Results 51 to 60 of about 457 (170)
Structure of Tolperisone Monohydrochloride
Analytical Sciences: X-ray Structure Analysis Online, 2007 The crystal of the racemate of the title compound, C16H23NO·HCl, belongs to space group P21/c with cell dimensions a = 12.476(6), b = 9.109(4), c = 13.759(7)A, and β = 95.13(4)°. The final R value is 0.0567. The dihedral angle between the least-squares planes of the two rings is 57.1(6)°, and the distance between the centers of the two rings is 7.42 A.
TANAKA, Rumiko, HIRAYAMA, Noriaki
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PAINFUL MUSCLE SPASM: DIAGNOSIS AND PATHOGENETIC THERAPY
Медицинский совет, 2017 The article discusses the pathogenesis, diagnosis and treatment of myofascial pain. The analysis of the effectiveness of muscle relaxants in patients with myofascial pain syndrome is provided.
O. V. Vorobyova
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Journal of Applied Chemistry, Volume 2013, Issue 1, 2013., 2013 A rapid, specific, and sensitive reverse phase high performance liquid chromatographic method has been developed and validated for analysis of tolperisone in both bulk and pharmaceutical dosage form. The HPLC method was performed with a reversed phase C18 SunFire column (250 mm × 4.6 mm i.d., 5 mm particle size), detection at 261 nm and a mixture of ...
U. K. Chhalotiya +5 more
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Determination of Tolperisone Enantiomers in Plasma and Their Disposition in Rats.
Chemical and Pharmaceutical Bulletin, 1992 A stereoselective assay for the determination of tolperisone enantiomers in plasma by high performance liquid chromatography was developed. Calibration curves obtained for the enantiomers were linear over plasma concentrations of 0.1-3.0 micrograms/ml with a detection limit of 20 ng/ml.
YOKOYAMA, Teruyoshi +4 more
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Scandinavian Journal of Medicine &Science in Sports, Volume 35, Issue 9, September 2025.ABSTRACT In wheat allergy dependent on augmentation factors (WALDA), allergic reactions occur when wheat ingestion is combined with exercise or rarely other augmentation factors. We analyzed clinical characteristics and disease burden in recreationally active and trained individuals with WALDA diagnosed by oral challenge test. Clinical characteristics,
Valentina Faihs +5 more
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Неврология, нейропсихиатрия, психосоматика, 2020 Objective: to evaluate the clinical efficacy and tolerability of the Russian drug tolperisone (calmyrex) versus tizanidine and baclofen in the therapy of acute nonspecific musculoskeletal pain (NSMSP) in the elderly.Patients and methods.
R. V. Gorenkov +3 more
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Basic aspects of the pharmacodynamics of tolperisone, a widely applicable centrally acting muscle relaxant [PDF]
, 2014 Tolperisone (2-methyl-1-(4-methylphenyl)-3-piperidin-1-ylpropan-1-one hydro-chloride) was introduced in the clinical practice more than forty years ago and is still evaluated as a widely applicable compound in pathologically elevated skeletal muscle tone
Tekes Kornélia
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Journal of the European Academy of Dermatology and Venereology, Volume 38, Issue 9, Page 1791-1798, September 2024.Abstract Background Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare life‐threatening mucocutaneous reactions most often induced by drugs. To date, no large pharmacovigilance study has been conducted in the paediatric population.
Pauline Bataille +6 more
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Tolperisone for the treatment of low back pain
Clinical pharmacology and therapy, 2022 Tolperisone is a centrally acting muscle relaxant that shows analgesic activity and can be used alone or in combination with NSAIDs for the treatment of nonspecific back pain. Compared with other muscle relaxants tolperison has better safety profile and very low sedative activity.
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STABILITY INDICATING UPLC METHOD FOR QUANTIFICATION OF TOLPERISONE HCL AND PARACETAMOL FROM MUSCLE RELAXANT COMBINATION TABLET [PDF]
, 2015 Objective: In the present work, rapid and sensitive isocratic RP-UPLC method was established and comprehensive validation study for the estimation of Tolperisone HCl and Paracetamol was carried out according to international conference on harmonization ...
Patel, Madhavi +2 more
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