Results 61 to 70 of about 5,445 (182)

Pituitary Neurolobectomy induces sustained hypotension in male Wistar rats and normalizes blood pressure in male spontaneously hypertensive rats

Physiological Reports, Volume 14, Issue 11, June 2026.
Abstract Arginine vasopressin is primarily recognized as an osmoregulatory hormone; however, its contribution to vascular tone and blood pressure regulation under basal and hypertensive conditions remains debated. This study examined the effects of vasopressin deficiency induced by neurointermediate pituitary lobectomy in Wistar and spontaneously ...
Gloria Marcela Villanueva‐Rodríguez, Norma A. Bobadilla, J. Luis Quintanar, Claudia Verónica Rivera‐Cerecedo, David Roberto Chavira‐Ramírez, Kalman Kovacs, Andrés Quintanar‐Stephano   +6 more
wiley   +1 more source

Tolvaptan [PDF]

British Journal of Clinical Pharmacology, 2011
Eline A, Dubois, Robert, Rissmann, Adam F, Cohen   +2 more
openaire   +3 more sources

Tolerability of Aquaretic-Related Symptoms Following Tolvaptan for Autosomal Dominant Polycystic Kidney Disease: Results From TEMPO 3:4

Kidney International Reports, 2017
In the randomized placebo-controlled Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and its Outcomes (TEMPO) 3:4 trial, tolvaptan slowed kidney growth and renal function decline in subjects with autosomal ...
Olivier Devuyst, Arlene B. Chapman, Susan E. Shoaf, Frank S. Czerwiec, Jaime D. Blais   +4 more
doaj   +1 more source

Best Evidence Summary for Volume Management of Patients With Heart and Kidney Comorbidity

Nursing Open, Volume 13, Issue 5, May 2026.
ABSTRACT Objective To summarise the best evidence of volume management of patients with coexisting cardiac and renal disorders. Design An evidence summary, a form of rapid review. Methods A systematic search was conducted in guideline websites, professional association websites and six databases included Web of Science, Embase, CIHAHL, PubMed, CNKI ...
Huang Aoli, Chen Xia, Zhu Xujing, Yang Qiaozhen, Yang Yeyao, Feng Jiehui   +5 more
wiley   +1 more source

Life‐Threatening Prolonged ICANS Following Tarlatamab Treatment in Extensive‐Stage Small Cell Lung Cancer With Brain Metastases: A Case Report

Respirology Case Reports, Volume 14, Issue 5, May 2026.
A patient with extensive‐stage small cell lung cancer developed life‐threatening, prolonged ICANS shortly after tarlatamab treatment. Brain MRI revealed previously unrecognized multiple brain metastases, suggesting a possible link between occult intracranial disease and severe neurotoxicity.
Hiroyuki Arai, Shinji Sasada, Hiroki Kazahari, Yuya Homma, Kyohei Kaburaki   +4 more
wiley   +1 more source

Tolvaptan Use in SIAD (Syndrome of Inappropriate Antidiuresis)

, 2021
Background: SIAD (Syndrome of Inappropriate Antidiuresis) is the commonest cause of hyponatraemia in hospital inpatients. Hyponatraemia is associated with increased length of stay and worse primary clinical outcomes.
Sushma Burri (19317760), Sathish Babu Parthasarathy (19317763)   +1 more
core  

Long-Term Effects of High-Dose Tolvaptan for Autosomal Dominant Polycystic Kidney Disease Patients

Case Reports in Nephrology and Dialysis, 2020
Tolvaptan, a vasopressin V2 receptor antagonist, was initially approved in Japan for treatment of autosomal dominant polycystic kidney disease (ADPKD).
Shinya Nakatani, Eiji Ishimura, Yuri Machiba, Kenta Fujimoto, Hideki Uedono, Akihiro Tsuda, Katsuhito Mori, Masanori Emoto, Masaaki Inaba   +8 more
doaj   +1 more source

A Case of Worsened Refractory Ascites due to Prednisolone Administration for Stricture Prevention after Endoscopic Submucosal Dissection for Extensive Early Esophageal Cancer: Case Report and Literature Review

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Endoscopic submucosal dissection (ESD) is widely used for early esophageal cancer, even in patients with liver cirrhosis (LC). Corticosteroids, administered orally or by local injection, are often used to prevent post‐ESD esophageal stricture. However, their safety in patients with decompensated LC and refractory ascites remains unclear. A man
Yuki Tamura, Masanori Sekiguchi, Kaho Honda, Yu Maruyama, Kenta Ito, Makiko Inoue, Mitsuhiko Shibasaki, Daichi Takizawa, Hirotaka Arai, Toshio Uraoka   +9 more
wiley   +1 more source

Idiosyncratic hepatic toxicity in autosomal dominant polycystic kidney disease (ADPKD) patient in combined treatment with tolvaptan and amoxicillin/clavulanic acid: a case report

BMC Nephrology, 2019
Background Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disease characterized by the presence of renal cysts. Over time the expanding cysts lead to progressive renal failure.
Angela Maria Pellegrino, Luigi Annicchiarico Petruzzelli, Eleonora Riccio, Antonio Pisani   +3 more
doaj   +1 more source

Short-term efficacy and safety of tolvaptan in patients with left ventricular assist devices

, 2020
Copyright © 2019 by the ASAIO Tolvaptan is an effective therapy for heart failure patients with symptomatic congestion and hyponatremia. The efficacy of its use in patients with continuous-flow left ventricular assist devices (LVADs) is unknown.
Takeo Fujino, Teruhiko Imamura, Kalantari, Sara, Sayer, Gabriel, Sara Kalantari, Nitasha Sarswat, Nguyen, Ann, Nikhil Narang, Jeevanandam, Valluvan, Daisuke Nitta, Chung, Ben, Labuhn, Colleen, Gabriel Sayer, Nitta, Daisuke, Gene Kim, Bryan Smith, Colleen LaBuhn, Uriel, Nir, Raikhelkar, Jayant, Smith, Bryan, Narang, Nikhil, Sarswat, Nitasha, Daniel Rodgers, Rodgers, Daniel, Kim, Gene, Ben Chung, Imamura, Teruhiko, Nir Uriel, Valluvan Jeevanandam, Ann Nguyen, Jayant Raikhelkar, Fujino, Takeo   +31 more
core   +1 more source