Results 51 to 60 of about 10,867,351 (301)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga +3 more
wiley +1 more source
The coevolution of virulence : tolerance in perspective [PDF]
, 2010 Coevolutionary interactions, such as those between host and parasite, predator and prey, or plant and pollinator, evolve subject to the genes of both interactors.
Colegrave, Nick +17 more
core +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim +11 more
wiley +1 more source
Event-B Patterns for Specifying Fault-Tolerance in Multi-Agent Interaction
, 2007 Interaction in a multi-agent system is susceptible to failure. A rigorous development of a multi-agent system must include the specification of fault-tolerance in agent interactions for the agents to be able to continue to function independently ...
Ball, Elisabeth +3 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The aim of this paper is to provide a personal perspective on the suQject of design fault tolerance, and in particular software fault tolerance, as it has developed at Newcastle and elsewhere, and to speculate briefly on how the subject might advance in ...
Randell B
core +5 more sources
Tolerance of Radial-Basis Functions Against Stuck-At-Faults [PDF]
, 2005 Eickhoff R, Rückert U. Tolerance of Radial-Basis Functions Against Stuck-At-Faults. In: Proceedings of the International Conference on Artificial Neural Networks (ICANN). Warsaw, Poland; 2005: 1003-1008.Neural networks are intended to be used in future
Eickhoff, Ralf, Rückert, Ulrich
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Research on Part Tolerances for RV-40E Reducer Based on Virtual Prototype Technology
Applied SciencesThe RV-40E reducer is the representative model of the a typical RV reducer, where transmission accuracy and manufacturing cost are two important optimization indicators, while transmission accuracy depends on both the selection of accuracy levels for ...
Shousong Jin +4 more
doaj +1 more source