Results 171 to 180 of about 53,280 (246)

T Cell Immunosenescence in Inflammatory Skin Diseases: Pathogenesis and Therapeutic Targets

Aging Cell, Volume 25, Issue 5, May 2026.
Immunosenescent T cells promote inflammatory skin diseases such as psoriasis, atopic dermatitis, rosacea, and seborrheic dermatitis via hyperactive signaling networks and SASP secretion. Consequently, intercepting downstream SASP, inhibiting internal pathways, or utilizing senolytics represents promising therapeutic interventions.
Conghui Liu, Ming Yang, Fugang Xiao, Jinrong Zeng   +3 more
wiley   +1 more source

Development and Validation of an HPLC-MS/MS Method for Pharmacokinetic Evaluation of Tofacitinib/Simvastatin Compound Ointment in Rats. [PDF]

Drug Des Devel Ther
Wang S, Zhang C, Li J, Li G, Qi Y.
europepmc   +1 more source

Effect of JAK inhibitors on release of CXCL9, CXCL10 and CXCL11 from human airway epithelial cells [PDF]

, 2015
Barnes, PJ, Donnelly, LE, Fenwick, PS, Macedo, P   +3 more
core   +1 more source

Atypical Prurigo Pigmentosa Following Ketogenic Diet: Successful Treatment with Doxycycline and Tofacitinib. [PDF]

Acta Derm Venereol
Zhang X, Bu Z.
europepmc   +1 more source

Advancing IBD Management: A Literature Review on the Role of Non‐Invasive Blood‐Based Biomarkers in Predicting and Assessing Pharmacodynamic Response to Treatment

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Reliable biomarkers that enable noninvasive, longitudinal assessment of disease activity and therapeutic response remain a major unmet need in inflammatory bowel disease (IBD). While colonic biopsies are the gold standard for evaluating mucosal inflammation, their invasive nature and limited spatial and temporal resolution constrain their ...
Mohamed Hassanein, Li Xi, Rathi D. Ryan, Zhan (Harold) Ye, Nessy Tania, Yamato Sano, Joshua Varghese, Diogo Branquinho, Anna Sapone   +8 more
wiley   +1 more source

Tofacitinib for the Management of Refractory Eosinophilic Pustular Folliculitis: A Case Report and Literature Review. [PDF]

Clin Cosmet Investig Dermatol
Zhu D, Lin Y, Li Y, Yao L.
europepmc   +1 more source

Updated review of Janus kinase inhibitors for the management of inflammatory bowel disease. [PDF]

World J Gastrointest Pharmacol Ther
Malakar S, Giri S, Jena A, Nath P.
europepmc   +1 more source

Efficacy and Safety of Extracorporeal Shock Wave Therapy and 1064 nm Nd:YAG Laser in Managing Nodules and Edema Following Cosmetic Injections: A Case Series and Systematic Literature Review

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background Advances in injectable techniques and materials have driven rapid growth in the esthetic injection market, with more products showing excellent efficacy and safety. Nevertheless, adverse reactions continue to be reported, among which chronic inflammatory nodules and swelling are particularly challenging to manage.
Jieyi Wang, Jiaxu Gu, Zhuoying Wang, Peishi Yin, Xingling Jian, Bo Yu   +5 more
wiley   +1 more source

[Real-world evidence on the use of generic tofacitinib in patients with rheumatoid arthritis] [PDF]

Rev Fac Cien Med Univ Nac Cordoba
Di Giuseppe LA, Burgos MA, Posadas Martínez ML, Vargas Casalles AL, Alvarez KE, Buela G, Puga MC, Soriano Guppy ER, Rosa JE.   +8 more
europepmc   +1 more source

VKH-Like Syndrome in a Patient on Tofacitinib. [PDF]

J Vitreoretin Dis
Tran JH, Hosseini H, Tsui E, Au A.
europepmc   +1 more source