Results 131 to 140 of about 457 (170)

The Synthesis of Deuterated Tolperisone and Tolperisone Metabolites

, 2007
Jordis, Ulrich, Knesl, Petr, Puterova, Zita   +2 more
core  

Upscaling of gaseous alkanes into large-volume commodity chemicals via photocatalytic acylation.

Cell Rep Phys Sci
Nair AM, Barbeira-Arán S, Malga JM, Fañanás-Mastral M.   +3 more
europepmc   +1 more source

A case report of insulin autoimmune syndrome induced by drugs for colorectal cancer. [PDF]

Medicine (Baltimore)
Wu X, Bao L, Fan G, Wang S.
europepmc   +1 more source

The Deleterious Consequences of a Nonsteroidal Anti-inflammatory Drug in an Eisenmenger Patient. [PDF]

CJC Pediatr Congenit Heart Dis
Grütter S, Haefliger D, Wuerzner G, Yerly P, Bouchardy J, Rutz T.   +5 more
europepmc   +1 more source

A Rare Case of Lumbar Region Diastematomyelia in a 25-year-old Woman With Lower Back Pain. [PDF]

Cureus
Velchev V, Iliev B, Petrov PP, Ilyov I, Penchev P.   +4 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Effects of CYP2D6*10 allele on the pharmacokinetics of tolperisone

Archives of Pharmacal Research, 2022
Tolperisone, a muscle relaxant used for post-stroke spasticity, has been reported to have a very wide interindividual pharmacokinetic variability. It is metabolized mainly by CYP2D6 and, to a lesser extent, by CYP2C19 and CYP1A2. CYP2D6 is a highly polymorphic enzyme, and CYP2D6*wt/*wt, CYP2D6*wt/*10 and CYP2D6*10/*10 genotypes constitute more than 90%
Choon-Gon Jang, Seok-Yong Lee, Chang-Ik Choi   +2 more
exaly   +3 more sources

HPLC Determination of tolperisone in human plasma

Archives of Pharmacal Research, 2006
A simple high performance liquid chromatographic (HPLC) method was developed for the determination of tolperisone in human plasma. Tolperisone and internal standard (chlorphenesin) were isolated from 1 mL of plasma using 8 mL of dichlormethane. The organic phase was collected and evaporated under nitrogen gas.
Jung-Woo Bae, Young-Seo Park, Choon-Gon Jang   +2 more
exaly   +3 more sources

Effects of CYP2C19 genetic polymorphism on the pharmacokinetics of tolperisone in healthy subjects

Archives of Pharmacal Research, 2022
Tolperisone hydrochloride is a centrally-acting muscle relaxant used for relieving spasticities of neurological origin and muscle spasms associated with painful locomotor diseases. It is metabolized to the inactive metabolite mainly by CYP2D6 and, to a lesser extent, by CYP2C19 and CYP1A2.
Choon-Gon Jang, Seok-Yong Lee, Yun Jeong Lee   +2 more
exaly   +3 more sources

NMR analysis, protonation equilibria and decomposition kinetics of tolperisone

Journal of Pharmaceutical and Biomedical Analysis, 2009
The rate constants of spontaneous and hydroxide-catalyzed decomposition and the tautomer-specific protonation constants of tolperisone, a classical muscle relaxant were determined. A solution NMR method without any separation techniques was elaborated to quantitate the progress of decomposition. All the rate and equilibrium constants were determined at
Gabor Orgovan, Karoly Tihanyi, Bela Noszál   +2 more
exaly   +3 more sources