Advanced Science, Volume 13, Issue 7, 3 February 2026.This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang +15 more
wiley +1 more source
Efficacy and safety of tofacitinib dose de‐escalation and dose escalation for patients with ulcerative colitis: results from OCTAVE Open [PDF]
, 2019 Bruce E. Sands +16 more
openalex +1 more source
Clinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.ABSTRACT Objectives Chronic kidney disease (CKD) is relatively common in patients with rheumatoid arthritis (RA). Periodontitis and periodontopathic Porphyromonas gingivalis are risk factors for CKD. However, the association of serum immunity to P. gingivalis and its peptidylarginine deiminase (PPAD), as well as periodontitis severity, with CKD in ...
Tetsuo Kobayashi +5 more
wiley +1 more source
Ruxolitinib Suppresses Interferon‐γ‐Induced JAK/STAT Activation in Oral Keratinocytes
Clinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.ABSTRACT Objectives The Janus kinase (JAK)/Signal Transducer and Activator of Transcription (STAT) pathway plays a crucial role in oral inflammatory diseases such as oral lichen planus (OLP) and periodontitis. Interferon‐gamma (IFN‐γ) is a cytokine that activates the JAK/STAT pathway.
Kim N. Stolte +4 more
wiley +1 more source
AB0072 BIOMARKER CHANGES FOR PATIENTS WITH RHEUMATOID ARTHRITIS RECEIVING TOFACITINIB WITH METHOTREXATE OR GLUCOCORTICOIDS VS TOFACITINIB MONOTHERAPY [PDF]
, 2019 Julie Lee +7 more
openalex +1 more source
Outcomes of Tofacitinib Dose Reduction in Patients with Ulcerative Colitis in Stable Remission from the Randomised RIVETING Trial [PDF]
, 2020 Séverine Vermeire +11 more
openalex +1 more source
MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Tofacitinib restores the inhibition of reverse cholesterol transport induced by inflammation: understanding the lipid paradox associated with rheumatoid arthritis [PDF]
, 2017 Sandra Pérez-Baos +6 more
openalex +1 more source
Registry-based observational study of patients with rheumatoid arthritis treated with baricitinib or tofacitinib in a tertiary hospital [PDF]
, 2023 Elena Guillén Benítez +8 more
openalex +1 more source
Novel treatment approaches for keloids and hypertrophic scars in skin of colour
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Andy D. Lee +7 more
wiley +1 more source