Results 31 to 40 of about 1,376 (142)

Inhibition of sodium‐glucose cotransporter 2 ameliorates renal injury in a novel medaka model of nonalcoholic steatohepatitis‐related kidney disease

FEBS Open Bio, Volume 9, Issue 12, Page 2016-2024, December 2019., 2019
Here, we demonstrate that the highly specific sodium‐glucose cotransporter 2 inhibitor (SGLT2I) prevented the progression of nonalcoholic steatohepatitis (NASH)‐related renal injury in a medaka fish model of NASH‐related kidney disease. SGLT2I ameliorates oxidative stress and macrophage accumulation and maintained mitochondrial function in renal ...
Takuro Nagoya, Kenya Kamimura, Ryo Goto, Yoko Shinagawa‐Kobayashi, Yusuke Niwa, Atsushi Kimura, Norihiro Sakai, Masayoshi Ko, Hiroshi Nishina, Shuji Terai   +9 more
wiley   +1 more source

Hyperuricemia in patients with chronic kidney disease: When and what to treat?

Nefrología (English Edition)
Hyperuricemia is frequently associated with gout, renal disease, arterial hypertension and high cardiovascular disease. All CKD patients with a first episode of gout should be treated with hypouricemic drugs to achieve baseline UA levels of less than 6 ...
Marian Goicoechea, Rodrigo García-Marina   +1 more
doaj   +1 more source

The fourth order flux observer with in‐loop filter for permanent magnet synchronous motor sensorless control

IET Electric Power Applications, Volume 18, Issue 11, Page 1421-1434, November 2024.
To enhance the performance of the flux observer in mitigating DC bias and high‐order harmonics, this study introduces a fourth‐ordered flux observer (FOIFFO). Theoretical analysis demonstrates that the FOIFFO exhibits robust attenuation capabilities towards DC bias and harmonics, thereby preventing motor parameter mismatch and additional interference ...
Ziwen Wang, Ciyong Luo, Xiaoshu Jia, Zihao Xing   +3 more
wiley   +1 more source

Renal effects of a sodium‐glucose cotransporter 2 inhibitor, tofogliflozin, in relation to sodium intake and glycaemic status

Diabetes, Obesity and Metabolism, Volume 21, Issue 7, Page 1715-1724, July 2019., 2019
Abstract Aims Little is known about whether sodium intake is associated with the clinical effects of SGLT2 inhibitors (SGLT2is); however, SGLT2is may increase urinary sodium excretion. Thus, we investigated the impact of daily sodium intake on the estimated glomerular filtration rate (eGFR) via an SGLT2i, tofogliflozin (TOFO), in patients with type 2 ...
Kiyohide Nunoi, Yuichi Sato, Kohei Kaku, Akihiro Yoshida, Hideki Suganami   +4 more
wiley   +1 more source

Load restoration of electricity distribution systems using a novel two‐stage method

The Journal of Engineering, Volume 2024, Issue 8, August 2024.
‐A two‐stage algorithm to achieve optimal, accurate, and applicable solutions for SR in distribution networks. ‐Many important considerations include the time of occurrence of the failure and the daily load curve of the network, the position of the maintenance team, the load transfer capability as well as the traffic conditions.
Qasem Asadi, Hamid Falaghi, Maryam Ramezani   +2 more
wiley   +1 more source

Monoartritis gotosa de muñeca asociada a necrosis del semilunar: a propósito de un caso clínico [PDF]

, 1994
Se presenta un caso de monoartritis de muñeca asociada a imágenes radiológicas de necrosis avascular del semilunar que, tras biopsia de la sinovial, se diagnostica de artritis gotosa. Esta asociación es rara. La alteración metabólica que se produce en la
Mackenney Carrasco, Enrique, Olmedo García, N.   +1 more
core  

Testing for concordance between predicted species richness, past prioritization, and marine protected area designations in the western Indian Ocean

Conservation Biology, Volume 38, Issue 4, August 2024.
Abstract Scientific advances in environmental data coverage and machine learning algorithms have improved the ability to make large‐scale predictions where data are missing. These advances allowed us to develop a spatially resolved proxy for predicting numbers of tropical nearshore marine taxa.
Tim R. McClanahan, Alan M. Friedlander, Julien Wickel, Nicholas A. J. Graham, J. Henrich Bruggemann, Mireille M. M. Guillaume, P. Chabanet, Sean Porter, Michael H. Schleyer, M. Kodia Azali, N. A. Muthiga   +10 more
wiley   +1 more source

Reductions in liver enzymes are associated with anti‐hyperglycaemic and anti‐obesity effects of tofogliflozin in people with type 2 diabetes: Post‐hoc analyses

Endocrinology, Diabetes &Metabolism, Volume 7, Issue 1, January 2024.
Reductions in GGT and ALT were associated with the anti‐hyperglycaemic and anti‐obesity effects of tofogliflozin, respectively, in people with T2D. Therefore, GGT and ALT may be surrogate markers for hyperglycaemia and obesity in T2D. Abstract Aims How the pathology of type 2 diabetes (T2D), including hyperglycaemia and obesity, affects liver enzymes ...
Toshinari Takamura, Kohei Kaku, Akihiro Yoshida, Hiromi Kusakabe, Hiroyuki Nakamura, Hideki Suganami   +5 more
wiley   +1 more source

Hiperuricemia en pacientes con enfermedad renal crónica: ¿cuándo y con qué tratar?

Nefrología
Resumen: La hiperuricemia se asocia frecuentemente con gota, enfermedad renal, hipertensión arterial y enfermedad cardiovascular. Todos los pacientes con enfermedad renal crónica que presentan un primer episodio de gota deben ser tratados con fármacos ...
Marian Goicoechea, Rodrigo García-Marina   +1 more
doaj   +1 more source

O turismo na praia do Tofo

Revista da ANPEGE
Praia do Tofo na cidade de Inhambane constitui uma das riquezas turísticas de Moçambique e possui um elevado investimento estrangeiro que altera a produção social do espaço. Nesse sentido, constituía objetivo desta pesquisa identificar como ocorre a articulação do turismo com os circuitos espaciais de produção locais.
Alberto José Mate, Francisco Fransualdo de Azevedo   +1 more
openaire   +1 more source