Results 51 to 60 of about 190,847 (266)

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Tolerability and Safety of Miltefosine for the Treatment of Cutaneous Leishmaniasis

Tropical Medicine and Infectious Disease
Miltefosine, an orally administered drug, is an important component of the therapeutic arsenal against visceral and mucosal forms of leishmaniasis. However, data regarding the safety and tolerability of miltefosine treatment for cutaneous leishmaniasis ...
Nadav Astman, Chen Arbel, Oren Katz, Aviv Barzilai, Michal Solomon, Eli Schwartz   +5 more
doaj   +1 more source

Open-Label Extension Study Comparing Latanoprost 0.005% Without vs With Benzalkonium Chloride in Open-Angle Glaucoma or Ocular Hypertension

Clinical Ophthalmology, 2022
Bridgitte Shen Lee,1 Ranjan Malhotra,2 Kenneth Sall,3 Brittany Mitchell,4 James Peace5 1Vision Optique, Houston, TX, USA; 2Ophthalmology Associates, St. Louis, MO, USA; 3Sall Research Medical Center, Inc., Artesia, CA, USA; 4Medical Affairs North America,
Shen Lee B, Malhotra R, Sall K, Mitchell B, Peace J   +4 more
doaj  

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study from the EUSTAR Cohort

Arthritis Care &Research, Accepted Article.
Objective JAK inhibitors (JAKis) have shown promising effects in early‐phase studies of SSc. We aimed to assess the safety and explore effectiveness of JAKis compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the EUSTAR cohort was performed.
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P Denton, Madelon C Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

Рrospective multicenter study of treatment efficacy, safety, and quality of life in a large cohort of patients with inborn errors of immunity receiving subcutaneous immunoglobulin by the rapid push method

Frontiers in Immunology
Subcutaneous immunoglobulin (SCIG) preparations are widely used in patients with inborn errors of immunity (IEI), with proven efficacy and good tolerance.
Asmik Avedova, Elena Deripapa, Yulia Rodina, Anna Mukhina, Elena Latysheva, Daria Yukhacheva, Vasily Burlakov, Nellie Kan, Daria Bogdanova, Anna Moiseeva, Natalia Kuzmenko, Zoya Nesterenko, Ekaterina Deordieva, Anna Ogneva, Victoria Bludova, Anna Roppelt, Daria Fomina, Natalia Zinovieva, Yulia Sevostyanova, Linara Kalmeteva, Dilara Prolygina, Lyudmila Barycheva, Olga Selezneva, Natalya Shakhova, Olga Laba, Elena Vlasova, Alla Gorenkova, Elena Timofeeva, Olga Trusova, Marina Guseva, Natalya Yudina, Evgeniya Grevtseva, Asya Ibisheva, Zema Bambaeva, Dina Mashkovskaya, Svetlana Isakova, Almazia Shakirova, Ekaterina Selina, Tatyana Shilova, Elena Zubova, Iman Khabaeva, Ekaterina Kitova, Anastasia Mandzhieva, Svetlana Starikova, Tatyana Pavlova, Elvira Tyulyakova, Pavel Levin, Nikolay Grachev, Anna Shcherbina   +48 more
doaj   +1 more source

Incorporation of Selenium into Sol–Gel‐Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity

Advanced Engineering Materials, EarlyView.
Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni, Thalita Marcolan Valverde, Talita Martins, Guilherme Mattos Jardim Costa, Alfredo Miranda de Goes, Marcello Rosa Dumont, Eduardo Henrique Martins Nunes, Marivalda de Magalhães Pereira   +7 more
wiley   +1 more source

Results of a meta-analysis comparing the tolerability of lercanidipine and other dihydropyridine calcium channel blockers

Кардиоваскулярная терапия и профилактика, 2010
Background. Results from clinical studies suggest that the dihydropyridine calcium channel blocker (d-CCB) lercanidipine may be associated with a lower incidence of peripheral edema than are older d-CCBs. Aim. To conduct a meta-analysis of published data
K. Makarounas-Kirchmann, S. Glover-Koudounas, P. Ferrari   +2 more
doaj  

Topical probiotic Lactobacillus lactis treatment in atopic dermatitis: a placebo-controlled pilot study on tolerability and efficacy

Frontiers in Medicine
IntroductionMicrobiome-targeted treatments have been investigated in atopic dermatitis (AD). We aimed to investigate the tolerability and efficacy of probiotic Lactobacillus lactis lysate cream in AD.MethodsA total of 13 patients with mild-to-moderate AD
Ville Salo, Anita Remitz, Antti Lauerma, Alexander Salava   +3 more
doaj   +1 more source

Antidepressants in Children and Adolescents: Meta-Review of Efficacy, Tolerability and Suicidality in Acute Treatment

Frontiers in Psychiatry, 2020
Antidepressants are prescribed for the treatment of a number of psychiatric disorders in children and adolescents, however there is still controversy about whether they should be used in this population.
Katharine Boaden, Anneka Tomlinson, Anneka Tomlinson, Samuele Cortese, Samuele Cortese, Samuele Cortese, Samuele Cortese, Andrea Cipriani, Andrea Cipriani   +8 more
doaj   +1 more source

Karl Popper and the Mechanisms of Hydrogen Embrittlement

Advanced Engineering Materials, EarlyView.
Representation of the beginning of loss of ductility rather than embrittlement. Small concentrations of hydrogen in a diffusible form within iron are well‐established to harm the mechanical integrity of steels. There are theories that attempt to explain the pernicious role of hydrogen.
H. K. D. H. Bhadeshia
wiley   +1 more source