Results 71 to 80 of about 9,892 (240)
The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors
British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,Stephen P. H. Alexander, Anthony P. Davenport, Eamonn Kelly, Alasdair J. Gibb, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Maria Pia Abbracchio, George R. Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kirstie A. Bennett, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria A. Blaho, Pascal Bonaventure, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Andrew J. Brown, Geoffrey Burnstock, Marta Busnelli, Girolamo Caló, Vanni Caruso, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Arthur Christopoulos, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Frank M. Dautzenberg, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Margarita L. Dubocovich, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Huamei Fu Forsman, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Florence Gbahou, Craig Gerard, Marvin Gershengorn, Michelle Glass, David E. Gloriam, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Christian Gruber, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Deborah S. Hartman, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Laura Heitman, Deron R. Herr, Morley D. Hollenberg, Nicholas D. Holliday, Birgitte Holst, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Paul A. Insel, Kenneth A. Jacobson, Laura H. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Julia Kinsolving, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Luxmichan Laishram, Tobias Langenhan, Christopher J. Langmead, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Rob Leurs, Xaria X. Li, Ines Liebscher, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet J. Maguire, Davide Malfacini, Maurice Manning, Davide Marangon, Kirill Martemyanov, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Richard R. Neubig, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Nicole Perry‐Hauser, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Helena Chengxue Qin, Mark Quinn, Stefano Raffaele, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Alejandro Romeral Buzón, Philippe Rondard, Mette M. Rosenkilde, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Nicole Scholz, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Arun K. Shukla, Khuraijam Dhanachandra Singh, Craig M. Smith, Nicola J. Smith, Claudia Stäubert, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David M. Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Joseph G. Verbalis, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Huixian Wu, Cheng Yang, Chengcan Yao, Richard D. Ye, Nathan Zaidman +206 morewiley +1 more sourceUrinary markers in heart failure – types, timing and thresholds. European Journal of Heart Failure expert consensus document
European Journal of Heart Failure, Volume 27, Issue 11, Page 2372-2396, November 2025.Pathophysiologic mechanisms of heart failure (HF) (i.e. renin–angiotensin–aldosterone system [RAAS], congestion, and inflammation), together with patient‐related factors such as diabetes, hypertension, and chronic kidney disease (CKD), contribute to kidney function decline and glomerular or tubular injury.Masatake Kobayashi, Biykem Bozkurt, Peder Langeland Myhre, Juan Carlos Lopez Azor, Mateusz Guzik, Gracjan Iwanek, Guillaume Baudry, Marta Cobo‐Marcos, Òscar Miró, Jeroen Dauw, Piotr Ponikowski, Wilfried Mullens, Alberto Palazzuoli, Marco Metra, Jan Biegus +14 morewiley +1 more sourceRenal ultrasonography predicts worsening renal function in patients with heart failure under tolvaptan administration
ESC Heart FailureAims Renal dysfunction in patients with chronic heart failure predicts a poor prognosis. Tolvaptan has a diuretic effect in patients with chronic kidney disease and heart failure without adverse effects on renal function.Nobukiyo Tanaka, Yoshio Furukawa, Takuya Maeda, Hiroki Ishihara, Kazuhiro Dan, Masanori Teramura, Kei Ichihashi, Tetsuro Takase, Yuya Takahashi, Daichi Tsuzura, Akira Shinoda, Masato Fujii, Hisashi Okada, Fumiharu Itabashi, Tomohiko Teramoto +14 moredoaj +1 more sourceImpact of non‐cardiovascular factors on cardiovascular death in acute decompensated heart failure: Enhancing predictive models with frailty and comorbid constipation—the Constipation and Frailty Augmented AHEAD score
Geriatrics &Gerontology International, Volume 25, Issue 10, Page 1341-1349, October 2025.We developed the CFA‐AHEAD score by incorporating constipation and frailty into the conventional AHEAD model. This new score significantly improves the prediction of mortality in patients with acute decompensated heart failure. Simple and practical, the CFA‐AHEAD score enhances clinical risk stratification and might support personalized patient ...Tomoaki Ishida, Kei Kawada, Kohei Jobu, Tomoyuki Hamada, Toru Kubo, Hitoshi Fukuda, Yuki Hyohdoh, Kazuya Kawai, Yoko Nakaoka, Toshikazu Yabe, Takashi Furuno, Eisuke Yamada, Hiroaki Kitaoka, Yukihiro Hamada +13 morewiley +1 more sourceThe Association of Hyponatremia with Race, Ethnicity, and Gender in Patients Admitted for Acute Decompensated Heart Failure Diagnoses [PDF]
, 2018 Background: Hyponatremia, defined by a serum sodium concentration less than 135 mEq/L, is seen in approximately 25% of patients admitted with congestive heart failure (CHF).Alvarez, MD, Rene, Carabelli, MD, Evan, Sunder, MD, Vikas +2 morecore +1 more sourcePHS48 Cost-Effectiveness Analysis of Tolvaptan for Hyponatreamia in South Korea [PDF]
, 2005 Lanz, AlfredoPla general de la part frontal de dona ajaguda sobre un suport en forma de llit o
taula. Va ser donada per l'autor, Alfredo Lanz, i simbolitza
el mar Mediterrani.Kang, H.J., Choi, J., Lee, M.Y., Lee, E.K. +3 morecore +1 more sourceMechanisms governing GPCR anterograde transport
FEBS Letters, Volume 599, Issue 17, Page 2420-2438, September 2025.G protein‐coupled receptors (GPCRs) determine human physiology by transducing ligand binding into intracellular signaling. The transport of nascent GPCRs from the endoplasmic reticulum to the cell surface is critical for cellular responsiveness. We discuss mechanisms regulating GPCR trafficking through secretory organelles, retention of disease‐related Kevin Assoumou, Sofia Papadogkonaki, Itziar Muneta‐Arrate, Miriam Stoeber +3 morewiley +1 more source
