Results 21 to 30 of about 457 (170)

Tolperisone in the combination treatment of muscular tonic syndrome in individuals with a high level of physical activity

open access: yesМедицинский совет, 2021
Introduction. Dorsalgia is one of the most common diseases in individuals practising regular physical training and sports Rationale. Because of the growth of the number of physically active individuals expected to rise by 2024, the improvement of drug ...
O. G. Gutianskii, A. N. Zarubin
doaj   +3 more sources

Chemoreactome analysis of tolperisone, tizanidine, and baclofen molecules: anticholinergic, antispasmodic, and analgesic mechanisms of action

open access: yesНеврология, нейропсихиатрия, психосоматика, 2018
Muscle relaxants are used in the treatment of musculoskeletal pain. The exact molecular mechanisms of action of muscle relaxants are not always clear. Some muscle relaxants show mainly an anticholinergic effect, others have GABAergic one; they differ in ...
I. Yu. Torshin   +3 more
doaj   +3 more sources

Screen-printed sensors for efficient potentiometric analysis of tolperisone hydrochloride in presence of its co-formulated drugs [PDF]

open access: yesBMC Chemistry, 2022
Researchers seeking for green chemistry to help safeguard and boost the economy and the environment by discovering unique ways to decrease waste and find substitutes for dangerous chemicals.
Mohamed Rizk   +4 more
doaj   +2 more sources

On the mechanisms of the synergistic action of tolperisone, meloxicam and B vitamins in the treatment of peripheral pain syndromes

open access: yesМедицинский совет, 2020
Introduction: The combined use of non-steroidal anti-inflammatory drugs (NSAIDs), muscle relaxants and group B vitamins is a promising direction for combined pharmacotherapy of peripheral pain syndromes.Purpose: to analyze the molecular mechanisms of the
O. A. Gromova   +4 more
doaj   +3 more sources

The comparative study of clinical efficacy and safety of baclofen vs tolperisone in spasticity caused by spinal cord injury

open access: yesSaudi Pharmaceutical Journal, 2017
In the present study we compared the clinical efficacy and safety of baclofen vs tolperisone in spasticity caused by spinal cord injury. A total of 150 patients were enrolled in the present study and were divided into two groups with 75 patients in each ...
Dejun Luo   +7 more
doaj   +2 more sources

Evaluation of efficacy and safety of combined use of nonsteroidal anti-inflammatory drugs and extended release tolperisone in patients with ankle injuries

open access: yesСовременная ревматология, 2023
Ankle capsular ligamentous apparatus damage is one of the most common problems. Ankle injuries account for one-fifth of all lower extremity sports injuries.
R. I. Sadykov   +3 more
doaj   +3 more sources

Efficacy of tolperisone versus meloxicam in the treatment of nonspecific acute neck pain

open access: yesНеврология, нейропсихиатрия, психосоматика, 2020
Neck pain is a widespread disease that significantly impairs quality of life in patients. General approaches to managing patients with acute neck pain are generally consistent with the recommendations for the treatment of acute back pain: its ...
K. V. Skorobogatykh, Yu. E. Azimova
doaj   +3 more sources

Central muscle relaxants in rheumatology practice

open access: yesСовременная ревматология, 2021
The article describes the general principles of the treatment of musculoskeletal pain, discusses modern approaches to the treatment of osteoarthritis (OA) and nonspecific back pain (NBS).
E. Yu. Polishchuk   +2 more
doaj   +4 more sources

Anaphylactic reactions to tolperisone (Mydocalm®)

open access: yesSwiss Medical Weekly, 2003
Four patients with anaphylaxis attributed to the intake of the centrally acting muscle relaxant tolperisone hydrochloride (Mydocalm) were observed at the Emergency Department of the Geneva University Hospital between November 2001 and March 2003. All patients were middle-aged women who took tolperisone for chronic muscular pain.
C Vermeulen
doaj   +3 more sources

Nonsteroidal anti-inflammatory drugs, muscle relaxants, and B-group vitamins in the treatment of lumbar ischialgia

open access: yesНеврология, нейропсихиатрия, психосоматика, 2020
Nonsteroidal anti-inflammatory drugs (NSAIDs) and muscle relaxants are used orally or intramuscularly (IM) to treat lumbar ischialgia caused by musculoskeletal disorders or radiculopathy. A comparative study has been conducted to investigate the efficacy
V. A. Shirokov   +2 more
doaj   +3 more sources

Home - About - Disclaimer - Privacy