Results 141 to 150 of about 11,008 (309)
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Tolerance before Secularism: Models of Tolerance in Nineteenth-Century Arabic
ReligionsBy analyzing temporal language, this study investigates the intellectual origins and the conceptual history of three concepts of tolerance that emerged in the Arabic context towards the end of the 19th century.
Wael Abu-ʿUksa
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Preoperative Immunocyte-Derived Ratios Predict Postoperative Recovery of Gastrointestinal Motility after Colorectal Cancer Surgery. [PDF]
J Clin Med, 2023 Firut A +10 more
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Two stories about toleration [PDF]
In current social conflicts in European societies such as the ones concerning the crucifix in classrooms or the foulard or the burka worn in public, toleration is a concept claimed by all involved. The paper uncovers the historical and conceptual reasons
Rainer Forst
core
Ecclesiology, Ecumenism, Toleration [PDF]
, 2013 This contribution discusses Leibniz’s conception of the Christian church, his life-long ecumenical efforts, and his stance toward religious toleration. Leibniz’s regarded the main Christian denominations as particular churches constituting the only one ...
Antognazza, Maria Rosa
core
The Cultural Heritage of Interculturalism
Nordicum-Mediterraneum, 2015 The article traces the cultural heritage of inter-cultural contexts, which have had profound impact over long time. It takes its departure in antique and culturally complex environments in the eastern Mediterranean.
Martin Peterson
doaj
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Pragmatic Universalism – A Basis of Coexistence of Multiple Diversities
Nordicum-Mediterraneum, 2015 The authors examine the paradigms hitherto employed to understand and regulate relations between minorities and majority: universalism, multiculturalism/differentialism and interculturalism.
Paola de Cuzzani, Kari Hoftun Johnsen
doaj