Results 21 to 30 of about 254,354 (315)

Pharmacokinetic variables of medium molecular weight cross linked chitosan nanoparticles to enhance the bioavailability of 5-fluorouracil and reduce the acute oral toxicity

open access: yesDrug Delivery, 2021
To prepare glutaraldehyde-based cross-linked medium molecular weight chitosan nanoparticles encapsulated with 5-Fluorouracil (5-FU), to overcome dosing frequency as well as reducing acute oral toxicity and poor bioavailability of the drug.
Aisha Sethi   +3 more
doaj   +1 more source

Systematic Review on the Safety and Tolerability of Transcranial Direct Current Stimulation in Children and Adolescents

open access: yesBrain Sciences, 2021
Background: Transcranial direct current stimulation (tDCS) is a safe, tolerable, and acceptable technique in adults. However, there is limited evidence for its safety in youth.
Derrick Matthew Buchanan   +5 more
doaj   +1 more source

Indices of homeostasis in cattle after treatment with supramolecular complex of fenbendazole

open access: yesРоссийский паразитологический журнал, 2019
The purpose of the research: to study the tolerability of supramolecular complex of fenbendazole (SMCF) by cattle. Materials and methods. Research was conducted in Tepelevo from Dalnekonstantinovsky district of the Nizhny Novgorod region on 20 heifers at
A. I. Varlamova, I. A. Arkhipov
doaj   +1 more source

Effect of primaquine dose on the risk of recurrence in patients with uncomplicated Plasmodium vivax: a systematic review and individual patient data meta-analysis [PDF]

open access: yes, 2023
Background: Primaquine is used to eliminate Plasmodium vivax hypnozoites, but its optimal dosing regimen remains unclear. We undertook a systematic review and individual patient data meta-analysis to investigate the efficacy and tolerability of different
Lacerda, Marcus VG   +33 more
core   +1 more source

Donanemab (LY3002813) dose‐escalation study in Alzheimer's disease

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021
Introduction This study explored the safety and tolerability features of donanemab (LY3002813) in patients with mild cognitive impairment due to Alzheimer's disease (AD) or mild to moderate AD dementia.
Stephen Loucian Lowe   +8 more
doaj   +1 more source

Extending single tolerances to set tolerances [PDF]

open access: yesDiscrete Applied Mathematics, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Gerold Jäger, Marcel Turkensteen
openaire   +1 more source

Review of the results of the EASYDia international observational study. The effect of dose titration of diabeton MR on the effectiveness of treatment of type 2 diabetes

open access: yesСахарный диабет, 2019
Although the number of antihyperglycemic agents has expanded significantly, sulfonylureas (in particular gliclazide MR) remain an important option in the treatment algorithms of type 2 diabetes mellitus (DM2).
Natalia Р. Trubitsyna   +1 more
doaj   +1 more source

The Immune Tolerance Network: tolerance at the crossroads [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2001
Immune tolerance therapies are designed to reprogramme immune cells in a highly specific fashion in order to eliminate pathogenic responses but preserve normal immune function. A concept that has tantalized immunologists for decades, tolerogenic therapies would replace current lifelong immunosuppressive regimens and their often debilitating side ...
J A, Bluestone, J, Matthews
openaire   +2 more sources

Updated Evaluation of the Safety, Efficacy and Tolerability of Pirfenidone in the Treatment of Idiopathic Pulmonary Fibrosis

open access: yesDrug, Healthcare and Patient Safety, 2020
Swati Gulati,1 Tracy R Luckhardt1,2 1Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; 2Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USACorrespondence ...
Gulati S, Luckhardt TR
doaj  

Rapid Absorption of Naloxone from Eye Drops

open access: yesPharmaceuticals, 2022
Naloxone as emergency treatment for opioid overdosing can be administered via several routes. However, the available administration methods are invasive or may be associated with incomplete or slow naloxone absorption.
Johanna Tuunainen   +8 more
doaj   +1 more source

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