Results 71 to 80 of about 2,286 (170)

Identifying Gene Predictors of Chemicals Linked With Breast Cancer: A Machine Learning Analysis of MCF7 Cellular Transcriptomic Screening Data

Environmental and Molecular Mutagenesis, Volume 66, Issue 8, Page 425-441, October 2025.
ABSTRACT Breast cancer is the most prevalent cancer in women and has been linked to exposure to environmental chemicals. However, many chemicals have not been evaluated for relationships with this outcome. In this study, we analyzed RNA sequencing data from human breast cancer‐derived MCF7 cells exposed to hundreds of individual chemicals.
Lauren E. Koval, Richard Judson, Julia E. Rager   +2 more
wiley   +1 more source

Suplatast tosilate alleviates nasal symptoms through the suppression of nuclear factor of activated T-cells-mediated IL-9 gene expression in toluene-2,4-diisocyanate-sensitized rats

Journal of Pharmacological Sciences, 2016
Histamine H1 receptor (H1R) gene is upregulated in patients with pollinosis; its expression level is highly correlated with the nasal symptom severity.
Hiroyuki Mizuguchi, Naoki Orimoto, Takuya Kadota, Takahiro Kominami, Asish K. Das, Akiho Sawada, Misaki Tamada, Kohei Miyagi, Tsubasa Adachi, Mayumi Matsumoto, Tomoya Kosaka, Yoshiaki Kitamura, Noriaki Takeda, Hiroyuki Fukui   +13 more
doaj   +1 more source

Functional Electrolyte Additives: A Pinch of Salt/Solvent to an Electrolyte for High Energy Density Lithium‐Ion and Lithium–Metal Batteries

Small, Volume 21, Issue 34, August 28, 2025.
Electrolytes, often termed as the “blood” of battery play a decisive role in determining their performance metrics. This review thoroughly analyzes the role of functional electrolyte additives improving the performance and safety of Li‐ion/Li–metal batteries involving film formation, overcharge control, wide temperature and voltage operation ...
Chenrayan Senthil, Amutha Subramani, Ram K. Gupta, Zdeněk Sofer   +3 more
wiley   +1 more source

Characterization and Comparative Analysis of 2,4-Toluene Diisocyanate and 1,6-Hexamethylene Diisocyanate Haptenated Human Serum Albumin and Hemoglobin

, 2016
Diisocyanates (dNCOs) are lowmolecularweight chemical sensitizers that reactwith autologous proteins to produce neoantigens. dNCO-haptenated proteins have been used as immunogens for generation of dNCO-specific antibodies and as antigens to screen for ...
Bledsoe, Toni A., Law, Brandon F., Mhike, Morgen, Beezhold, Donald H., Lemons, Angela R., Green, Brett J., Chipinda, Ita, Simoyi, Reuben H., Nayak, Ajay P., Siegel, Paul D.   +9 more
core   +1 more source

Airway Inflammation and Bronchial Remodelling in Toluene Diisocyanate-exposed BALB/c Mouse Model [PDF]

, 2007
Toluene diisocyanate (TDI), a highly reactive industrial chemical, is one of the leading causes of occupation-related asthma in industrialized countries.
Aasen, T. B., Elsayed, S., Bronstad, A. M., Van Do, T., Irgens, Ågot, Aardal, N. P., Sun, Li-Zhi   +6 more
core   +1 more source

A biodegradable copolymer from coupling poly(pdioxanone) with poly(ethylene succinate) via toluene-2,4- diisocyanate

e-Polymers, 2009
AbstractPoly(p-dioxanone) (PPDO) and poly(ethylene succinate) (PES) prepolymers were reacted together using toluene-2,4-diisocyanate (TDI) as a chain extender to produce high molecular weight of chain-extended products of PPDO and PES (PPDOES) in a suitable reaction condition.
Xiu-Li Wang, Si-Chong Chen, Yu-Hua Zhang, Ke-Ke Yang, Yu-Zhong Wang   +4 more
openaire   +1 more source

TOLUENE DIISOCYANATE-STIMULATED RELEASE OF ARACHIDONIC-ACID METABOLITES IN THE ORGAN BATH FROM GUINEA-PIG AIRWAYS

, 1993
This study was designed to evaluate whether metabolites of arachidonic acid play a role in the contractile response to toluene diisocyanate in isolated guinea pig airways. In control experiments we collected the supernatant from an organ bath over a time
BONIOTTI A, Saetta M, MASIERO M, CIACCIA A, Maestrelli P, BURLINA A, MAESTRELLI, PIERO, SAETTA, MARINA, PLEBANI M, PAPI, Alberto, FABBRI L., FABBRI, Leonardo, PAPI A, MAPP CE   +13 more
core   +1 more source

Chemical analysis of 2,4-toluene diisocyanate, 1,6-hexamethylene diisocyanate and isophorone diisocyanate in petrolatum patch-test preparations.

, 2005
Background: Isocyanates with the general formula R-(N=C=O) are theoretically contact sensitizers. However, allergic contact dermatitis (ACD) from isocyanates is seldom reported.
Karlsson, Daniel, Isaksson, Marléne, Zimerson, Erik, Skarping, Gunnar, Engfeldt, Malin, Bruze, Magnus, Marand, Åsa   +6 more
core  

Intestinal obstruction in acute inhalational toluene 2,4-diisocyanate gas toxicity.

The international journal of occupational and environmental medicine, 2013
The isocyanates are widely used as precursors of polyurethane products, as well as carbamate insecticides. Toluene 2,4-diisocyanate (TDI) is one of the most important commercially used isocyanates. Humans may be exposed to TDI by inhalation, ingestion, dermal and eye contact.
S, Shadnia, M, Ahmadimanesh, M, Ghazi-Khansari, N, Zamani   +3 more
openaire   +1 more source

Synthesis and investigation of poly(urethane-urea) capsules from poly(vinyl alcohol), 2,4-toluene diisocyanate and various diamines.

, 2016
Synthesis and Investigation of Poly(urethane-urea) Capsules from Poly(vinyl alcohol), 2,4-Toluene Diisocyanate and Various ...
Niedritis, Jana,
core