Results 131 to 140 of about 14,603 (295)

JOHN RAWLS'UN SİYASAL LİBERALİZM'INDE HOŞGÖRÜ KAVRAMININ BOYUTLARI

open access: yesFelsefe Dünyası, 2010
Bu makale, 1993'te yayınlanan "Siyasal Liberalizm" eserine özel olarak atıfta bulunarak, John Rawls'un siyaset felsefesinde hoşgörünün boyutlarını incelemektedir.
Devrim Kabasakal
doaj  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Toleration in Conflict

open access: yesMeridiano 47, 2017
FORST, Rainer; “Toleration in Conflict: Past and Present”; Cambridge University Press, United States of America, New York, 2013; 662 pp.
Thiago Corrêa Malafaia
doaj  

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

State Toleration, Religious Recognition and Equality

open access: yes, 2013
In debates about multiculturalism, it is widely claimed that ‘toleration is not enough’ and that we need to go ‘beyond toleration’ to some form of politics of recognition in order to satisfactorily address contemporary forms of cultural diversity (e.g ...
Lægaard, Sune; id_orcid
core  

"These wasps behave just like those men who...": Irony and Optimism in Baroncelli's writings

open access: yesNordicum-Mediterraneum, 2008
How can you conjugate scepticism and optimism? Irony and solidarity? Flavio Baroncelli spent most of his life, both as a scholar and as a human being, on this hard task, and his writings are there to show the results he achieved.
Fabrizio Veneziano
doaj  

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

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