Results 11 to 20 of about 281,327 (265)

Monitoring antimalarial safety and tolerability in clinical trials: a case study from Uganda. [PDF]

, 2008
BACKGROUND: New antimalarial regimens, including artemisinin-based combination therapies (ACTs), have been adopted widely as first-line treatment for uncomplicated malaria.
Njama-Meya Denise, Staedke Sarah G, Catherine Maiteki-Sebuguzi, Sarah G Staedke, Denise Njama-Meya, Moses R Kamya, Kristin Banek, Maiteki-Sebuguzi Catherine, Grant Dorsey, Yeka Adoke, Jagannathan, Prasanna, Dorsey, Grant, Talisuna, Ambrose O, Arthur Mpimbaza, Dorsey Grant, Ambrose O Talisuna, Rosenthal Philip J, Hasifa Bukirwa, Jagannathan Prasanna, Maiteki-Sebuguzi, Catherine, Rosenthal, Philip J, Tamara D Clark, Clark Tamara D, Yeka, Adoke, Banek, Kristin, Nzarubara Bridget, Staedke, Sarah G, Prasanna Jagannathan, Banek Kristin, Mpimbaza Arthur, Bukirwa, Hasifa, Nzarubara, Bridget, Philip J Rosenthal, Njama-Meya, Denise, Clark, Tamara D, Adoke Yeka, Mpimbaza, Arthur, Kamya Moses R, Bridget Nzarubara, Kamya, Moses R, Bukirwa Hasifa, Wabwire-Mangen Fred, Talisuna Ambrose O, Fred Wabwire-Mangen, Wabwire-Mangen, Fred   +44 more
core   +1 more source

Microfluidic oxygen tolerability screening of nanocarriers for triplet fusion photon upconversion [PDF]

, 2021
The full potential of triplet fusion photon upconversion (TF-UC) of providing high-energy photons locally with low-energy excitation is limited in biomedicine and life sciences by its oxygen sensitivity.
Jussi, Isokuortti, Iiro, Kiiski, Timo, Laaksonen, Tiina, Sikanen, Nikita, Durandin   +4 more
core   +1 more source

Safety and tolerability of combination antimalarial therapies for uncomplicated falciparum malaria in Ugandan children. [PDF]

, 2008
BACKGROUND: Combination antimalarial therapy is recommended for the treatment of uncomplicated falciparum malaria in Africa; however, some concerns about the safety and tolerability of new regimens remain.
Njama-Meya Denise, Staedke Sarah G, Catherine Maiteki-Sebuguzi, Denise Njama-Meya, Moses R Kamya, Sarah G Staedke, Maiteki-Sebuguzi Catherine, Grant Dorsey, Yau, Vincent M, Jagannathan, Prasanna, Dorsey, Grant, Talisuna, Ambrose O, Dorsey Grant, Ambrose O Talisuna, Rosenthal Philip J, Jagannathan Prasanna, Maiteki-Sebuguzi, Catherine, Rosenthal, Philip J, Tamara D Clark, Clark Tamara D, Nzarubara Bridget, Staedke, Sarah G, Prasanna Jagannathan, Yau Vincent M, Nzarubara, Bridget, Vincent M Yau, Philip J Rosenthal, Njama-Meya, Denise, Clark, Tamara D, Kamya Moses R, Bridget Nzarubara, Kamya, Moses R, Talisuna Ambrose O   +32 more
core   +1 more source

Delphi consensus recommendation for optimization of pulmonary hypertension therapy focusing on switching from a phosphodiesterase 5 inhibitor to riociguat

Pulmonary Circulation, 2022
Dual combination therapy with a phosphodiesterase‐5 inhibitor (PDE5i) and endothelin receptor antagonist is recommended for most patients with intermediate‐risk pulmonary arterial hypertension (PAH). The RESPITE and REPLACE studies suggest that switching
Franck F. Rahaghi, Vijay P. Balasubramanian, Robert C. Bourge, Charles D. Burger, Murali M. Chakinala, Michael S. Eggert, Jean M. Elwing, Jeremy Feldman, Christopher King, James R. Klinger, Stephen C. Mathai, John Wesley McConnell, Harold I. Palevsky, Ricardo Restrepo‐Jaramillo, Zeenat Safdar, Jeffrey S. Sager, Namita Sood, Roxana Sulica, R. James White, Nicholas S. Hill   +19 more
doaj   +1 more source

Golimumab for Treating Chronic Inflammatory Joint Diseases in the Adult Population: Clinical Efficacy and Tolerability

Вопросы современной педиатрии, 2019
Due to the recent introduction of golimumab into paediatric rheumatology practice, an overview of the clinical studies of this tumour necrosis factor alpha inhibitor, most of which were conducted with adult patients with rheumatic diseases, has been ...
Natal’ya N. Chichasova
doaj   +1 more source

Pharmacokinetic variables of medium molecular weight cross linked chitosan nanoparticles to enhance the bioavailability of 5-fluorouracil and reduce the acute oral toxicity

Drug Delivery, 2021
To prepare glutaraldehyde-based cross-linked medium molecular weight chitosan nanoparticles encapsulated with 5-Fluorouracil (5-FU), to overcome dosing frequency as well as reducing acute oral toxicity and poor bioavailability of the drug.
Aisha Sethi, Mahmood Ahmad, Tayyaba Huma, Waqas Ahmad   +3 more
doaj   +1 more source

Systematic Review on the Safety and Tolerability of Transcranial Direct Current Stimulation in Children and Adolescents

Brain Sciences, 2021
Background: Transcranial direct current stimulation (tDCS) is a safe, tolerable, and acceptable technique in adults. However, there is limited evidence for its safety in youth.
Derrick Matthew Buchanan, Thomas Bogdanowicz, Neha Khanna, Guillaume Lockman-Dufour, Philippe Robaey, Amedeo D’Angiulli   +5 more
doaj   +1 more source

Indices of homeostasis in cattle after treatment with supramolecular complex of fenbendazole

Российский паразитологический журнал, 2019
The purpose of the research: to study the tolerability of supramolecular complex of fenbendazole (SMCF) by cattle. Materials and methods. Research was conducted in Tepelevo from Dalnekonstantinovsky district of the Nizhny Novgorod region on 20 heifers at
A. I. Varlamova, I. A. Arkhipov
doaj   +1 more source

Tolerability to pirfenidone therapy.

, 2020
Tolerability to pirfenidone therapy.
Zuojun Xu (129186), Chuling Fang (2901452), Jian Guo (191157), Hui Huang (4122), Martin Ferianc (8378925)   +4 more
core   +1 more source

Donanemab (LY3002813) dose‐escalation study in Alzheimer's disease

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021
Introduction This study explored the safety and tolerability features of donanemab (LY3002813) in patients with mild cognitive impairment due to Alzheimer's disease (AD) or mild to moderate AD dementia.
Stephen Loucian Lowe, Brian A. Willis, Anne Hawdon, Fanni Natanegara, Laiyi Chua, Joanne Foster, Sergey Shcherbinin, Paul Ardayfio, John R. Sims   +8 more
doaj   +1 more source