Results 21 to 30 of about 341,593 (314)

The use of new aceclofenac dosage forms in patients with osteoarthrosis in real-life clinical practice

open access: yesСовременная ревматология, 2014
A new convenient dosage form of aceclofenac (sashet bags) has recently been launched on the Russian market. The powder in a single sashet bag weighs 3 g, which corresponds to 100 mg of the active ingredient per tablet.
Lyudmila Ivanovna Alekseeva   +5 more
doaj   +1 more source

Golimumab for Treating Chronic Inflammatory Joint Diseases in the Adult Population: Clinical Efficacy and Tolerability

open access: yesВопросы современной педиатрии, 2019
Due to the recent introduction of golimumab into paediatric rheumatology practice, an overview of the clinical studies of this tumour necrosis factor alpha inhibitor, most of which were conducted with adult patients with rheumatic diseases, has been ...
Natal’ya N. Chichasova
doaj   +1 more source

Delphi consensus recommendation for optimization of pulmonary hypertension therapy focusing on switching from a phosphodiesterase 5 inhibitor to riociguat

open access: yesPulmonary Circulation, 2022
Dual combination therapy with a phosphodiesterase‐5 inhibitor (PDE5i) and endothelin receptor antagonist is recommended for most patients with intermediate‐risk pulmonary arterial hypertension (PAH). The RESPITE and REPLACE studies suggest that switching
Franck F. Rahaghi   +19 more
doaj   +1 more source

Pharmacokinetic variables of medium molecular weight cross linked chitosan nanoparticles to enhance the bioavailability of 5-fluorouracil and reduce the acute oral toxicity

open access: yesDrug Delivery, 2021
To prepare glutaraldehyde-based cross-linked medium molecular weight chitosan nanoparticles encapsulated with 5-Fluorouracil (5-FU), to overcome dosing frequency as well as reducing acute oral toxicity and poor bioavailability of the drug.
Aisha Sethi   +3 more
doaj   +1 more source

Systematic Review on the Safety and Tolerability of Transcranial Direct Current Stimulation in Children and Adolescents

open access: yesBrain Sciences, 2021
Background: Transcranial direct current stimulation (tDCS) is a safe, tolerable, and acceptable technique in adults. However, there is limited evidence for its safety in youth.
Derrick Matthew Buchanan   +5 more
doaj   +1 more source

Indices of homeostasis in cattle after treatment with supramolecular complex of fenbendazole

open access: yesРоссийский паразитологический журнал, 2019
The purpose of the research: to study the tolerability of supramolecular complex of fenbendazole (SMCF) by cattle. Materials and methods. Research was conducted in Tepelevo from Dalnekonstantinovsky district of the Nizhny Novgorod region on 20 heifers at
A. I. Varlamova, I. A. Arkhipov
doaj   +1 more source

Environmental Tolerance [PDF]

open access: yesThe American Naturalist, 1987
A theory for the expression of a population's response to density-independent gradients of environmental factors is derived for the case of asexuality. It is shown that the environmental tolerance of a genotype is a function of at least four parameters: g$_1$ and V$_{E1}$, the environmental optimum and its developmental variance between individuals ...
Lynch, Michael, Gabriel, Wilfried
openaire   +3 more sources

Donanemab (LY3002813) dose‐escalation study in Alzheimer's disease

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021
Introduction This study explored the safety and tolerability features of donanemab (LY3002813) in patients with mild cognitive impairment due to Alzheimer's disease (AD) or mild to moderate AD dementia.
Stephen Loucian Lowe   +8 more
doaj   +1 more source

Updated Evaluation of the Safety, Efficacy and Tolerability of Pirfenidone in the Treatment of Idiopathic Pulmonary Fibrosis

open access: yesDrug, Healthcare and Patient Safety, 2020
Swati Gulati,1 Tracy R Luckhardt1,2 1Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; 2Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USACorrespondence ...
Gulati S, Luckhardt TR
doaj  

Review of the results of the EASYDia international observational study. The effect of dose titration of diabeton MR on the effectiveness of treatment of type 2 diabetes

open access: yesСахарный диабет, 2019
Although the number of antihyperglycemic agents has expanded significantly, sulfonylureas (in particular gliclazide MR) remain an important option in the treatment algorithms of type 2 diabetes mellitus (DM2).
Natalia Р. Trubitsyna   +1 more
doaj   +1 more source

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