Results 181 to 190 of about 51,076 (258)

Novel Carbazole–Acylthiourea Derivatives: Synthesis, Antimicrobial, Antioxidant, Hemocompatibility, Cytotoxicity, and ADME‐Tox Profiling

ChemistryOpen, Volume 15, Issue 11, November 2026.
We synthesized four novel carprofen‐derived carbazole–acylthiourea propanamides with selective antimicrobial activity against Staphylococcus aureus, Enterococcus faecalis, and Candida albicans. Compound 1a provides combined antioxidant and antihemolytic protection.
Carmen Limban, Ioana Cristina Marinaş, Mariana Carmen Chifiriuc, Miron Teodor Căproiu, Florea Dumitraşcu, Erzsébet‐Eleonóra Kapronczai, Irina Zarafu, Diana Camelia Nuţă, Petre Ioniţă, Speranţa Avram, Cătălina Mareş, Andra Maria Păun, Bogdan Mihai Cristea, Carmellina Daniela Bădiceanu, Ilinca Margareta Vlad, Maria Coandă, Delia Laura Popescu, Coralia Bleotu   +17 more
wiley   +1 more source

Comparative Immunohistochemical Study of Canine Mammary Tumours: Introducing of Triple‐Negative Profile (ER−/PR−/HER2−) in Benign Mammary Tumours of Animal Model

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
The study examined 130 dogs that had mastectomies in Tehran, Iran. Malignant tumours were most commonly carcinomas, while the most frequent benign tumours were fibroadenomas. Blood tests indicated that dogs with malignant tumours had lower red blood cell and haemoglobin levels, signifying anaemia and higher monocyte counts compared to those with benign
Hossein Lak, Amir Amniattalab
wiley   +1 more source

Extreme Polyploidy Reveals Functional Trade‐Offs in Plant Drought Responses

Plant, Cell &Environment, Volume 49, Issue 11, Page 8697-8711, November 2026.
ABSTRACT Polyploidy shapes plant physiology and anatomy, yet the extent to which different ploidy levels influence drought responses remains unclear. Here, we investigated how ploidy affects cell‐level coordination and functional traits associated with water transport and retention.
Javier López‐Jurado, Enrique Mateos‐Naranjo, Francisco Balao, Ajaree Thonglim, Frederic Lens, Timothy J. Brodribb   +5 more
wiley   +1 more source

Visible‐Light‐Initiated, Nickel‐Catalyzed Aminocarbonylation of Alkynyl Iodides to 2‐Ynamides

Advanced Synthesis &Catalysis, Volume 368, Issue 19, 1 October 2026.
Visible light initiates a nickel‐catalyzed aminocarbonylation of alkynyl iodides, enabling the synthesis of 2‐ynamides under low carbon monoxide pressure. The method operates under mild conditions, tolerates a broad substrate scope, and proceeds through a light‐triggered nickel(I)/nickel(III) carbonylative pathway.
Michael Weiser, Alexander Frischauf, Berthold Stöger, Ertan Turhan, Dennis Kurzbach, Katharina Bica‐Schröder   +5 more
wiley   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, Volume 13, Issue 55, 5 October 2026.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Glycyrrhizic Acid Relieves Fatigue Induced by Acute and Chronic Exercise in Mice via Inhibition of the NF‐κB/NLRP3 Signaling Pathway

Brain and Behavior, Volume 16, Issue 10, October 2026.
Molecular mechanism diagram of Gly‐A in the treatment of acute and chronic exercise‐fatigue. ABSTRACT Background Glycyrrhizic acid (Gly‐A) exhibits anti‐inflammatory and antioxidant effects in various central nervous system disorders. Acute fatigue and chronic fatigue (CF) are associated with serious physical and psychological effects.
Xin‐ying Cai, Wen‐jun Li, Cai‐xia Chen, Lu Peng, Li‐chao Yang, Xiao‐ning Lin, Hong‐tao Liu, Jian‐bo Jia, Yan‐chao Jiao, Ying Li   +9 more
wiley   +1 more source

Shear Stress‐Stimulated Trafficking of Endothelial Piezo1 to Splenic Capsule Boosts Spleen Contraction and Exercise Endurance

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
The vasculo‐splenic axis during exercise: shear stress triggers the release of medium/large extracellular vesicles from vascular endothelial cells via activation of Piezo1, shuttling Piezo1 to the smooth muscle cells in the splenic capsule; the translocated Piezo1 within the splenic capsule acts as a downstream effector of the α1‐adrenergic receptor ...
Jing Lou, Mingzong Yang, Yang Hu, Xuyun Liu, Han Li, Zihang Feng, Yuxin Xi, Changyang Xing, Lijun Yuan, Jia Li, Shengpeng Wang, Feng Gao, Xing Zhang   +12 more
wiley   +1 more source

Evaluating the Efficacy of Chitosan‐l‐DOPA MAP Gel for Acute Laryngeal Injury

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 5, October 2026.
ABSTRACT Objectives This study aimed to evaluate the efficacy of an innovative chitosan‐l‐DOPA‐modified microporous annealed particle (MAP) hydrogel in reducing fibrosis and enhancing healing in the treatment of Acute Laryngeal Injury (ALgI). Methods Four experimental treatment groups: uninjured control, sham treated control (saline), nonbioactive MAP ...
Areli Rodriguez‐Ayala, Ryan Stepp, Naushin Ali, Vincent Gray, Rachel Letteri, Patrick S. Cottler, Donald R. Griffin, James J. Daniero   +7 more
wiley   +1 more source

Immune dysregulation in the prostates of C57BL/6Aire−/− mice mirrors that seen in human benign prostatic hyperplasia

The Journal of Pathology, Volume 270, Issue 2, Page 211-225, October 2026.
Abstract Benign prostatic hyperplasia (BPH) is the most common urologic disease in aging men, resulting in significant morbidity. The etiologies of BPH are unknown, though chronic prostatic inflammation is known to promote hyperplasia, fibrotic remodeling, and therapeutic resistance in BPH.
Nadia A Lanman, Meaghan M Broman, Harish Kothandaraman, Gregory M Cresswell, Gada D Awdalkreem, Dilinaer Wusiman, Andree K Kolliegbo, Alexander P Glaser, Brian T Helfand, Renee E Vickman, Jiang Yang, Simon W Hayward, Timothy L Ratliff   +12 more
wiley   +1 more source

Evaluate the Effectiveness of Toluidine Blue for Obtaining Safe Margins in Resection of Oral Squamous Cell Carcinoma. [PDF]

J Maxillofac Oral Surg
Hallur N, Siddiqa A, Zakaullah S, Kothari C, Fatima S, Tejaswini K.   +5 more
europepmc   +1 more source