Results 161 to 170 of about 2,551,121 (363)
A Data-Adaptive Compressed Sensing Approach to Polarimetric SAR Tomography of Forested Areas
Super-resolution imaging via compressed sensing (CS)-based spectral estimators has been recently introduced to synthetic aperture radar (SAR) tomography.
Nannini, Matteo +2 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Optical Coherence Tomography for Examination of Parchment Degradation
A novel application of Optical Coherence Tomography utilizing infrared light of 830 nm central wavelength for non invasive examination of the structure of parchment, some covered with iron gall ink, is presented.
Pircher, M +7 more
core
Guidelines for assessment of bone microstructure in rodents using micro–computed tomography
M. Bouxsein +5 more
semanticscholar +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Efficient non-linear 3D electrical tomography reconstruction
Non-linear electrical tomography imaging can be performed efficiently if certain optimisations are applied to the computational reconstruction process. We present a 3D non-linear reconstruction algorithm based on a regularized conjugate gradient solver ...
Blott, B H +7 more
core
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Fibre optic fizeau intererometer for optical coherence tomography [PDF]
The aim of the project was to develop the Fizeau interferometer configuration to take advantage of the benefits derived from its “downlead insensitivity” to temperature and polarisation fading.
Casaubieilh, P.
core

