onset metastatic bladder carcinoma.
Angulo, I, Burns, SO, Curtis, J, Daza-Cajigal, V, Doffinger, R, Eletto, D, Gaspar, M, Gilmour, KC, Henriquez, F, Kumararatne, D, Nejentsev, S, Nowak, K, Plagnol, V, Thrasher, AJ   +13 more
core   +2 more sources

Risk of dyslipidemia and major adverse cardiac events with tofacitinib versus adalimumab in rheumatoid arthritis: a real-world cohort study from 7580 patients

Frontiers in Pharmacology
Objective To compare the effects of tofacitinib and adalimumab on the risk of adverse lipidaemia outcomes in patients with newly diagnosed rheumatoid arthritis (RA). Methods Data of adult patients newly diagnosed with RA who were treated with tofacitinib
Xiao-Na Ma, Mei-Feng Shi, Shiow-Ing Wang, Wei Feng, Shu-Lin Chen, Xiaoqin Zhong, Qingping Liu, James Cheng-Chung Wei, Chang-song Lin, Qiang Xu   +9 more
semanticscholar   +1 more source

Tofacitinib [PDF]

, 2010
Adis Editorial
openalex   +1 more source