Results 51 to 60 of about 513,577 (266)

Research on Part Tolerances for RV-40E Reducer Based on Virtual Prototype Technology

open access: yesApplied Sciences
The RV-40E reducer is the representative model of the a typical RV reducer, where transmission accuracy and manufacturing cost are two important optimization indicators, while transmission accuracy depends on both the selection of accuracy levels for ...
Shousong Jin   +4 more
doaj   +1 more source

Precision Die Design by The Die Expansion Method

open access: yesThe Proceedings of the Nigerian Academy of Science, 2013
A new method for the design of precision dies used in cold forging, extrusion and drawing processes is presented. It is based on die expansion. It attempts to provide a clear-cut theoretical basis for the selection of critical die dimensions for this ...
Akii O. Ibhadode FAS
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A Tolerance Type Screening Method Based on Similarity Evaluation

open access: yesApplied Sciences
In the context of automatic generation methods for tolerance specifications, the current approach entails designers subjectively selecting geometric tolerances suitable for annotation from the tolerance types generated through automatic reasoning.
Guanghao Liu, Meifa Huang, Zhemin Tang
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Multi-objective optimization based on improved non-dominated sorting genetic algorithm II for tolerance allocation of auto-body parts

open access: yesAdvances in Mechanical Engineering, 2017
The auto-body is usually composed of compliant sheet metals. The assembly variation is inevitable in the process of auto-body assembly. A reasonable tolerance allocation method for compliant sheet metal body parts is an important means to control ...
Sha Xu, Yanfeng Xing, Weifeng Chen
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Optimal F-Number of Ritchey–Chrétien Telescope Based on Tolerance Analysis of Mirror Components

open access: yesApplied Sciences, 2020
The Ritchey–Chrétien telescope has been the key optical module for remote sensing instruments (RSI), in which the root mean square (RMS) random surface wavefront error and the alignment error of the primary and the secondary mirror takes the highest ...
Sheng-Feng Lin   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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