Results 91 to 100 of about 1,700,838 (253)
AIP Advances, 2015 Family of “breathing crystals” is the polymer-chain complexes of Cu(hfac)2 with nitroxides. The polymer chains consist of one-, two- or three-spin clusters.
Vitaly A. Morozov +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Surface imaging of metallic material fractures using optical coherence tomography [PDF]
, 2014 We demonstrate the capability of optical coherence tomography (OCT) to perform topography of metallic surfaces after being subjected to ductile or brittle fracturing.
Demian, D. +4 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Optical Coherence Tomography for Examination of Parchment Degradation [PDF]
, 2006 A novel application of Optical Coherence Tomography utilizing infrared light of 830 nm central wavelength for non invasive examination of the structure of parchment, some covered with iron gall ink, is presented.
Pircher, M +7 more
core
Digital DiagnosticsBACKGROUND: The validation of quantitative cerebral blood flow assessment using non-contrast magnetic resonance imaging remains unresolved. The optimal approach involves applying a method based on a different physiological model to enhance the ...
Vladimir V. Popov +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Efficient non-linear 3D electrical tomography reconstruction
, 2001 Non-linear electrical tomography imaging can be performed efficiently if certain optimisations are applied to the computational reconstruction process. We present a 3D non-linear reconstruction algorithm based on a regularized conjugate gradient solver ...
Daniell, G.J. +3 more
core +1 more source