Results 161 to 170 of about 2,551,121 (363)

A Data-Adaptive Compressed Sensing Approach to Polarimetric SAR Tomography of Forested Areas

open access: yes, 2013
Super-resolution imaging via compressed sensing (CS)-based spectral estimators has been recently introduced to synthetic aperture radar (SAR) tomography.
Nannini, Matteo   +2 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Optical Coherence Tomography for Examination of Parchment Degradation

open access: yes, 2006
A novel application of Optical Coherence Tomography utilizing infrared light of 830 nm central wavelength for non invasive examination of the structure of parchment, some covered with iron gall ink, is presented.
Pircher, M   +7 more
core  

Guidelines for assessment of bone microstructure in rodents using micro–computed tomography

open access: yesJournal of Bone and Mineral Research, 2010
M. Bouxsein   +5 more
semanticscholar   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Efficient non-linear 3D electrical tomography reconstruction

open access: yes, 2001
Non-linear electrical tomography imaging can be performed efficiently if certain optimisations are applied to the computational reconstruction process. We present a 3D non-linear reconstruction algorithm based on a regularized conjugate gradient solver ...
Blott, B H   +7 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Fibre optic fizeau intererometer for optical coherence tomography [PDF]

open access: yes, 2006
The aim of the project was to develop the Fizeau interferometer configuration to take advantage of the benefits derived from its “downlead insensitivity” to temperature and polarisation fading.
Casaubieilh, P.
core  

Optical Coherence Tomography

open access: yesLEOS '92 Conference Proceedings, 1991
David Huang   +10 more
semanticscholar   +1 more source

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