Results 21 to 30 of about 281,327 (265)
Although the number of antihyperglycemic agents has expanded significantly, sulfonylureas (in particular gliclazide MR) remain an important option in the treatment algorithms of type 2 diabetes mellitus (DM2).
Natalia Р. Trubitsyna +1 more
doaj +1 more source
Nefazodone in psychotic unipolar and bipolar depression: A retrospective chart analysis and open prospective study on its efficacy and safety versus combined treatment with amitriptyline and haloperidol [PDF]
Although atypical antipsychotics are on the rise, traditional treatment of psychotic (or delusional) depression mostly includes the addition of classical antipsychotics to antidepressants. As there are only few data supporting this approach compared with
Marcuse, Alain +4 more
core +1 more source
Swati Gulati,1 Tracy R Luckhardt1,2 1Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; 2Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USACorrespondence ...
Gulati S, Luckhardt TR
doaj
Rapid Absorption of Naloxone from Eye Drops
Naloxone as emergency treatment for opioid overdosing can be administered via several routes. However, the available administration methods are invasive or may be associated with incomplete or slow naloxone absorption.
Johanna Tuunainen +8 more
doaj +1 more source
BackgroundQL1604 is a humanized immunoglobulin G4 monoclonal antibody against programmed cell death protein 1. This first-in-human, open-label phase I study aimed to investigate the safety and tolerability and to identify the recommended doses of QL1604 ...
Zhiyu Huang +14 more
doaj +1 more source
Real-World Evaluation of the Tolerability to Onabotulinum Toxin A: The RETO Study [PDF]
Onabotulinumtoxin A (onabotA) has shown efficacy in chronic migraine (CM), with good tolerability and a low rate of adverse effects, most of them not severe.
Ángel L. Guerrero +16 more
core +1 more source
Transcranial magnetic stimulation (TMS) is increasingly used in research and clinical practice, therefore, the issues of its safety and tolerability are especially important. Currently, serious adverse reactions (ARs) are extremely rare.
I. S. Bakulin +5 more
doaj +1 more source
Immediate tolerability (safety cohort).
Immediate tolerability (safety cohort).
Golbahar Pahlavan (632905) +26 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

