Results 41 to 50 of about 10,826 (204)

Antivirals Targeting Coronavirus RNA‐Dependent RNA Polymerase and Main Protease: From Mechanisms of Action to Outcomes in COVID‐19 Clinical Trials

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
The target sites of COVID‐19 antivirals discussed in the present opinion paper, namely the RNA dependent RNA polymerase Nsp12 and of the main viral protease Nsp5, are indicated by a red star in the overview of the replication cycle of coronavirus SARS‐CoV‐2.
Harald Brüssow
wiley   +1 more source

The CD147 Protein Complex Is Involved in Entry of Chikungunya Virus and Related Alphaviruses in Human Cells

Frontiers in Microbiology, 2021
Chikungunya virus (CHIKV) is an arbovirus with a global spread and significant public health impact. It is a positive stranded RNA alphavirus belonging to the Togaviridae family.
Lien De Caluwé, Sandra Coppens, Katleen Vereecken, Simon Daled, Simon Daled, Maarten Dhaenens, Maarten Dhaenens, Xaveer Van Ostade, Dieter Deforce, Dieter Deforce, Kevin K. Ariën, Kevin K. Ariën, Koen Bartholomeeusen   +12 more
doaj   +1 more source

Unveiling the Molecular Profile and Antiviral Potential of Costus arabicus L. Against Zika Virus

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
Analysis of the chemical profile and antiviral potential of Costus arabicus L. extracts. ABSTRACT Widely used in Brazilian folk medicine, Costus arabicus L. (Canarana) is a herbaceous plant with promising pharmacological potential. Here, we profile the molecular composition of extracts from different plant organs and evaluate their in vitro activity ...
Alice Rhelly V. Carvalho, José Diogo E. Reis, Ariane Coelho Ferraz, Marília Bueno da Silva Menegatto, Juliana da C. Lopes, Sônia das G. S. R. Pamplona, Milton N. da Silva, Cintia Lopes de Brito Magalhães, Paulo Wender P. Gomes, Consuelo Yumiko Yoshioka e Silva   +9 more
wiley   +1 more source

Response to Chikungunya fever in China: are we ready?

Decoding Infection and Transmission
Chikungunya fever (CHIK) is caused by the Chikungunya virus (CHIKV), a mosquito-borne RNA virus of the Alphavirus genus (family Togaviridae). CHIK has been imported and caused several local epidemic in China in recent years.
Xiaohong Zhou, Xiang Guo, Xiaoguang Chen
doaj   +1 more source

Chikungunya: Una luz en el horizonte

Revista Paraguaya de Reumatología, 2023
La fiebre chikungunya es una enfermedad vírica transmitida a los humanos por mosquitos Aedes ae- gypti y Aedes albopictus, cuyo agente etiológico es el virus chikungunya, un virus de ARN del género de los alfavirus, familia Togaviridae.
Soraya Araya
doaj  

Sindbis virus ts103 has a mutation in glycoprotein E2 that leads to defective assembly of virions [PDF]

, 1989
Sindbis virus mutant ts103 is aberrant in the assembly of virus particles. During virus budding, proper nucleocapsid-glycoprotein interactions fail to occur such that particles containing many nucleocapsids are formed, and the final yield of virus is low.
Hahn, Chang S., Lenches, Edith M., Rice, Charles M., Strauss, Ellen G., Strauss, James H.   +4 more
core  

Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation [PDF]

, 1987
International audienceThe Dark Energy Camera has captured a large set of images as part of Science Verification (SV) for the Dark Energy Survey (DES). The SV footprint covers a large portion of the outer Large Magellanic Cloud (LMC), providing photometry
Abbott, T. M. C., Allam, S. S., Annis, J., Balbinot, Eduardo, Benoit-Levy, A., Bernstein, J. P., Bernstein, R. A., Bertin, E., Brooks, D., Buckley-Geer, E., Cunha, C. E., Da Costa, L. N., DePoy, D. L., Desai, S., Diehl, H. T., Doel, P., Drlica-Wagner, A., Estrada, J., Evrard, A. E., Finley, D. A., Flaugher, B., Frieman, J. A., Girardi, L., Gruen, D., Gruendl, R. A., Honscheid, K., James, D., Kuehn, K., Kuropatkin, N., Lahav, O., Maia, M. A. G., March, M., Marshall, J. L., Miller, C., Miquel, R., Neto, A. Fausti, Ogando, R., Peoples, J., Pieres, A., Plazas, A., Rosell, A. Carnero, Santiago, B. X., Scarpine, V., Schubnell, M., Sevilla-Noarbe, I., Smith, R. C., Soares-Santos, M., Suchyta, E., Swanson, M. E. C., Tarle, G., Tucker, D. L., Walker, A. R., Wechsler, R., Yanny, B., Zuntz, J.   +54 more
core   +4 more sources

Toward Dual‐Function Nanoparticle Platforms for Arboviral Diagnostics and Vaccines: Advances, Challenges, and Future Prospects

Nano Select, Volume 7, Issue 2, February 2026.
This review explores nanoparticle (NP)‐based biosensors and nanovaccine platforms for arboviral infections, highlighting their design, performance, and translational potential. By comparing case studies across viruses, it identifies gold‐standard nanomaterials such as gold NPs (AuNPs), zinc oxide NPs (ZnONPs), molybdenum disulfide (MoS2) nanocomposites,
Peyman Halvaeikhanekahdani, Sajad Zandi, Qadeer Ahmad, Hadiseh Payravand   +3 more
wiley   +1 more source

Site-directed mutagenesis of the proposed catalytic amino acids of the Sindbis virus capsid protein autoprotease [PDF]

, 1990
The structural proteins of Sindbis virus are translated as a polyprotein precursor that is cleaved upon translation. The capsid protein is postulated to be a serine protease that releases itself from the N terminus of the nascent polyprotein by ...
Hahn, Chang S., Strauss, James H.
core  

Advances in dissecting mosquito innate immune responses to arbovirus infection [PDF]

, 2009
Arthropod-borne viruses – arboviruses – are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control ...
A. A. Nash, A. Kohl, Aliyari, Alphey, Barillas-Mury, Barillas-Mury, Best, Blair, Blitvich, Borucki, Bowers, Bowie, Campbell, Campbell, Caudy, Caudy, Christophides, Christophides, Cirimotich, Condreay, Deddouche, Deo, Ding, Dostert, Ferrandon, Fragkoudis, G. Attarzadeh-Yazdi, Galiana-Arnoux, Garcia, Garcia, Garmashova, Geiss, Gillies, Gillies, Girard, GIRARD, Gordon, Gordon, Gould, Halstead, Hedges, Hedges, Hirai, Holt, J. K. Fazakerley, Jiravanichpaisal, Kang, Karpf, Kemp, Kuno, Kyle, Landeg, Lemaitre, Li, Li, Lin, McMeniman, Medeiros, Mims, Molnar, Newton, Obbard, Olson, Osta, Papanayotou, Parikh, Powers, R. Fragkoudis, Randall, Robalino, Robalino, Sabatier, Saleh, Sanchez-Vargas, Sanchez-Vargas, Sanders, Scholthof, Shelly, Sim, Sim, Soldan, Tortosa, Travanty, van Rij, van Rij, Voinnet, Wang, Waterhouse, Weaver, Weaver, Weaver, Weaver, Whitten, Xi, Xie, Yoneyama, Zambon, Zelivianski   +97 more
core   +1 more source