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Tolperisone: Evaluation of the Lidocaine‐Like Activity by Molecular Modeling
Archiv der Pharmazie, 1996AbstractTolperisone (1), a muscle relaxant with lidocaine‐like activity, was compared to lidocaine (2) by molecular modeling methods. Conformational search analysis has been employed to find the global minima of these compounds along with numerous low energy conformations from which specific conformers were extracted that show good superimposition of ...
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[Neuropharmacological studies on tolperisone hydrochloride (author's transl)].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980Neuropharmacological properties of tolperisone hydrochloride (2,4'-dimethyl-3-piperidinopropiophenone hydrochloride) were investigated in mice, rats and cats. Tolperisone inhibited the spontaneous movement and methamphetamine-induced hyperactivity in mice and the ED50 was approx. 50 mg/kg, s.c.
Y, Fujii +3 more
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Rapid removal of tolperisone from waters by application of heterogeneous photocatalysis
2022Tolperisone hydrochloride (TLP) is a piperidine derivative and belongs to the group of muscle relaxant pharmaceuticals. TLP affects spasticity through interaction with upper motor neurons (central acting muscle relaxants). It is commercially available under different trademarks (e.g.
Šojić Merkulov, Daniela +5 more
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Optimal removal of tolperisone from waters by photocatalysis, nanotechnology and chemometrics
2022Environmental pollution with various pharmaceuticals is becoming serious global issue. When various chemicals are released into environmental waters above capacity for their removal they disturb the ecosystems of flora and fauna in both, water and (indirectly) in terrestrial ecosystems.
Putnik, Predrag +5 more
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Drug hypersensitivity to tolperisone – case report
Alergologia, 2019Corina Ureche +3 more
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