Results 31 to 40 of about 457 (170)

A Simple Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry Method for Measurement of Cortisol Level in Human Saliva

International Journal of Analytical Chemistry, 2019
A simple ultraperformance liquid chromatography-tandem mass spectrometry assay for measurement of cortisol level in human saliva was developed and validated.
Syed N. Alvi, Muhammad M. Hammami
doaj   +2 more sources

Back pain: diagnostic and differential aspects

Неврология, нейропсихиатрия, психосоматика, 2019
Management of patients with back pain is an interdisciplinary problem requiring a package of diagnostic and differential measures. Despite the elaboration of algorithms for the differential diagnosis and therapy of back pain, a number of questions remain
E. G. Mendelevich
doaj   +3 more sources

Myofascial pain syndrome in female patients with chronic nonspecific back pain: diagnosis and treatment

Неврология, нейропсихиатрия, психосоматика, 2020
Objective: to elucidate the frequency and pathogenesis of myofascial pain syndrome (MFPS) in chronic nonspecific lower back pain (CNLBP) and to optimize the diagnosis and treatment of MFPS in CNLBP.Patients and methods.
D. O. Rozhkov, O. E. Zinovyeva, A. N. Barinov, I. M. Vikhlyantsev, G. Z. Mikhailova, N. V. Penkov, A. M. Nosovsky   +6 more
doaj   +3 more sources

Antinociceptive Effects of Sodium Channel-Blocking Agents on Acute Pain in Mice

Journal of Pharmacological Sciences, 2004
The effects of various sodium channel blocking agents on acute thermal and mechanical nociception, as assessed using the plantar and tail pressure tests, respectively, were compared with the effects of morphine. The drugs used were mexiletine, lidocaine,
Akiko Sakaue, Motoko Honda, Mitsuo Tanabe, Hideki Ono   +3 more
doaj   +2 more sources

Untargeted Safety Pharmacology Screen of Blood-Activating and Stasis-Removing Patent Chinese Herbal Medicines Identified Nonherbal Ingredients as a Cause of Organ Damage in Experimental Models [PDF]

Frontiers in Pharmacology, 2019
Blood activation and stasis removal from circulation is a central principle for treatment of syndromes related to cerebral and cardiovascular diseases in Chinese herbal medicine.
Xinyan Liu, Xinyan Liu, Rui Shao, Rui Shao, Xinyue Yang, Xinyue Yang, Guangxu Xiao, Guangxu Xiao, Shuang He, Shuang He, Yuxin Feng, Yuxin Feng, Yan Zhu, Yan Zhu, Yan Zhu   +14 more
doaj   +2 more sources

Deflazacort-induced Acneiform Eruptions

Journal of Pharmacy and Bioallied Sciences, 2017
A 38-year-old male suffering from a low backache since 3 months was diagnosed as a case of L4-L5 disc prolapse after magnetic resonance imaging examination.
Mohammed Shakeel Mohammed Bashir, Mohammad Saleem, Uday Choudhari   +2 more
doaj   +2 more sources

Treatment for poststroke spasticity, the use of mydocalm

Неврология, нейропсихиатрия, психосоматика, 2011
The paper gives the data available in the literature on the treatment of spasticity in poststroke patients. Therapeutic exercises that should be started just on the first days of stroke are noted to play a leading role in the treatment of poststroke ...
V. A. Parfenov
doaj   +3 more sources

Development and validation of a new reverse-phase high-performance liquid chromatography (RP-HPLC) method for the quantifications of tolperisone loaded in liposomes

Results in Chemistry
Tolperisone (TOL) is a muscle relaxant that tends to undergo uncontrollable degradation in the intestinal medium, leading to low oral bioavailability and the generation of genotoxic degradants.
Rawan N. AlKaraki, Rula R. Haddadin, Shahed K. Tarawneh, Marwa A.M. Alimari, Rehan M. Alkasasbeh, Tebat Al-ferdous E. Shamaileh, Mustafa S. Almohtaseb, Malek G. Hajaya   +7 more
doaj   +2 more sources

An assessment of the centrally acting muscle relaxant tolperisone on driving ability and cognitive effects compared to placebo and cyclobenzaprine. [PDF]

J Clin Pharm Ther, 2020
Tolperisone is a centrally acting muscle relaxant under development for the treatment of acute and painful symptoms of muscle spasm. In this study of driving ability and cognitive effects, subjects who received tolperisone experienced no impact on measures of driving, self‐reported sleepiness, or cognition compared to placebo, in contrast to those who ...
Caron J, Kaye R, Wessel T, Halseth A, Kay G.   +4 more
europepmc   +2 more sources

Sustainable and smart multi-analyte HPTLC determination of tolperisone HCl together with three pain killers using smartphone camera as a detector: Comparative study with benchtop densitometry

Talanta Open
The remarkable advancement in smartphone cameras has revolutionized their potential as highly accessible, portable, and manageable detectors in various analytical approaches.
Mohamed Rizk, Emad Ramzy, Safaa Toubar, Amr M. Mahmoud, Marwa I. Helmy   +4 more
doaj   +2 more sources